Clinical Trials Updated in 2025

NCT07214857 | COMPLETED

1385 participants

Potential Eligibility and Estimated Preventable Cardiovascular Disease Events From Inclisiran Treatment in the United States

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2024-03-29
Completion:: 2024-10-09

Conditions

Cardiovascular Disease

No Results Yet

NCT07214714 | NOT_YET_RECRUITING | PHASE4

70 participants

Hemodynamic and Cardiac Effects of Dexmedetomidine Versus Fentanyl by Intravenous Infusion as Adjuncts to General Anesthesia in Patients Undergoing Major Abdominal Cancer Surgeries.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-11-01
Completion:: 2026-11-01

Conditions

Abdominal Cancer Surgeries

Interventions

DRUG

No Results Yet

NCT07214701 | NOT_YET_RECRUITING | PHASE4

58 participants

Sedative and Analgesic Effects of Dexmedetomidine Versus Ketamine in Patients Undergoing Varicocelectomy Under Spinal Anaesthesia: A Prospective Randomized Comparative Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-11-01
Completion:: 2026-11-01

Conditions

Varicocelectomy

Interventions

DRUG

No Results Yet

NCT07214649 | NOT_YET_RECRUITING | PHASE2

25 participants

Organoids for Bile Leaks

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2026-01-31
Completion:: 2030-06-30

Conditions

Biliary Anastomosis Complication

Interventions

BIOLOGICAL

No Results Yet

NCT07214623 | NOT_YET_RECRUITING

200 participants

Prospective Multi-center Single Arm Study for Subjects With Chronic Subdural Hematoma Treated With i-ED COILs, Either Alone or in Combination With Burr-holes or Mini-craniotomy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-11-30
Completion:: 2026-11-30

Conditions

Chronic Subdural Hematoma
cSDH
Chronic Subdural Hematomas

Interventions

DEVICE

No Results Yet

NCT07214545 | RECRUITING | NA

60 participants

External Trigeminal Nerve Stimulation for Children With ASD + ADHD to Reduce Elevated Symptoms

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-10-06
Completion:: 2027-09-30

Conditions

Attention Deficit Disorder With Hyperactivity (ADHD)
Autism Spectrum Disorder (ASD)

Interventions

DEVICE

No Results Yet

NCT07214480 | RECRUITING | NA

24 participants

Treatment for /s/ Production Errors in Children With Speech Sound Errors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-06-09
Completion:: 2026-11-30

Conditions

Speech Sound Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07214441 | ENROLLING_BY_INVITATION | NA

20 participants

Evaluating the Feasibility and Preliminary Effects of BE+

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-08-15
Completion:: 2026-05-31

Conditions

Lung Cancer (Non-Small Cell)
Self-management Behavior
Physical Activity
Stress
Quality of Life
Resistance Training

Interventions

BEHAVIORAL

No Results Yet

NCT07214415 | RECRUITING | PHASE2

54 participants

Veterans' Cognitive Function, Mental Health, and Quality of Life After Hyperbaric Oxygen Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-10-01
Completion:: 2026-09-15

Conditions

TBI Traumatic Brain Injury
PTSD - Post Traumatic Stress Disorder
Post Concussive Syndrome

Interventions

DRUG

No Results Yet

NCT07214402 | COMPLETED | NA

80 participants

Mediterranean Dietary Intervention on ROS Levels and TAC During Pregnancy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2023-03-06
Completion:: 2025-03-28

Conditions

Healthy Pregnant Women

Interventions

OTHER

No Results Yet

NCT07214363 | ACTIVE_NOT_RECRUITING | NA

20 participants

The Safety and Efficacy of Irreversible Electroporation for the Treatment of Perivascular Liver Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2023-10-01
Completion:: 2023-10-01

Conditions

Liver Cancer
Ablation Techniques
Radiology

Interventions

DEVICE

No Results Yet

NCT07214337 | NOT_YET_RECRUITING | NA

20 participants

Digital Inhaler Use in Obstructive Lung Disease Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-11-01
Completion:: 2027-01-31

Conditions

Chronic Obstructive Airways Disease Exacerbated
Chronic Obstructive Airway Disease

Interventions

DEVICE

No Results Yet

NCT07214246 | RECRUITING

100 participants

Follicular Fluid microRNAs in Ovarian Aging and Reproduction

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-09-22
Completion:: 2026-09-30

Conditions

Ovarian Aging
In Vitro Fertilisation (IVF) Treatment
InVitro Fertilization
In Vitro Fertilization Outcome

Interventions

OTHER

No Results Yet

NCT07214194 | NOT_YET_RECRUITING | NA

150 participants

Vagus Nerve Stimulation to Enhance Memory in Aging

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2027-02-28
Completion:: 2028-07-31

Conditions

Alzheimer Disease
Aging

Interventions

DEVICE

No Results Yet

NCT07214181 | COMPLETED

30 participants

Topical Amitriptyline 1% Gel for the Treatment of Burning Mouth Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2024-01-02
Completion:: 2024-11-30

Conditions

Burning Mouth Syndrome
Stomatodynia

Interventions

DRUG

No Results Yet

NCT07214142 | NOT_YET_RECRUITING | PHASE2

30 participants

Total Neoadjuvant Therapy With PD-1 for Locally Advcancer Rectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-10-01
Completion:: 2027-12-31

Conditions

Rectal Cancer Patients

Interventions

DRUG

No Results Yet

NCT07214129 | COMPLETED | NA

20 participants

Safety and Efficacy of Nebulized Nitroglycerin in Pulmonary Arterial Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2022-03-01
Completion:: 2023-03-01

Conditions

Pulmonary Arterial Hypertension

Interventions

DRUG

No Results Yet

NCT07214116 | NOT_YET_RECRUITING | NA

175 participants

Virtual Reality, Music, and Education to Reduce Anxiety in Patients Undergoing Ingrown Toenail Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-10-31
Completion:: 2027-01-31

Conditions

Ingrown Toenail

Interventions

BEHAVIORAL
DEVICE

No Results Yet

NCT07214090 | NOT_YET_RECRUITING

40 participants

Pilot Study Evaluating the Therapeutic Effects of Passive Exposure Virtual Reality on Pain, Anxiety, Fatigue, and Well-being in Patients With Complex Palliative Care Needs.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-10-01
Completion:: 2026-05-01

Conditions

Palliative Care

Interventions

BEHAVIORAL

No Results Yet

NCT07214064 | NOT_YET_RECRUITING | PHASE2

27 participants

Venetoclax- Augmented Treosulfan-Based Reduced Intensity Conditioning Before Allogeneic Stem Cell Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2026-01-31
Completion:: 2027-08-31

Conditions

AML (Acute Myeloid Leukemia)
MDS/AML
MDS (Myelodysplastic Syndrome)

Interventions

DRUG

No Results Yet

NCT07214051 | COMPLETED | NA

500 participants

PR-CEAL: Community Outreach Engagement Group

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2023-12-13
Completion:: 2024-07-12

Conditions

Breast Cancer Prevention
Colorectal Cancer Prevention
Cervical Cancer Prevention

Interventions

BEHAVIORAL

No Results Yet

NCT07214025 | NOT_YET_RECRUITING

100 participants

Safety and Efficacy of Romiplostim in Treatment of Chronic ITP in Children

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-11-01
Completion:: 2026-11-01

Conditions

Romiplostim N01
ITP

Interventions

DRUG

No Results Yet

NCT07213999 | COMPLETED | NA

1 participants

Novel DBS Device in Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2022-07-01
Completion:: 2022-07-02

Conditions

Parkinson's Disease (PD)

Interventions

DEVICE

No Results Yet

NCT07213895 | COMPLETED | PHASE1

14 participants

Bioequivalence Study to Compare Empagliflozin/Linagliptin/Metformin HCL 25mg/5mg/1000mg Extended-Release Tablets Versus Trijardy® XR Extended Release Film Coated Tablets

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-05-21
Completion:: 2025-09-15

Conditions

Type 2 Diabetes Mellitus (T2DM)

Interventions

DRUG

No Results Yet

NCT07213882 | NOT_YET_RECRUITING | EARLY_PHASE1

30 participants

A Phase 1, Multicenter, Open-label, Prospective, First-in-human Dose-escalation Clinical Trial of Domain Therapeutics' Anti-CCR8 Monoclonal Antibody (DT-7012) in Patients With Relapsed or Refractory Cutaneous T-cell Lymphomas (CTCL)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2026-01-01
Completion:: 2028-08-01

Conditions

Cutaneous T Cell Lymphoma (CTCL)
Mycosis Fungoides
Sezary Syndrome

Interventions

DRUG

No Results Yet

NCT07213869 | NOT_YET_RECRUITING | NA

5 participants

Alpha tACS for Disorders of Consciousness : a Single Case Experimental Design

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2026-01-01
Completion:: 2028-06-01

Conditions

Disorder of Consciousness

Interventions

DEVICE

No Results Yet

NCT07213843 | NOT_YET_RECRUITING | NA

60 participants

Combined Circulatory and Dietary Interventions for Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2026-10-01
Completion:: 2028-10-01

Conditions

Diabete Type 2
Neuropathy, Painful

Interventions

OTHER

No Results Yet

NCT07213765 | RECRUITING | PHASE4

188 participants

Short-term Antibiotic Therapy in Mycobacterium Avium Complex Pulmonary Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-07-24
Completion:: 2028-09-30

Conditions

Mycobacterium Avium Complex Pulmonary Disease

Interventions

DRUG

No Results Yet

NCT07213752 | COMPLETED | NA

33 participants

Diode Laser-Assisted Periodontal Therapy Enhances Clinical Outcomes for Deep Periodontal Pockets in Smokers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2023-12-10
Completion:: 2025-01-21

Conditions

Periodontitis
Periodontitis Stage III
Periodontal Disease
Diode Laser Therapy
Smoking
Malondialdehyde

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT07213739 | NOT_YET_RECRUITING | NA

20 participants

A Trial to Investigate the New Caulis Pro® Low Air Loss (LAL) System

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-09-30
Completion:: 2026-03-30

Conditions

Health Adult Subjects
Pressure Injury Prevention

Interventions

DEVICE

No Results Yet

NCT07213713 | NOT_YET_RECRUITING

80 participants

Evaluation of Anti-Xa Activity in Patients With Severe Obesity After Subcutaneous Injection of Enoxaparin for Antithrombotic Prophylaxis at Two Different Sites.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-10-01
Completion:: 2027-10-01

Conditions

Venous Thromboembolism
Obese Patients

No Results Yet

NCT07213622 | ENROLLING_BY_INVITATION | NA

100 participants

The Use of Smart Glasses for Saphenous Nerve Adductor Canal Block

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2024-03-04
Completion:: 2025-12-31

Conditions

Total Knee Arthroplasty

Interventions

PROCEDURE

No Results Yet

NCT07213596 | NOT_YET_RECRUITING | NA

100 participants

Virtual Reality Treatment for Trauma Related to COVID-19 Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-11-01
Completion:: 2026-12-31

Conditions

PTSD
PTSD Symptoms

Interventions

BEHAVIORAL

No Results Yet

NCT07213531 | RECRUITING

21000 participants

Enhanced Valves Interventions and Safe AI Generated End Results

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2024-05-01
Completion:: 2028-05-31

Conditions

Heart Valve Disease
TAVI
M-TEER
TTVI
TMVI
T-TEER
Mitraclip
TriClip

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07213518 | COMPLETED | NA

108 participants

High Velocity Nasal Insufflation Versus Continuous Positive Airway Pressure in COVID 19 Pneumonic Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2022-01-01
Completion:: 2022-07-01

Conditions

COVID-19 Pneumonia

Interventions

DEVICE

No Results Yet

NCT07212010 | ENROLLING_BY_INVITATION

600 participants

Neurodevelopmental Outcomes in Cerebral Visual Impairment

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-07-31
Completion:: 2030-08-31

Conditions

Cerebral Visual Impairment

No Results Yet

NCT07209085 | NOT_YET_RECRUITING | NA

110 participants

A Study to Evaluate the Safety and Effectiveness of the FastWave Artero™ Peripheral Intravascular Lithotripsy (IVL) System in Adults With Peripheral Artery Disease (PAD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-12-31
Completion:: 2026-09-30

Conditions

Peripheral Artery Disease (PAD)

Interventions

DEVICE

No Results Yet

NCT07188467 | RECRUITING | NA

50 participants

Testing Adapted Self-Help Plus (SH+) for Stress and Well-Being in International Students at a U.S. University

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-10-07
Completion:: 2025-12-31

Conditions

Stress, Psychological
Depression and/or Anxiety in the Mild-to-moderate Range
Loneliness
Adjustment, Psychological

Interventions

BEHAVIORAL

No Results Yet

NCT07176416 | RECRUITING

50 participants

Effective Phaco Time and Endothelial Cell Loss When Using Veritas

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-10-03
Completion:: 2026-10-01

Conditions

Cataract

Interventions

DEVICE

No Results Yet

NCT07145112 | RECRUITING | PHASE1

20 participants

Laser Interstitial Thermal Therapy (LITT) and Lomustine (CCNU) for Recurrent Glioblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-10-01
Completion:: 2027-07-31

Conditions

Glioblastoma

Interventions

PROCEDURE
DRUG

No Results Yet