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Transcranial Direct Current Stimulation (TDCS) as an Intervention for Patients With Traumatic Brain Injury

NCT02849223 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 41

Last updated 2025-10-09

No results posted yet for this study

Summary

The primary aim of this study is to assess the magnitude of transcranial direct current stimulation (tDCS) -induced cognitive and functional change in patients with mild traumatic brain injury. This study will also attempt to identify biomarkers associated with treatment response. Last, acceptability and tolerability of procedures will be assessed. To accomplish these aims, a randomized, double-blind, sham-controlled, parallel groups, pilot study will be conducted in which participants are assigned to 24 sessions of tDCS or sham stimulation offered concurrent with working memory training. Neural efficiency will be measured with electroencephalogram (EEG) pre and post-intervention.

Conditions

Interventions

DEVICE

Anodal Transcranial Direct Current Stimulation

2 milliamps (mA) of anodal stimulation will be applied to the left dorsal lateral cortex for 20 minutes concurrent with working memory training.

DEVICE

Sham stimulation

30 seconds of anodal TDCS stimulation will be applied to the left dorsal lateral cortex concurrent with working memory training

Sponsors & Collaborators

  • State of Minnesota

    collaborator UNKNOWN

  • Minnesota Veterans Medical Research and Education Foundation

    collaborator OTHER

  • Minneapolis Veterans Affairs Medical Center

    lead FED

Principal Investigators

  • Tasha M Nienow, PhD · Minneapolis Veteran Affairs Health Care System

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-07-31
Primary Completion
2026-09-30
Completion
2026-09-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02849223 on ClinicalTrials.gov