Clinical Trials Updated in 2025

NCT05321368 | RECRUITING | NA

425 participants

A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2023-10-16
Completion:: 2026-10-21

Conditions

Hypertension
High Blood Pressure
Diabetes
Chronic Kidney Diseases

Interventions

BEHAVIORAL

No Results Yet

NCT05306210 | COMPLETED

1029 participants

Forxiga CKD Japan Post-Marketing Surveillance (PMS)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2022-04-12
Completion:: 2024-10-08

Conditions

Chronic Kidney Disease

No Results Yet

NCT05300022 | WITHDRAWN | NA

0 participants

Technology Knowledge Optimization in Type 1 Diabetes (TeKnO T1D): Parents

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2025-08-15
Completion:: 2027-07-31

Conditions

Type 1 Diabetes

Interventions

OTHER

No Results Yet

NCT05279742 | ENROLLING_BY_INVITATION | PHASE1/PHASE2

60 participants

Enhancing the Natriuretic Peptide System in HFpEF

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2022-11-04
Completion:: 2027-04-30

Conditions

Heart Failure With Preserved Ejection Fraction
Chronic Kidney Diseases

Interventions

DRUG

No Results Yet

NCT05270057 | ACTIVE_NOT_RECRUITING | PHASE1

11 participants

Loncastuximab Tesirine in Combination With DA-EPOCH-R in Patients With Previously Untreated Aggressive B-cell Lymphoid Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2023-01-26
Completion:: 2025-05-28

Conditions

B-cell Lymphoma
Burkitt Lymphoma

Interventions

DRUG

No Results Yet

NCT05203965 | RECRUITING | EARLY_PHASE1

80 participants

Functional Neuroimaging of Alcoholism Vulnerability: Probing Glutamate and Reward, Using the mGluR5 Inhibitor Mavoglurant

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2022-05-17
Completion:: 2026-07-31

Conditions

Familial Alcoholism Vulnerability

Interventions

DRUG

No Results Yet

NCT05195489 | COMPLETED | NA

28 participants

Examining the Impact of Family Connectors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2022-03-07
Completion:: 2024-10-31

Conditions

Caregiver Stress Syndrome

Interventions

OTHER

Results Available

NCT05115513 | COMPLETED | PHASE1

41 participants

Standardized Field Test for Marijuana Impairment II

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2022-08-25
Completion:: 2023-08-21

Conditions

Marijuana Impairment

Interventions

DRUG

No Results Yet

NCT05062369 | RECRUITING | NA

40 participants

Tdcs And cogNitive traininG cOmbined for AUD (TANGO)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2022-03-03
Completion:: 2027-09-30

Conditions

Alcohol Use Disorder
Addiction

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT05014087 | TERMINATED | PHASE2

23 participants

Digoxin In Treatment of Alcohol Associated Hepatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2021-10-08
Completion:: 2025-06-22

Conditions

Acute Alcoholic Hepatitis
Chemical and Drug Induced Liver Injury
Alcohol-Induced Disorders
Steatohepatitis Caused by Ingestible Alcohol

Interventions

DRUG

No Results Yet

NCT05014074 | NOT_YET_RECRUITING | NA

10 participants

The Dreamer Girls Project: Adaptation of SISTA/SIHLE for HIV/AIDS and Substance Abuse Prevention Among Black Adolescent Girls

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2026-01-31
Completion:: 2026-05-31

Conditions

HIV/AIDS

Interventions

OTHER

No Results Yet

NCT04947527 | COMPLETED | PHASE2

274 participants

Efficacy and Safety Evaluation of Anti-Caries Varnish

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2022-06-04
Completion:: 2024-06-19

Conditions

Dental Caries in Children

Interventions

DRUG

Results Available

NCT04931654 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

136 participants

A Study to Assess the Safety and Efficacy of AZD7789 in Participants With Advanced or Metastatic Solid Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2021-09-28
Completion:: 2024-12-04

Conditions

Carcinoma, Non-Small-Cell Lung
Gastric Cancer
Gastroesophageal Junction Cancer

Interventions

DRUG

No Results Yet

NCT04873232 | COMPLETED | PHASE3

106 participants

A 6-Month Extension Study of VMDN-003-2 to Assess Engensis in Participants With Painful Diabetic Peripheral Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2021-05-17
Completion:: 2023-09-14

Conditions

Diabetic Peripheral Neuropathy

Interventions

BIOLOGICAL
OTHER

Results Available

NCT04812548 | TERMINATED | PHASE2

20 participants

A Study of Sabatolimab in Combination With Azacitidine and Venetoclax in High or Very High Risk MDS Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2021-05-31
Completion:: 2023-05-08

Conditions

Myelodysplastic Syndrome (MDS)

Interventions

DRUG

Results Available

NCT04810078 | ACTIVE_NOT_RECRUITING | PHASE3

681 participants

A Study of Subcutaneous Nivolumab Versus Intravenous Nivolumab in Participants With Previously Treated Clear Cell Renal Cell Carcinoma That is Advanced or Has Spread

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2021-05-21
Completion:: 2025-07-29

Conditions

Clear Cell Renal Cell Carcinoma

Interventions

BIOLOGICAL

No Results Yet

NCT04747626 | RECRUITING | NA

590 participants

B-SAFER: Branched Stented Anastomosis Frozen Elephant Trunk Repair

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2021-03-25
Completion:: 2030-12-31

Conditions

Thoracic Aortic Aneurysm
Aortic Dissection
Congenital Aortic Anomaly

Interventions

DEVICE

No Results Yet

NCT04572841 | COMPLETED | PHASE2

84 participants

Safety, Tolerability, Pharmacokinetics, and Therapeutic Efficacy of SAR441344 in Primary Sjögren's Syndrome (pSjS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-11-12
Completion:: 2023-11-08

Conditions

Sjögren's Syndrome
Sjogren's Syndrome

Interventions

DRUG

Results Available

NCT04549532 | COMPLETED | NA

169 participants

Targeted Multidomain (T-MD) Interventions for Complex Mild Traumatic Brain Injury (mTBI)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2021-06-15
Completion:: 2024-04-30

Conditions

Concussion, Mild

Interventions

BEHAVIORAL

No Results Yet

NCT04494256 | TERMINATED | PHASE1/PHASE2

99 participants

A Study to Assess the Safety, Tolerability, and Effect on Disease Progression of BIIB105 in Participants With Amyotrophic Lateral Sclerosis (ALS) and Participants With the ALS Ataxin-2 (ATXN2) Genetic Mutation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-09-28
Completion:: 2024-08-13

Conditions

Amyotrophic Lateral Sclerosis

Interventions

DRUG

Results Available

NCT04469270 | COMPLETED | PHASE3

162 participants

Study to Assess Safety and Efficacy of Engensis in Painful Diabetic Peripheral Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-11-20
Completion:: 2023-03-24

Conditions

Diabetic Neuropathy, Painful

Interventions

BIOLOGICAL
OTHER

Results Available

NCT04363801 | TERMINATED | PHASE2

247 participants

A Study of DKN-01 in Combination With Tislelizumab ± Chemotherapy in Patients With Gastric or Gastroesophageal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-07-29
Completion:: 2025-03-31

Conditions

Gastric Cancer
Gastric Adenocarcinoma
GastroEsophageal Cancer

Interventions

DRUG

Results Available

NCT04169711 | COMPLETED | PHASE1

26 participants

Study of ARO-HIF2 in Patients With Advanced Clear Cell Renal Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-08-17
Completion:: 2022-01-24

Conditions

Clear Cell Renal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT04164225 | RECRUITING | NA

60 participants

Feasibility of Identifying Brain Mechanisms of Qigong and Behavioral Outcomes After Qigong Practice in People With Chronic Low Back Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-01-21
Completion:: 2028-06-30

Conditions

Low Back Pain

Interventions

BEHAVIORAL

No Results Yet

NCT04101539 | COMPLETED | NA

67 participants

Comparing Pulmonary Vein Isolation to Pulmonary Vein Isolation + OPTIMA Ablation in Patients Undergoing Ablation for Atrial Fibrillation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2019-09-01
Completion:: 2025-09-30

Conditions

Atrial Fibrillation Chronic

Interventions

DEVICE

No Results Yet

NCT04055090 | COMPLETED | PHASE3

101 participants

Extension of Phase 3 Gene Therapy for Painful Diabetic Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2019-02-04
Completion:: 2019-07-24

Conditions

Painful Diabetic Neuropathy
Diabetic Neuropathy, Painful

Interventions

GENETIC
DRUG

Results Available

NCT04023110 | COMPLETED | PHASE1

68 participants

Risk-Guided Cardioprotection With Carvedilol in Breast Cancer Patients Treated With Doxorubicin and/or Trastuzumab

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2019-08-09
Completion:: 2024-08-31

Conditions

Cardiotoxicity
Risk Factor, Cardiovascular
Toxicity Due to Chemotherapy
Breast Cancer
Cardiomyopathies
Heart Failure

Interventions

DRUG

Results Available

NCT04018092 | ACTIVE_NOT_RECRUITING | PHASE2

168 participants

The Revitalize Study in Older Adults at Risk for Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-08-12
Completion:: 2024-08-07

Conditions

Cognitive Aging
Alzheimer Disease, Protection Against

Interventions

DEVICE

Results Available

NCT04009044 | ACTIVE_NOT_RECRUITING | PHASE2

156 participants

Topical Afimoxifene in Treating Patients With Breast Cancer Who Have Undergone Radiation Therapy on One Breast

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-02-17
Completion:: 2026-01-31

Conditions

Cancer Survivor
Ductal Breast Carcinoma In Situ
Invasive Breast Carcinoma

Interventions

DRUG
PROCEDURE
OTHER

No Results Yet

NCT03819088 | COMPLETED | NA

17 participants

Effects on Quality of Life With Zinc Supplementation in Patients With Gastrointestinal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2019-04-17
Completion:: 2021-10-05

Conditions

Gastric Carcinoma
Liver and Intrahepatic Bile Duct Carcinoma
Unresectable Esophageal Carcinoma
Unresectable Pancreatic Carcinoma

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT03522142 | TERMINATED | PHASE1

83 participants

A Study Exploring the Safety and Tolerability of INCB081776 in Participants With Advanced Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2018-08-27
Completion:: 2025-09-10

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT03464097 | TERMINATED | PHASE3

550 participants

A Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2018-06-27
Completion:: 2024-10-03

Conditions

Crohn Disease

Interventions

DRUG
OTHER

Results Available

NCT03454828 | COMPLETED | NA

38 participants

Mechanisms of Obesity and Its Metabolic Complications in Youth

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2018-08-18
Completion:: 2024-06-30

Conditions

Obesity, Childhood

Interventions

DIETARY_SUPPLEMENT

Results Available

NCT03184870 | COMPLETED | PHASE1/PHASE2

332 participants

A Study of BMS-813160 in Combination With Chemotherapy or Nivolumab in Participants With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2017-08-08
Completion:: 2023-04-06

Conditions

Colorectal Cancer
Pancreatic Cancer

Interventions

DRUG
BIOLOGICAL

Results Available

NCT03164564 | ACTIVE_NOT_RECRUITING | PHASE3

3224 participants

Evaluating the Safety and Efficacy of Long-Acting Injectable Cabotegravir Compared to Daily Oral TDF/FTC for Pre-Exposure Prophylaxis in HIV-Uninfected Women

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2017-11-07
Completion:: 2020-11-05

Conditions

HIV Infections

Interventions

DRUG

Results Available

NCT02978144 | TERMINATED | PHASE2

34 participants

Lung Imaging of Apoptosis in Chronic Obstructive Pulmonary Disease (COPD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2017-06-15
Completion:: 2019-10-08

Conditions

Chronic Obstructive Pulmonary Disease (COPD)

Interventions

DRUG

Results Available

NCT02928185 | COMPLETED

41 participants

Adaptation of Skills Training Manuals for Patients Receiving Hematopoietic Stem Cell Transplantation and Their Caregivers

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2016-09-13
Completion:: 2025-10-07

Conditions

Post Hematopoietic Stem Cell Transplantation

Interventions

BEHAVIORAL

No Results Yet

NCT02849223 | ACTIVE_NOT_RECRUITING | PHASE2

41 participants

Transcranial Direct Current Stimulation (TDCS) as an Intervention for Patients With Traumatic Brain Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2016-07-31
Completion:: 2026-09-30

Conditions

Traumatic Brain Injury

Interventions

DEVICE

No Results Yet

NCT02783664 | ACTIVE_NOT_RECRUITING

164 participants

Evaluating the Effects of Genetic Testing on Patients' Stress Levels

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2016-07-31
Completion:: 2027-07-31

Conditions

Breast Cancer

Interventions

OTHER

No Results Yet

NCT02563522 | TERMINATED | PHASE3

44 participants

Safety and Efficacy Study of Engensis (VM202) in the Treatment of Chronic Non-Healing Foot Ulcers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2017-06-27
Completion:: 2019-09-24

Conditions

Foot Ulcer, Diabetic

Interventions

GENETIC
DRUG

Results Available