Clinical Trials

NCT05922995 | TERMINATED | EARLY_PHASE1

20 participants

The Effects of Tasimelteon in Participants With REM Behavior Disorder (RBD)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2023-09-30

Completion:

2023-12-01

Conditions

• REM Behavior Disorder

Interventions

• DRUG

No Results Yet

NCT05852145 | RECRUITING | PHASE1/PHASE2

52 participants

Oral Changes With Caloric and no Caloric Sweeteners

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2025-08-01

Completion:

2025-12-31

Conditions

• pH
• Microbiome
• Dental Plaque

Interventions

• DRUG
• OTHER

No Results Yet

NCT05754333 | COMPLETED | PHASE3

107 participants

A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2023-08-02

Completion:

2024-12-17

Conditions

• Intraoperative Ureter Visualization
• Abdominolpelvic Surgery

Interventions

• DRUG

Results Available

NCT05711485 | RECRUITING | NA

132 participants

Platelet-Directed Whole Blood Transfusion Strategy for Malaria

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2024-02-24

Completion:

2027-04-30

Conditions

• Severe Malaria
• Thrombocytopenia

Interventions

• OTHER

No Results Yet

NCT05691023 | ACTIVE_NOT_RECRUITING

50 participants

VNS-REHAB At-Home - Post-Market Study for Using the Vivistim System® at Home

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-09

Start Date:

2023-06-01

Completion:

2026-12-31

Conditions

• Ischemic Stroke
• Upper Extremity Problem

Interventions

• DEVICE

No Results Yet

NCT05669833 | RECRUITING | PHASE3

63 participants

Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2023-07-14

Completion:

2026-10-31

Conditions

• Psoriatic Arthritis

Interventions

• DRUG

No Results Yet

NCT05599945 | COMPLETED | PHASE1

48 participants

First Human Dose Trial for a New Medication to Potentially Treat Liver Diseases

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2022-11-23

Completion:

2025-08-29

Conditions

• Healthy Volunteers
• Hepatic Steatosis

Interventions

• DRUG

No Results Yet

NCT05559099 | COMPLETED | PHASE2

597 participants

Tecovirimat for Treatment of Monkeypox Virus

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2022-10-10

Completion:

2024-09-03

Conditions

• Monkeypox

Interventions

• DRUG

Results Available

NCT05540782 | ACTIVE_NOT_RECRUITING

200 participants

A Study of Cognitive Health in Survivors of Prostate Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-09

Start Date:

2022-09-08

Completion:

2026-09-08

Conditions

• Prostate Cancer
• Survivorship

Interventions

• BEHAVIORAL

No Results Yet

NCT05514444 | COMPLETED | PHASE1

64 participants

Study of MK-4464 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced/Metastatic Solid Tumors (MK-4464-001)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2022-09-25

Completion:

2025-09-18

Conditions

• Advanced/Metastatic Solid Tumors
• Neoplasms

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05496374 | COMPLETED | PHASE2

25 participants

A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SPR720 as Compared With Placebo for the Treatment of Participants With Mycobacterium Avium Complex (MAC) Pulmonary Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2022-12-14

Completion:

2024-10-08

Conditions

• Nontuberculous Mycobacterial Pulmonary Disease (NTM-PD)

Interventions

• DRUG

No Results Yet

NCT05491538 | RECRUITING | NA

20 participants

Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2022-12-01

Completion:

2026-11-27

Conditions

• Schizophrenia
• Bipolar Disorder
• Depressive Disorder, Major
• Stress Disorder, Post-Traumatic

Interventions

• BEHAVIORAL

No Results Yet

NCT05444049 | COMPLETED | NA

6 participants

NEURESCUE Device as an Adjunct to In-Hospital Cardiac Arrest (ARISE)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2022-12-08

Completion:

2024-09-30

Conditions

• Cardiac Arrest
• Cardiopulmonary Arrest
• Cardiovascular Diseases

Interventions

• DEVICE

No Results Yet

NCT05437510 | COMPLETED | PHASE3

8057 participants

Study of a Single Intramuscular Dose of Nirsevimab in the Prevention of Hospitalizations Due to Respiratory Syncytial Virus (RSV) Infection in Healthy Term and Preterm Infants During the First Year of Life

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2022-08-08

Completion:

2024-03-27

Conditions

• RSV Immunization
• Healthy Volunteer

Interventions

• BIOLOGICAL

Results Available

NCT05385497 | COMPLETED | NA

10 participants

Combining Aerobic Exercise and Virtual Reality for Cognitive-motor Rehabilitation in PD

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2022-11-07

Completion:

2023-07-15

Conditions

• Parkinson's Disease

Interventions

• OTHER
• DEVICE

No Results Yet

NCT05370521 | TERMINATED | PHASE2

27 participants

A Study of Safety and Efficacy of Tildacerfont in Females With Polycystic Ovary Syndrome and Elevated Adrenal Androgens

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2022-05-15

Completion:

2023-08-03

Conditions

• Polycystic Ovary Syndrome

Interventions

• DRUG

Results Available

NCT05321368 | RECRUITING | NA

425 participants

A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2023-10-16

Completion:

2026-10-21

Conditions

• Hypertension
• High Blood Pressure
• Diabetes
• Chronic Kidney Diseases

Interventions

• BEHAVIORAL

No Results Yet

NCT05306210 | COMPLETED

1029 participants

Forxiga CKD Japan Post-Marketing Surveillance (PMS)

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-09

Start Date:

2022-04-12

Completion:

2024-10-08

Conditions

• Chronic Kidney Disease

No Results Yet

NCT05300022 | WITHDRAWN | NA

0 participants

Technology Knowledge Optimization in Type 1 Diabetes (TeKnO T1D): Parents

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2025-08-15

Completion:

2027-07-31

Conditions

• Type 1 Diabetes

Interventions

• OTHER

No Results Yet

NCT05279742 | ENROLLING_BY_INVITATION | PHASE1/PHASE2

60 participants

Enhancing the Natriuretic Peptide System in HFpEF

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2022-11-04

Completion:

2027-04-30

Conditions

• Heart Failure With Preserved Ejection Fraction
• Chronic Kidney Diseases

Interventions

• DRUG

No Results Yet

NCT05270057 | ACTIVE_NOT_RECRUITING | PHASE1

11 participants

Loncastuximab Tesirine in Combination With DA-EPOCH-R in Patients With Previously Untreated Aggressive B-cell Lymphoid Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2023-01-26

Completion:

2025-05-28

Conditions

• B-cell Lymphoma
• Burkitt Lymphoma

Interventions

• DRUG

No Results Yet

NCT05203965 | RECRUITING | EARLY_PHASE1

80 participants

Functional Neuroimaging of Alcoholism Vulnerability: Probing Glutamate and Reward, Using the mGluR5 Inhibitor Mavoglurant

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2022-05-17

Completion:

2026-07-31

Conditions

• Familial Alcoholism Vulnerability

Interventions

• DRUG

No Results Yet

NCT05195489 | COMPLETED | NA

28 participants

Examining the Impact of Family Connectors

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2022-03-07

Completion:

2024-10-31

Conditions

• Caregiver Stress Syndrome

Interventions

• OTHER

Results Available

NCT05115513 | COMPLETED | PHASE1

41 participants

Standardized Field Test for Marijuana Impairment II

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2022-08-25

Completion:

2023-08-21

Conditions

• Marijuana Impairment

Interventions

• DRUG

No Results Yet

NCT05062369 | RECRUITING | NA

40 participants

Tdcs And cogNitive traininG cOmbined for AUD (TANGO)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2022-03-03

Completion:

2027-09-30

Conditions

• Alcohol Use Disorder
• Addiction

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT05014087 | TERMINATED | PHASE2

23 participants

Digoxin In Treatment of Alcohol Associated Hepatitis

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2021-10-08

Completion:

2025-06-22

Conditions

• Acute Alcoholic Hepatitis
• Chemical and Drug Induced Liver Injury
• Alcohol-Induced Disorders
• Steatohepatitis Caused by Ingestible Alcohol

Interventions

• DRUG

No Results Yet

NCT05014074 | NOT_YET_RECRUITING | NA

10 participants

The Dreamer Girls Project: Adaptation of SISTA/SIHLE for HIV/AIDS and Substance Abuse Prevention Among Black Adolescent Girls

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2026-01-31

Completion:

2026-05-31

Conditions

• HIV/AIDS

Interventions

• OTHER

No Results Yet

NCT04947527 | COMPLETED | PHASE2

274 participants

Efficacy and Safety Evaluation of Anti-Caries Varnish

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2022-06-04

Completion:

2024-06-19

Conditions

• Dental Caries in Children

Interventions

• DRUG

Results Available

NCT04931654 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

136 participants

A Study to Assess the Safety and Efficacy of AZD7789 in Participants With Advanced or Metastatic Solid Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2021-09-28

Completion:

2024-12-04

Conditions

• Carcinoma, Non-Small-Cell Lung
• Gastric Cancer
• Gastroesophageal Junction Cancer

Interventions

• DRUG

No Results Yet

NCT04873232 | COMPLETED | PHASE3

106 participants

A 6-Month Extension Study of VMDN-003-2 to Assess Engensis in Participants With Painful Diabetic Peripheral Neuropathy

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2021-05-17

Completion:

2023-09-14

Conditions

• Diabetic Peripheral Neuropathy

Interventions

• BIOLOGICAL
• OTHER

Results Available

NCT04812548 | TERMINATED | PHASE2

20 participants

A Study of Sabatolimab in Combination With Azacitidine and Venetoclax in High or Very High Risk MDS Participants

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2021-05-31

Completion:

2023-05-08

Conditions

• Myelodysplastic Syndrome (MDS)

Interventions

• DRUG

Results Available

NCT04810078 | ACTIVE_NOT_RECRUITING | PHASE3

681 participants

A Study of Subcutaneous Nivolumab Versus Intravenous Nivolumab in Participants With Previously Treated Clear Cell Renal Cell Carcinoma That is Advanced or Has Spread

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2021-05-21

Completion:

2025-07-29

Conditions

• Clear Cell Renal Cell Carcinoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04747626 | RECRUITING | NA

590 participants

B-SAFER: Branched Stented Anastomosis Frozen Elephant Trunk Repair

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2021-03-25

Completion:

2030-12-31

Conditions

• Thoracic Aortic Aneurysm
• Aortic Dissection
• Congenital Aortic Anomaly

Interventions

• DEVICE

No Results Yet

NCT04572841 | COMPLETED | PHASE2

84 participants

Safety, Tolerability, Pharmacokinetics, and Therapeutic Efficacy of SAR441344 in Primary Sjögren's Syndrome (pSjS)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2020-11-12

Completion:

2023-11-08

Conditions

• Sjögren's Syndrome
• Sjogren's Syndrome

Interventions

• DRUG

Results Available

NCT04549532 | COMPLETED | NA

169 participants

Targeted Multidomain (T-MD) Interventions for Complex Mild Traumatic Brain Injury (mTBI)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2021-06-15

Completion:

2024-04-30

Conditions

• Concussion, Mild

Interventions

• BEHAVIORAL

No Results Yet

NCT04494256 | TERMINATED | PHASE1/PHASE2

99 participants

A Study to Assess the Safety, Tolerability, and Effect on Disease Progression of BIIB105 in Participants With Amyotrophic Lateral Sclerosis (ALS) and Participants With the ALS Ataxin-2 (ATXN2) Genetic Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2020-09-28

Completion:

2024-08-13

Conditions

• Amyotrophic Lateral Sclerosis

Interventions

• DRUG

Results Available

NCT04469270 | COMPLETED | PHASE3

162 participants

Study to Assess Safety and Efficacy of Engensis in Painful Diabetic Peripheral Neuropathy

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2020-11-20

Completion:

2023-03-24

Conditions

• Diabetic Neuropathy, Painful

Interventions

• BIOLOGICAL
• OTHER

Results Available

NCT04363801 | TERMINATED | PHASE2

247 participants

A Study of DKN-01 in Combination With Tislelizumab ± Chemotherapy in Patients With Gastric or Gastroesophageal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2020-07-29

Completion:

2025-03-31

Conditions

• Gastric Cancer
• Gastric Adenocarcinoma
• GastroEsophageal Cancer

Interventions

• DRUG

Results Available

NCT04169711 | COMPLETED | PHASE1

26 participants

Study of ARO-HIF2 in Patients With Advanced Clear Cell Renal Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2020-08-17

Completion:

2022-01-24

Conditions

• Clear Cell Renal Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT04164225 | RECRUITING | NA

60 participants

Feasibility of Identifying Brain Mechanisms of Qigong and Behavioral Outcomes After Qigong Practice in People With Chronic Low Back Pain

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-09

Start Date:

2020-01-21

Completion:

2028-06-30

Conditions

• Low Back Pain

Interventions

• BEHAVIORAL

No Results Yet