Clinical Trials Updated in 2025

NCT05300022 | WITHDRAWN | NA

0 participants

Technology Knowledge Optimization in Type 1 Diabetes (TeKnO T1D): Parents

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-08-15
Completion:: 2027-07-31

Conditions

Type 1 Diabetes

Interventions

OTHER

No Results Yet

NCT05279742 | ENROLLING_BY_INVITATION | PHASE1/PHASE2

60 participants

Enhancing the Natriuretic Peptide System in HFpEF

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2022-11-04
Completion:: 2027-04-30

Conditions

Heart Failure With Preserved Ejection Fraction
Chronic Kidney Diseases

Interventions

DRUG

No Results Yet

NCT05270057 | ACTIVE_NOT_RECRUITING | PHASE1

11 participants

Loncastuximab Tesirine in Combination With DA-EPOCH-R in Patients With Previously Untreated Aggressive B-cell Lymphoid Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2023-01-26
Completion:: 2025-05-28

Conditions

B-cell Lymphoma
Burkitt Lymphoma

Interventions

DRUG

No Results Yet

NCT05203965 | RECRUITING | EARLY_PHASE1

80 participants

Functional Neuroimaging of Alcoholism Vulnerability: Probing Glutamate and Reward, Using the mGluR5 Inhibitor Mavoglurant

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2022-05-17
Completion:: 2026-07-31

Conditions

Familial Alcoholism Vulnerability

Interventions

DRUG

No Results Yet

NCT05195489 | COMPLETED | NA

28 participants

Examining the Impact of Family Connectors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2022-03-07
Completion:: 2024-10-31

Conditions

Caregiver Stress Syndrome

Interventions

OTHER

Results Available

NCT05115513 | COMPLETED | PHASE1

41 participants

Standardized Field Test for Marijuana Impairment II

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2022-08-25
Completion:: 2023-08-21

Conditions

Marijuana Impairment

Interventions

DRUG

No Results Yet

NCT05062369 | RECRUITING | NA

40 participants

Tdcs And cogNitive traininG cOmbined for AUD (TANGO)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2022-03-03
Completion:: 2027-09-30

Conditions

Alcohol Use Disorder
Addiction

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT05014087 | TERMINATED | PHASE2

23 participants

Digoxin In Treatment of Alcohol Associated Hepatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2021-10-08
Completion:: 2025-06-22

Conditions

Acute Alcoholic Hepatitis
Chemical and Drug Induced Liver Injury
Alcohol-Induced Disorders
Steatohepatitis Caused by Ingestible Alcohol

Interventions

DRUG

No Results Yet

NCT05014074 | NOT_YET_RECRUITING | NA

10 participants

The Dreamer Girls Project: Adaptation of SISTA/SIHLE for HIV/AIDS and Substance Abuse Prevention Among Black Adolescent Girls

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2026-01-31
Completion:: 2026-05-31

Conditions

HIV/AIDS

Interventions

OTHER

No Results Yet

NCT04947527 | COMPLETED | PHASE2

274 participants

Efficacy and Safety Evaluation of Anti-Caries Varnish

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2022-06-04
Completion:: 2024-06-19

Conditions

Dental Caries in Children

Interventions

DRUG

Results Available

NCT04931654 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

136 participants

A Study to Assess the Safety and Efficacy of AZD7789 in Participants With Advanced or Metastatic Solid Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2021-09-28
Completion:: 2024-12-04

Conditions

Carcinoma, Non-Small-Cell Lung
Gastric Cancer
Gastroesophageal Junction Cancer

Interventions

DRUG

No Results Yet

NCT04873232 | COMPLETED | PHASE3

106 participants

A 6-Month Extension Study of VMDN-003-2 to Assess Engensis in Participants With Painful Diabetic Peripheral Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2021-05-17
Completion:: 2023-09-14

Conditions

Diabetic Peripheral Neuropathy

Interventions

BIOLOGICAL
OTHER

Results Available

NCT04812548 | TERMINATED | PHASE2

20 participants

A Study of Sabatolimab in Combination With Azacitidine and Venetoclax in High or Very High Risk MDS Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2021-05-31
Completion:: 2023-05-08

Conditions

Myelodysplastic Syndrome (MDS)

Interventions

DRUG

Results Available

NCT04810078 | ACTIVE_NOT_RECRUITING | PHASE3

681 participants

A Study of Subcutaneous Nivolumab Versus Intravenous Nivolumab in Participants With Previously Treated Clear Cell Renal Cell Carcinoma That is Advanced or Has Spread

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2021-05-21
Completion:: 2025-07-29

Conditions

Clear Cell Renal Cell Carcinoma

Interventions

BIOLOGICAL

No Results Yet

NCT04747626 | RECRUITING | NA

590 participants

B-SAFER: Branched Stented Anastomosis Frozen Elephant Trunk Repair

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2021-03-25
Completion:: 2030-12-31

Conditions

Thoracic Aortic Aneurysm
Aortic Dissection
Congenital Aortic Anomaly

Interventions

DEVICE

No Results Yet

NCT04572841 | COMPLETED | PHASE2

84 participants

Safety, Tolerability, Pharmacokinetics, and Therapeutic Efficacy of SAR441344 in Primary Sjögren's Syndrome (pSjS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-11-12
Completion:: 2023-11-08

Conditions

Sjögren's Syndrome
Sjogren's Syndrome

Interventions

DRUG

Results Available

NCT04549532 | COMPLETED | NA

169 participants

Targeted Multidomain (T-MD) Interventions for Complex Mild Traumatic Brain Injury (mTBI)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2021-06-15
Completion:: 2024-04-30

Conditions

Concussion, Mild

Interventions

BEHAVIORAL

No Results Yet

NCT04494256 | TERMINATED | PHASE1/PHASE2

99 participants

A Study to Assess the Safety, Tolerability, and Effect on Disease Progression of BIIB105 in Participants With Amyotrophic Lateral Sclerosis (ALS) and Participants With the ALS Ataxin-2 (ATXN2) Genetic Mutation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-09-28
Completion:: 2024-08-13

Conditions

Amyotrophic Lateral Sclerosis

Interventions

DRUG

Results Available

NCT04469270 | COMPLETED | PHASE3

162 participants

Study to Assess Safety and Efficacy of Engensis in Painful Diabetic Peripheral Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-11-20
Completion:: 2023-03-24

Conditions

Diabetic Neuropathy, Painful

Interventions

BIOLOGICAL
OTHER

Results Available

NCT04363801 | TERMINATED | PHASE2

247 participants

A Study of DKN-01 in Combination With Tislelizumab ± Chemotherapy in Patients With Gastric or Gastroesophageal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-07-29
Completion:: 2025-03-31

Conditions

Gastric Cancer
Gastric Adenocarcinoma
GastroEsophageal Cancer

Interventions

DRUG

Results Available

NCT04169711 | COMPLETED | PHASE1

26 participants

Study of ARO-HIF2 in Patients With Advanced Clear Cell Renal Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-08-17
Completion:: 2022-01-24

Conditions

Clear Cell Renal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT04164225 | RECRUITING | NA

60 participants

Feasibility of Identifying Brain Mechanisms of Qigong and Behavioral Outcomes After Qigong Practice in People With Chronic Low Back Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-01-21
Completion:: 2028-06-30

Conditions

Low Back Pain

Interventions

BEHAVIORAL

No Results Yet

NCT04101539 | COMPLETED | NA

67 participants

Comparing Pulmonary Vein Isolation to Pulmonary Vein Isolation + OPTIMA Ablation in Patients Undergoing Ablation for Atrial Fibrillation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2019-09-01
Completion:: 2025-09-30

Conditions

Atrial Fibrillation Chronic

Interventions

DEVICE

No Results Yet

NCT04055090 | COMPLETED | PHASE3

101 participants

Extension of Phase 3 Gene Therapy for Painful Diabetic Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2019-02-04
Completion:: 2019-07-24

Conditions

Painful Diabetic Neuropathy
Diabetic Neuropathy, Painful

Interventions

GENETIC
DRUG

Results Available

NCT04023110 | COMPLETED | PHASE1

68 participants

Risk-Guided Cardioprotection With Carvedilol in Breast Cancer Patients Treated With Doxorubicin and/or Trastuzumab

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2019-08-09
Completion:: 2024-08-31

Conditions

Cardiotoxicity
Risk Factor, Cardiovascular
Toxicity Due to Chemotherapy
Breast Cancer
Cardiomyopathies
Heart Failure

Interventions

DRUG

Results Available

NCT04018092 | ACTIVE_NOT_RECRUITING | PHASE2

168 participants

The Revitalize Study in Older Adults at Risk for Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-08-12
Completion:: 2024-08-07

Conditions

Cognitive Aging
Alzheimer Disease, Protection Against

Interventions

DEVICE

Results Available

NCT04009044 | ACTIVE_NOT_RECRUITING | PHASE2

156 participants

Topical Afimoxifene in Treating Patients With Breast Cancer Who Have Undergone Radiation Therapy on One Breast

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-02-17
Completion:: 2026-01-31

Conditions

Cancer Survivor
Ductal Breast Carcinoma In Situ
Invasive Breast Carcinoma

Interventions

DRUG
PROCEDURE
OTHER

No Results Yet

NCT03819088 | COMPLETED | NA

17 participants

Effects on Quality of Life With Zinc Supplementation in Patients With Gastrointestinal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2019-04-17
Completion:: 2021-10-05

Conditions

Gastric Carcinoma
Liver and Intrahepatic Bile Duct Carcinoma
Unresectable Esophageal Carcinoma
Unresectable Pancreatic Carcinoma

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT03522142 | TERMINATED | PHASE1

83 participants

A Study Exploring the Safety and Tolerability of INCB081776 in Participants With Advanced Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2018-08-27
Completion:: 2025-09-10

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT03464097 | TERMINATED | PHASE3

550 participants

A Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2018-06-27
Completion:: 2024-10-03

Conditions

Crohn Disease

Interventions

DRUG
OTHER

Results Available

NCT03454828 | COMPLETED | NA

38 participants

Mechanisms of Obesity and Its Metabolic Complications in Youth

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2018-08-18
Completion:: 2024-06-30

Conditions

Obesity, Childhood

Interventions

DIETARY_SUPPLEMENT

Results Available

NCT03184870 | COMPLETED | PHASE1/PHASE2

332 participants

A Study of BMS-813160 in Combination With Chemotherapy or Nivolumab in Participants With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2017-08-08
Completion:: 2023-04-06

Conditions

Colorectal Cancer
Pancreatic Cancer

Interventions

DRUG
BIOLOGICAL

Results Available

NCT03164564 | ACTIVE_NOT_RECRUITING | PHASE3

3224 participants

Evaluating the Safety and Efficacy of Long-Acting Injectable Cabotegravir Compared to Daily Oral TDF/FTC for Pre-Exposure Prophylaxis in HIV-Uninfected Women

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2017-11-07
Completion:: 2020-11-05

Conditions

HIV Infections

Interventions

DRUG

Results Available

NCT02978144 | TERMINATED | PHASE2

34 participants

Lung Imaging of Apoptosis in Chronic Obstructive Pulmonary Disease (COPD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2017-06-15
Completion:: 2019-10-08

Conditions

Chronic Obstructive Pulmonary Disease (COPD)

Interventions

DRUG

Results Available

NCT02928185 | COMPLETED

41 participants

Adaptation of Skills Training Manuals for Patients Receiving Hematopoietic Stem Cell Transplantation and Their Caregivers

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2016-09-13
Completion:: 2025-10-07

Conditions

Post Hematopoietic Stem Cell Transplantation

Interventions

BEHAVIORAL

No Results Yet

NCT02849223 | ACTIVE_NOT_RECRUITING | PHASE2

41 participants

Transcranial Direct Current Stimulation (TDCS) as an Intervention for Patients With Traumatic Brain Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2016-07-31
Completion:: 2026-09-30

Conditions

Traumatic Brain Injury

Interventions

DEVICE

No Results Yet

NCT02783664 | ACTIVE_NOT_RECRUITING

164 participants

Evaluating the Effects of Genetic Testing on Patients' Stress Levels

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2016-07-31
Completion:: 2027-07-31

Conditions

Breast Cancer

Interventions

OTHER

No Results Yet

NCT02563522 | TERMINATED | PHASE3

44 participants

Safety and Efficacy Study of Engensis (VM202) in the Treatment of Chronic Non-Healing Foot Ulcers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2017-06-27
Completion:: 2019-09-24

Conditions

Foot Ulcer, Diabetic

Interventions

GENETIC
DRUG

Results Available

NCT02513303 | COMPLETED | PHASE3

269 participants

Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2015-11-30
Completion:: 2021-06-30

Conditions

Complication of Renal Dialysis
End Stage Renal Disease
End Stage Kidney Disease
ESRD
Chronic Kidney Failure
Complication of Hemodialysis
Vascular Access Complication
Arteriovenous Fistula

Interventions

DRUG
PROCEDURE
DEVICE

Results Available

NCT02500849 | ACTIVE_NOT_RECRUITING | PHASE1

12 participants

Safety Study of Zinc Finger Nuclease CCR5-modified Hematopoietic Stem/Progenitor Cells in HIV-1 Infected Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2016-03-10
Completion:: 2026-08-24

Conditions

HIV

Interventions

GENETIC

No Results Yet