Clinical Trials

NCT04194944 | ACTIVE_NOT_RECRUITING | PHASE3

261 participants

A Study of Selpercatinib (LY3527723) in Participants With Advanced or Metastatic RET Fusion-Positive Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2020-02-17

Completion:

2023-05-01

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT04152772 | COMPLETED | NA

62 participants

Effect of tDCS Timing on Safety Memory in PTSD

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2019-11-22

Completion:

2024-01-31

Conditions

• PTSD

Interventions

• DEVICE

Results Available

NCT04120493 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

43 participants

Safety and Proof-of-Concept (POC) Study With AMT-130 in Adults With Early Manifest Huntington's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2019-09-06

Completion:

2029-06-30

Conditions

• Huntington's Disease

Interventions

• GENETIC
• OTHER

No Results Yet

NCT04112810 | COMPLETED | PHASE2

51 participants

Tildrakizumab for Prevention of Acute Graft-Versus-Host Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2020-03-01

Completion:

2024-06-01

Conditions

• Hematologic Malignancies

Interventions

• DRUG

Results Available

NCT04099992 | RECRUITING | NA

150 participants

Mindfulness in Chronic Kidney Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2019-09-20

Completion:

2026-09-30

Conditions

• Chronic Kidney Diseases

Interventions

• BEHAVIORAL
• DEVICE

No Results Yet

NCT03937713 | COMPLETED | PHASE4

53 participants

Effectiveness of Combining Behavioral and Pharmacologic Therapy for Complex Insomnia in Veterans With PTSD

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2019-12-01

Completion:

2024-09-30

Conditions

• Complex Insomnia

Interventions

• DRUG
• BEHAVIORAL

Results Available

NCT03906071 | COMPLETED | PHASE3

577 participants

Phase 3 Study of Sitravatinib Plus Nivolumab vs Docetaxel in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2019-07-15

Completion:

2023-03-20

Conditions

• Metastatic Non-Squamous Non-Small Cell Lung Cancer

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT03835702 | COMPLETED | NA

56 participants

SAMPAP Trial -Impact of a Novel Sleep Apnea Management Group Intervention on Positive Airway Pressure Adherence

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2019-04-01

Completion:

2022-11-18

Conditions

• Sleep Apnea

Interventions

• OTHER

No Results Yet

NCT03790332 | COMPLETED | PHASE1/PHASE2

59 participants

Phase 1/2 Dose Finding and Safety Study of Ibrutinib in Pediatric Subjects With Chronic Graft Versus Host Disease (cGVHD)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2018-11-19

Completion:

2025-10-09

Conditions

• Chronic Graft Versus Host Disease

Interventions

• DRUG

No Results Yet

NCT03767257 | COMPLETED | PHASE2

25 participants

A Study of Colesevelam for Lenalidomide-Associated Diarrhea

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2018-12-03

Completion:

2024-11-27

Conditions

• Multiple Myeloma
• Diarrhea

Interventions

• DRUG

Results Available

NCT03753204 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

20 participants

Salt-Sensitivity and Immunity Cell Activation

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2021-09-01

Completion:

2026-09-01

Conditions

• High Blood Pressure
• Salt; Excess
• Inflammation

Interventions

• DRUG

No Results Yet

NCT03609177 | COMPLETED | NA

13800 participants

Advance Care Planning: Promoting Effective and Aligned Communication in the Elderly

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2020-04-15

Completion:

2022-11-23

Conditions

• Other Cancer

Interventions

• OTHER

Results Available

NCT03602235 | COMPLETED | PHASE1

6 participants

High Dose Ascorbic Acid for Plasma Cell Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2019-03-05

Completion:

2024-07-01

Conditions

• Multiple Myeloma

Interventions

• OTHER
• DRUG

No Results Yet

NCT03590652 | TERMINATED | PHASE2

23 participants

Daratumumab, Ixazomib, Pomalidomide, and Dexamethasone as Salvage Therapy in Relapsed/Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2018-10-17

Completion:

2025-07-02

Conditions

• Relapsed/Refractory Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT03529110 | ACTIVE_NOT_RECRUITING | PHASE3

524 participants

DS-8201a Versus T-DM1 for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive, Unresectable and/or Metastatic Breast Cancer Previously Treated With Trastuzumab and Taxane [DESTINY-Breast03]

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2018-08-09

Completion:

2021-05-21

Conditions

• Breast Cancer

Interventions

• DRUG

Results Available

NCT03514407 | TERMINATED | PHASE1

25 participants

A Study of INCB059872 in Relapsed or Refractory Ewing Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2018-06-27

Completion:

2020-06-25

Conditions

• Relapsed Ewing Sarcoma

Interventions

• DRUG

No Results Yet

NCT03513549 | SUSPENDED

10000 participants

Observational Study Evaluating the Safety of ADASUVE® in Agitation Associated With Schizophrenia or Bipolar I Disorder

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-21

Start Date:

2014-11-04

Completion:

2027-02-28

Conditions

• Agitation,Psychomotor

Interventions

• DRUG

No Results Yet

NCT03513484 | ACTIVE_NOT_RECRUITING | PHASE1

44 participants

Nintedanib and Azacitidine in Treating Participants With HOX Gene Overexpression Relapsed or Refractory Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2018-11-14

Completion:

2023-12-11

Conditions

• Acute Myeloid Leukemia With t(9;11)(p22.3;q23.3); MLLT3-KMT2A
• Fibroblast Growth Factor Basic Form Measurement
• FLT3 Internal Tandem Duplication
• Recurrent Adult Acute Myeloid Leukemia
• Refractory Acute Myeloid Leukemia

Interventions

• DRUG
• OTHER

No Results Yet

NCT03320642 | TERMINATED | PHASE1

84 participants

GRAVITAS-119: Itacitinib in Combination With Calcineurin Inhibitor-Based Interventions for the Prophylaxis of Graft-Versus Host Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2018-02-27

Completion:

2021-02-25

Conditions

• Hematologic Malignancies

Interventions

• DRUG

No Results Yet

NCT03269994 | COMPLETED | PHASE3

967 participants

Does Cefoxitin or Piperacillin-Tazobactam Prevent Postoperative Surgical Site Infections After Pancreatoduodenectomy?

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2017-11-21

Completion:

2025-01-28

Conditions

• Pancreatic Cancer
• Pancreas Cancer
• Pancreatic Diseases

Interventions

• DRUG

Results Available

NCT03144661 | TERMINATED | PHASE1

25 participants

An Open-Label Safety and Tolerability Study of INCB062079 in Subjects With Advanced Hepatocellular Carcinoma and Other Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2017-05-25

Completion:

2020-06-10

Conditions

• Hepatocellular Carcinoma (HCC)
• Cholangiocarcinoma
• Esophageal Cancer
• Nasopharyngeal Cancer
• Ovarian Cancer
• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT03104257 | COMPLETED

162 participants

The Neural Correlates of Cannabis Use

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-21

Start Date:

2016-12-31

Completion:

2022-04-27

Conditions

• Cannabis Dependence
• Healthy

Interventions

• DRUG

No Results Yet

NCT03081156 | COMPLETED | PHASE4

52 participants

The Effect of BEVESPI AEROSPHERE ® Therapy on Exercise Tolerance in COPD

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2017-03-27

Completion:

2019-01-01

Conditions

• Pulmonary Disease, Chronic Obstructive

Interventions

• DRUG

Results Available

NCT03066596 | COMPLETED | NA

530 participants

Promoting Asthma Guidelines and Management Through Technology-Based Intervention and Care Coordination

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2017-03-07

Completion:

2024-08-24

Conditions

• Asthma Childhood

Interventions

• BEHAVIORAL

Results Available

NCT03015805 | COMPLETED | NA

310 participants

Teen Success Project

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2017-10-01

Completion:

2022-09-14

Conditions

• Substance Abuse

Interventions

• BEHAVIORAL

No Results Yet

NCT02959437 | TERMINATED | PHASE1/PHASE2

70 participants

Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2017-02-27

Completion:

2019-02-15

Conditions

• Solid Tumors
• Advanced Malignancies
• Metastatic Cancer

Interventions

• DRUG

Results Available

NCT02711137 | TERMINATED | PHASE1/PHASE2

137 participants

Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2016-05-18

Completion:

2019-02-13

Conditions

• Solid Tumors

Interventions

• DRUG

Results Available

NCT02605421 | RECRUITING | PHASE2

12 participants

Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2016-06-30

Completion:

2026-10-01

Conditions

• Neuroblastoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT02602769 | RECRUITING

12 participants

Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-21

Start Date:

2015-11-30

Completion:

2026-12-31

Conditions

• Childhood Obesity
• Morbid Obesity

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT02286817 | COMPLETED | PHASE1

30 participants

Phase I Single Dose, Open-Label Pharmacokinetic Study and Single-Blind, Placebo-Controlled Dose Escalation Study of NFC-1 in Adolescents With Attention-Deficit Hyperactivity Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2015-01-31

Completion:

2015-05-31

Conditions

• Attention-deficit Hyperactivity Disorder (ADHD)

Interventions

• DRUG

No Results Yet

NCT02107703 | ACTIVE_NOT_RECRUITING | PHASE3

669 participants

A Study of Abemaciclib (LY2835219) Combined With Fulvestrant in Women With Hormone Receptor Positive HER2 Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2014-07-22

Completion:

2017-02-14

Conditions

• Breast Neoplasms

Interventions

• DRUG

Results Available

NCT01998750 | RECRUITING

500 participants

Study to Investigate Genetic Causes of Severe Early Childhood Onset Obesity.

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-21

Start Date:

2014-02-28

Completion:

2026-12-31

Conditions

• Obesity

No Results Yet

NCT01720836 | RECRUITING | PHASE1/PHASE2

30 participants

Study of the Immune Response of MUC1 (Mucin1) Peptide Vaccine for Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2012-11-30

Completion:

2027-10-31

Conditions

• Non-small Cell Lung Cancer (NSCLC)

Interventions

• BIOLOGICAL

No Results Yet

NCT01508312 | COMPLETED | PHASE2

66 participants

Brentuximab Vedotin (SGN-35) in Transplant Eligible Patients With Relapsed or Refractory Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2012-01-05

Completion:

2024-03-14

Conditions

• Hodgkin's Lymphoma

Interventions

• DRUG

Results Available

NCT00881920 | ACTIVE_NOT_RECRUITING | PHASE1

54 participants

Kappa-CD28 T Lymphocytes, Chronic Lymphocytic Leukemia, B-cell Lymphoma or Multiple Myeloma, CHARKALL

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-21

Start Date:

2009-07-31

Completion:

2018-07-31

Conditions

• Lymphoma
• Myeloma
• Leukemia

Interventions

• BIOLOGICAL

No Results Yet

NCT07218796 | RECRUITING | PHASE3

400 participants

Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-20

Start Date:

2025-10-28

Completion:

2029-05-31

Conditions

• Cataract
• Glaucoma
• Ocular Hypertension

Interventions

• DRUG
• DEVICE

No Results Yet

NCT07218783 | RECRUITING | PHASE3

400 participants

Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-20

Start Date:

2025-10-15

Completion:

2029-03-31

Conditions

• Cataract
• Glaucoma
• Ocular Hypertension

Interventions

• DRUG
• DEVICE

No Results Yet

NCT07218692 | NOT_YET_RECRUITING | PHASE2

35 participants

RP2 and Tivozanib for the Treatment of Metastatic Renal Cell Cancer After Progression on Immunotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-20

Start Date:

2026-08-11

Completion:

2027-08-11

Conditions

• Advanced Clear Cell Renal Cell Carcinoma
• Advanced Renal Cell Carcinoma
• Advanced Sarcomatoid Renal Cell Carcinoma
• Metastatic Clear Cell Renal Cell Carcinoma
• Metastatic Renal Cell Carcinoma
• Metastatic Sarcomatoid Renal Cell Carcinoma
• Recurrent Renal Cell Carcinoma
• Stage III Renal Cell Cancer AJCC v8
• Stage IV Renal Cell Cancer AJCC v8

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG

No Results Yet

NCT07218679 | ACTIVE_NOT_RECRUITING | NA

140 participants

Clinical Trial on the Use of Stratafix Symmetric vs. Resorbable Monofilament for Closure of Large Median Laparotomy in Oncological Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-20

Start Date:

2025-05-21

Completion:

2028-02-28

Conditions

• Incisional Hernia After Midline Laparotomy

Interventions

• DEVICE

No Results Yet

NCT07218640 | RECRUITING | NA

60 participants

Aimmune Longitudinal Collaboration Study

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-20

Start Date:

2025-10-31

Completion:

2026-07-31

Conditions

• Stool Spore Colony Forming Units
• Microbiome Composition
• Dietary Fiber
• Stress

Interventions

• OTHER

No Results Yet