Clinical Trials Updated in 2025

NCT06510192 | NOT_YET_RECRUITING | NA

60 participants

Yuva Sath: A Peer-led Behavioral Intervention to Support Substance Use Treatment and HIV Prevention Among Young People Who Inject Drugs in India

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2027-01-31
Completion:: 2028-07-31

Conditions

Hiv
Substance Use Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT06480786 | RECRUITING | NA

15 participants

SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2024-12-18
Completion:: 2027-01-31

Conditions

Peripheral Arterial Disease
Painful Diabetic Neuropathy
Diabetes Mellitus, Type 2
Chronic Pain
Spinal Cord Stimulation
Chronic Pain Syndrome
Limb Pain

Interventions

DEVICE

No Results Yet

NCT06471348 | RECRUITING | NA

128 participants

Postoperative Pain Control in AIS Using Liposomal Bupivacaine vs. 0.25% Bupivacaine With Epinephrine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2025-08-15
Completion:: 2027-08-15

Conditions

Post Operative Pain
Spinal Fusion

Interventions

DRUG

No Results Yet

NCT06449352 | COMPLETED | PHASE4

100 participants

Effect of Netarsudil vs Brimonidine in NTG Patients on Latanoprost

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2024-06-13
Completion:: 2025-09-22

Conditions

Normal Tension Glaucoma

Interventions

DRUG

No Results Yet

NCT06436248 | ACTIVE_NOT_RECRUITING

24 participants

Polygenic Risk Scores and Multi-cancer Early Detection for Ovarian Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-22
Start Date:: 2024-07-01
Completion:: 2026-10-31

Conditions

Ovarian Cancer
BRCA Mutation

No Results Yet

NCT06401174 | ENROLLING_BY_INVITATION | NA

1800 participants

Patient Navigation for Colorectal Cancer Screening

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2024-06-01
Completion:: 2028-01-30

Conditions

Colorectal Cancer Screening

Interventions

BEHAVIORAL

No Results Yet

NCT06384001 | RECRUITING | NA

66 participants

Meditation for Older Adults With Chronic Low Back Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2025-09-24
Completion:: 2026-12-31

Conditions

Chronic Low Back Pain

Interventions

BEHAVIORAL

No Results Yet

NCT06366724 | RECRUITING | PHASE2

160 participants

LIFT: Life Improvement Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2024-09-10
Completion:: 2026-09-30

Conditions

ME/CFS
Long COVID
PASC

Interventions

DRUG
OTHER

No Results Yet

NCT06331156 | COMPLETED | PHASE3

400 participants

A Study on the Immune Response and Safety of Inactivated Poliovirus Vaccine (IPV) When Co-administered With Human Rotavirus (HRV) Porcine Circovirus (PCV)-Free Vaccine in Healthy Chinese Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2024-03-22
Completion:: 2024-10-22

Conditions

Gastroenteritis

Interventions

COMBINATION_PRODUCT

Results Available

NCT06285123 | COMPLETED

69 participants

Implementing the COMFORT Guidelines for Postpartum Pain Management

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-22
Start Date:: 2024-01-26
Completion:: 2025-07-01

Conditions

Postpartum Pain
Opioid Stewardship
Maternity Care
Obstetric Care

Interventions

BEHAVIORAL

No Results Yet

NCT06244199 | RECRUITING | NA

250 participants

Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2024-11-01
Completion:: 2027-03-31

Conditions

Cardiovascular Diseases
Cardiac Rehabilitation
Transition of Care

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06179108 | COMPLETED | PHASE2

359 participants

Randomized, Double-blinded, Placebo-controlled, Evaluating the Treatment With LB-102 in Patients With Acute Schizophrenia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2023-11-29
Completion:: 2024-12-04

Conditions

Schizophrenia

Interventions

DRUG

Results Available

NCT06169800 | RECRUITING | NA

20 participants

Biologic Augment of the Medial Patellofemoral Ligament Following Primary Lateral Patellofemoral Dislocation (BioPPD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2024-01-15
Completion:: 2026-12-31

Conditions

Patellofemoral Dislocation

Interventions

DEVICE

No Results Yet

NCT06104735 | RECRUITING | NA

12 participants

Finding the Best Combination of Brain and Spinal Cord Stimulation With Hand Training After Spinal Cord Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2024-05-24
Completion:: 2026-11-30

Conditions

Spinal Cord Injuries

Interventions

PROCEDURE

No Results Yet

NCT06100276 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

20 participants

Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants With SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2024-08-01
Completion:: 2026-09-30

Conditions

Amyotrophic Lateral Sclerosis

Interventions

DRUG

No Results Yet

NCT06060587 | WITHDRAWN | PHASE2

0 participants

Randomized Phase II Study of ADT + Abiraterone vs ADT + Docetaxel + Abiraterone

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2023-10-19
Completion:: 2024-05-03

Conditions

Prostate Cancer

Interventions

DRUG

No Results Yet

NCT06052566 | COMPLETED | PHASE1

22 participants

A Study of Efinopegdutide in Participants With Hepatic Impairment (MK-6024-014)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2023-11-21
Completion:: 2024-12-05

Conditions

Non-alcoholic Steatohepatitis
Hepatic Impairment

Interventions

DRUG

Results Available

NCT06046482 | TERMINATED | PHASE2

4 participants

Phase II Trial of Magrolimab and Cetuximab With Pembrolizumab or Docetaxel for Recurrent/Metastatic Head Neck Squamous Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2023-11-28
Completion:: 2024-08-26

Conditions

Head Neck
Squamous Cell Carcinoma of Head and Neck

Interventions

DRUG

Results Available

NCT05877885 | RECRUITING | NA

84 participants

Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2025-09-19
Completion:: 2028-11-01

Conditions

Major Depressive Disorder
Apathy

Interventions

BEHAVIORAL

No Results Yet

NCT05856123 | COMPLETED | NA

100 participants

A Study to Evaluate SimPull for Lateral Patient Transfer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2023-11-16
Completion:: 2024-08-14

Conditions

Lateral Patient Transfer

Interventions

DEVICE
OTHER

Results Available

NCT05769283 | COMPLETED | NA

52 participants

Vaginal Injection of Platelet Rich Plasma for Sexual Function

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2023-08-18
Completion:: 2025-03-21

Conditions

Sexual Behavior
Sexual Activity

Interventions

OTHER

No Results Yet

NCT05727878 | TERMINATED | PHASE2

103 participants

Trial to Evaluate Safety and Efficacy of KPI-012 Ophthalmic Solution in Participants With PCED

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2023-02-07
Completion:: 2025-09-29

Conditions

Persistent Corneal Epithelial Defect

Interventions

DRUG

No Results Yet

NCT05720624 | WITHDRAWN | PHASE1

0 participants

Pharmacodynamic Analyses of Metabolic Agents Following Brain Radiation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2025-10-20
Completion:: 2025-10-20

Conditions

Malignant Central Nervous System Neoplasm

Interventions

DRUG
OTHER
PROCEDURE

No Results Yet

NCT05711108 | COMPLETED

86 participants

Continuous Glucose Monitoring (CGM) in Long Term Care (LTC) Facilities

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-22
Start Date:: 2022-01-19
Completion:: 2024-11-30

Conditions

Diabetes
Hypoglycemia
Aging

No Results Yet

NCT05694013 | TERMINATED | PHASE2/PHASE3

49 participants

Clinical Impact and Utility of Digital Health Solutions in Participants Receiving Systemic Treatment in Clinical Practice

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2023-02-27
Completion:: 2024-06-30

Conditions

Cancer

Interventions

DEVICE
DRUG
OTHER

Results Available

NCT05552326 | COMPLETED | PHASE3

446 participants

A Study of Olezarsen Administered Subcutaneously to Participants With Severe Hypertriglyceridemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2022-08-31
Completion:: 2024-12-17

Conditions

Severe Hypertriglyceridemia

Interventions

DRUG

No Results Yet

NCT05544708 | COMPLETED | NA

71 participants

Using Grassroots Wellness Coaching to Enhance Reach and Sustainability of Behavioral Weight Management

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2023-05-01
Completion:: 2025-05-30

Conditions

Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT05514119 | TERMINATED | PHASE2

6 participants

A Study to Assess the Role of Fenofibrate in Preventing Ischemic Cholangiopathy After Liver Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2022-08-17
Completion:: 2024-06-30

Conditions

Liver Transplant

Interventions

DRUG

Results Available

NCT05512208 | RECRUITING | PHASE2

55 participants

A Phase 2 Study of Avutometinib (VS-6766) Plus Defactinib

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2023-02-06
Completion:: 2027-12-31

Conditions

Endometrioid Cancer
Mucinous Ovarian Cancer
High Grade Serous Ovarian Cancer
Cervical Cancer
Solid Tumor

Interventions

DRUG

No Results Yet

NCT05508906 | RECRUITING | PHASE1

190 participants

Phase 1b Study of OP-1250 (Palazestrant) in Combination With Ribociclib, Alpelisib, Everolimus, or Atirmociclib in ER+, HER2- Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2022-08-31
Completion:: 2027-12-31

Conditions

Metastatic Breast Cancer
ER-positive Breast Cancer
HER2-negative Breast Cancer
Breast Cancer
Locally Advanced Breast Cancer

Interventions

DRUG

No Results Yet

NCT05368064 | ENROLLING_BY_INVITATION

300 participants

Cleidocranial Dysplasia (CCD): From Genotype to Phenotype and Considerations for Care

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-22
Start Date:: 2021-10-01
Completion:: 2027-12-31

Conditions

Cleidocranial Dysostosis

Interventions

OTHER

No Results Yet

NCT05341947 | WITHDRAWN | PHASE1

0 participants

Activated Autologous T Cells Against Glioma Cancer Stem Cell Antigens for Patients With Recurrent Glioblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2026-06-30
Completion:: 2027-12-31

Conditions

Recurrent Glioblastoma

Interventions

BIOLOGICAL

No Results Yet

NCT05328375 | COMPLETED | NA

10 participants

Telehealth-enhanced Hybrid Cardiac Rehabilitation Among Acute Coronary Syndrome Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2022-03-11
Completion:: 2023-04-26

Conditions

Acute Coronary Syndrome
Myocardial Infarction

Interventions

BEHAVIORAL

Results Available

NCT05295953 | COMPLETED | NA

4 participants

Accelerated Transcranial Magnetic Stimulation (TMS) for Smoking Cessation in People Living With HIV/AIDS (PLWHA)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2022-04-01
Completion:: 2024-07-31

Conditions

Hiv
Tobacco Smoking

Interventions

DEVICE

Results Available

NCT05275998 | COMPLETED | PHASE1/PHASE2

51 participants

TMB-365 and TMB-380 in Suppressed HIV-1 Infected Individuals

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2022-07-05
Completion:: 2024-11-20

Conditions

HIV-1-infection

Interventions

DRUG

Results Available

NCT05229601 | TERMINATED | PHASE1

31 participants

A Study of HFB301001 in Adult Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2022-04-20
Completion:: 2024-05-30

Conditions

Soft Tissue Sarcoma
Renal Cell Carcinoma
Uterine Carcinosarcoma
Hepatocellular Carcinoma
Head and Neck Squamous Cell Carcinoma
Melanoma

Interventions

DRUG

No Results Yet

NCT05166356 | COMPLETED

372 participants

Determinants and Effects in the Use of NOHARM Pain Management

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-22
Start Date:: 2022-03-01
Completion:: 2024-02-01

Conditions

Surgical Procedure, Unspecified

No Results Yet

NCT05109234 | COMPLETED | PHASE3

84 participants

A Study to Test the Long-term Safety, Tolerability and Efficacy of Brivaracetam in Study Participants 2 to 26 Years of Age With Childhood Absence Epilepsy or Juvenile Absence Epilepsy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2022-03-30
Completion:: 2025-03-18

Conditions

Childhood Absence Epilepsy
Juvenile Absence Epilepsy

Interventions

DRUG

Results Available

NCT05049460 | COMPLETED | NA

23 participants

Adjunctive Transcranial Stimulation to Reduce Impulsivity in Opiate Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2021-09-15
Completion:: 2024-07-31

Conditions

Opioid-use Disorder
Tobacco Use Disorder

Interventions

DEVICE

Results Available

NCT05030753 | COMPLETED | NA

249 participants

iSIPsmarter: An RCT Evaluating the Efficacy of a Technology-Based Intervention to Reduce Sugary Drinks in Rural Appalachia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-22
Start Date:: 2021-08-02
Completion:: 2023-02-28

Conditions

Diet Habit
Sugar-Sweetened Beverages

Interventions

BEHAVIORAL

Results Available