Clinical Trials Updated in 2025

NCT04101539 | COMPLETED | NA

67 participants

Comparing Pulmonary Vein Isolation to Pulmonary Vein Isolation + OPTIMA Ablation in Patients Undergoing Ablation for Atrial Fibrillation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2019-09-01
Completion:: 2025-09-30

Conditions

Atrial Fibrillation Chronic

Interventions

DEVICE

No Results Yet

NCT04055090 | COMPLETED | PHASE3

101 participants

Extension of Phase 3 Gene Therapy for Painful Diabetic Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2019-02-04
Completion:: 2019-07-24

Conditions

Painful Diabetic Neuropathy
Diabetic Neuropathy, Painful

Interventions

GENETIC
DRUG

Results Available

NCT04023110 | COMPLETED | PHASE1

68 participants

Risk-Guided Cardioprotection With Carvedilol in Breast Cancer Patients Treated With Doxorubicin and/or Trastuzumab

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2019-08-09
Completion:: 2024-08-31

Conditions

Cardiotoxicity
Risk Factor, Cardiovascular
Toxicity Due to Chemotherapy
Breast Cancer
Cardiomyopathies
Heart Failure

Interventions

DRUG

Results Available

NCT04018092 | ACTIVE_NOT_RECRUITING | PHASE2

168 participants

The Revitalize Study in Older Adults at Risk for Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-08-12
Completion:: 2024-08-07

Conditions

Cognitive Aging
Alzheimer Disease, Protection Against

Interventions

DEVICE

Results Available

NCT04009044 | ACTIVE_NOT_RECRUITING | PHASE2

156 participants

Topical Afimoxifene in Treating Patients With Breast Cancer Who Have Undergone Radiation Therapy on One Breast

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2020-02-17
Completion:: 2026-01-31

Conditions

Cancer Survivor
Ductal Breast Carcinoma In Situ
Invasive Breast Carcinoma

Interventions

DRUG
PROCEDURE
OTHER

No Results Yet

NCT03819088 | COMPLETED | NA

17 participants

Effects on Quality of Life With Zinc Supplementation in Patients With Gastrointestinal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2019-04-17
Completion:: 2021-10-05

Conditions

Gastric Carcinoma
Liver and Intrahepatic Bile Duct Carcinoma
Unresectable Esophageal Carcinoma
Unresectable Pancreatic Carcinoma

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT03522142 | TERMINATED | PHASE1

83 participants

A Study Exploring the Safety and Tolerability of INCB081776 in Participants With Advanced Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2018-08-27
Completion:: 2025-09-10

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT03464097 | TERMINATED | PHASE3

550 participants

A Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2018-06-27
Completion:: 2024-10-03

Conditions

Crohn Disease

Interventions

DRUG
OTHER

Results Available

NCT03454828 | COMPLETED | NA

38 participants

Mechanisms of Obesity and Its Metabolic Complications in Youth

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2018-08-18
Completion:: 2024-06-30

Conditions

Obesity, Childhood

Interventions

DIETARY_SUPPLEMENT

Results Available

NCT03184870 | COMPLETED | PHASE1/PHASE2

332 participants

A Study of BMS-813160 in Combination With Chemotherapy or Nivolumab in Participants With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2017-08-08
Completion:: 2023-04-06

Conditions

Colorectal Cancer
Pancreatic Cancer

Interventions

DRUG
BIOLOGICAL

Results Available

NCT03164564 | ACTIVE_NOT_RECRUITING | PHASE3

3224 participants

Evaluating the Safety and Efficacy of Long-Acting Injectable Cabotegravir Compared to Daily Oral TDF/FTC for Pre-Exposure Prophylaxis in HIV-Uninfected Women

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2017-11-07
Completion:: 2020-11-05

Conditions

HIV Infections

Interventions

DRUG

Results Available

NCT02978144 | TERMINATED | PHASE2

34 participants

Lung Imaging of Apoptosis in Chronic Obstructive Pulmonary Disease (COPD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2017-06-15
Completion:: 2019-10-08

Conditions

Chronic Obstructive Pulmonary Disease (COPD)

Interventions

DRUG

Results Available

NCT02928185 | COMPLETED

41 participants

Adaptation of Skills Training Manuals for Patients Receiving Hematopoietic Stem Cell Transplantation and Their Caregivers

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2016-09-13
Completion:: 2025-10-07

Conditions

Post Hematopoietic Stem Cell Transplantation

Interventions

BEHAVIORAL

No Results Yet

NCT02849223 | ACTIVE_NOT_RECRUITING | PHASE2

41 participants

Transcranial Direct Current Stimulation (TDCS) as an Intervention for Patients With Traumatic Brain Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2016-07-31
Completion:: 2026-09-30

Conditions

Traumatic Brain Injury

Interventions

DEVICE

No Results Yet

NCT02783664 | ACTIVE_NOT_RECRUITING

164 participants

Evaluating the Effects of Genetic Testing on Patients' Stress Levels

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2016-07-31
Completion:: 2027-07-31

Conditions

Breast Cancer

Interventions

OTHER

No Results Yet

NCT02563522 | TERMINATED | PHASE3

44 participants

Safety and Efficacy Study of Engensis (VM202) in the Treatment of Chronic Non-Healing Foot Ulcers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2017-06-27
Completion:: 2019-09-24

Conditions

Foot Ulcer, Diabetic

Interventions

GENETIC
DRUG

Results Available

NCT02513303 | COMPLETED | PHASE3

269 participants

Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2015-11-30
Completion:: 2021-06-30

Conditions

Complication of Renal Dialysis
End Stage Renal Disease
End Stage Kidney Disease
ESRD
Chronic Kidney Failure
Complication of Hemodialysis
Vascular Access Complication
Arteriovenous Fistula

Interventions

DRUG
PROCEDURE
DEVICE

Results Available

NCT02500849 | ACTIVE_NOT_RECRUITING | PHASE1

12 participants

Safety Study of Zinc Finger Nuclease CCR5-modified Hematopoietic Stem/Progenitor Cells in HIV-1 Infected Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2016-03-10
Completion:: 2026-08-24

Conditions

HIV

Interventions

GENETIC

No Results Yet

NCT02427464 | COMPLETED | PHASE3

507 participants

Phase 3 Gene Therapy for Painful Diabetic Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2016-04-30
Completion:: 2019-04-30

Conditions

Painful Diabetic Neuropathy
Diabetic Neuropathy, Painful

Interventions

BIOLOGICAL
OTHER

Results Available

NCT02000089 | RECRUITING | PHASE3

9000 participants

The Cancer of the Pancreas Screening-5 CAPS5)Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2014-01-06
Completion:: 2028-12-31

Conditions

Pancreas Cancer
Peutz-Jeghers Syndrome (PJS)
Gene Mutation
Germline Mutation Carrier
Lynch Syndrome

Interventions

DRUG
DIAGNOSTIC_TEST
OTHER

No Results Yet

NCT01908777 | COMPLETED | PHASE2

47 participants

A Phase 2 Multicenter Study of High Dose Chemotherapy With Autologous Stem Cell Transplant Followed by Maintenance Therapy With Romidepsin for the Treatment of T Cell Non-Hodgkin Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2013-07-16
Completion:: 2025-10-03

Conditions

T Cell Non-Hodgkin Lymphoma

Interventions

OTHER

No Results Yet

NCT01382706 | TERMINATED | PHASE2

15 participants

Docetaxel and Lapatinib in Metastatic Transitional Cell Carcinoma in Bladder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2011-06-13
Completion:: 2013-07-15

Conditions

Recurrent Bladder Cancer
Stage III Bladder Cancer
Stage IV Bladder Cancer
Transitional Cell Carcinoma of the Bladder

Interventions

DRUG
OTHER
GENETIC

Results Available

NCT01312857 | COMPLETED | PHASE2

75 participants

Study of Hepatic Arterial Infusion With Intravenous Irinotecan, 5FU and Leucovorin With or Without Panitumumab, in Patients With Wild Type RAS Who Have Resected Hepatic Metastases From Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2011-03-07
Completion:: 2024-07-15

Conditions

Metastatic Colorectal Cancer

Interventions

DRUG

Results Available

NCT01285843 | COMPLETED | NA

40 participants

Periprosthetic Bone Mineral Density After Total Hip Arthroplasty Performed Through a Minimally Invasive Anterior Approach (AMIS) With Either an AMIStem or a Quadra Femoral Component

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2010-09-30
Completion:: 2012-09-30

Conditions

Osteoarthritis
Arthritis
Avascular Necrosis
Fracture of the Femoral Neck or Head
Congenital Hip Dysplasia

Interventions

PROCEDURE

Results Available

NCT01241136 | WITHDRAWN | NA

0 participants

Open Wide Excision Versus Minimal Surgery for Pilonidal Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2010-02-19
Completion:: 2014-11-25

Conditions

Pilonidal Disease

Interventions

PROCEDURE

No Results Yet

NCT00748995 | ACTIVE_NOT_RECRUITING

817 participants

Neuropsychological and Mental Outcomes of Operation Iraqi Freedom (OIF): A Longitudinal Cohort Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-09
Start Date:: 2010-08-31
Completion:: 2014-07-10

Conditions

Stress Disorders, Post-Traumatic

No Results Yet

NCT00673010 | COMPLETED | PHASE1

20 participants

Lesion Dosimetry With 124-Iodine in Metastatic Thyroid Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-09
Start Date:: 2005-03-07
Completion:: 2025-10-02

Conditions

Thyroid Cancer

Interventions

RADIATION

No Results Yet

NCT07213453 | COMPLETED | NA

5 participants

Accuracy of Temporary Laminate Restorations With Digital Workflows

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2024-06-05
Completion:: 2025-09-05

Conditions

Esthetics, Dental

Interventions

DEVICE

No Results Yet

NCT07213427 | NOT_YET_RECRUITING

363 participants

Outcomes of Image-guided High-dose-rate Uterovaginal Brachytherapy With Single Implantation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-08
Start Date:: 2025-12-31
Completion:: 2026-06-30

Conditions

LOCALLY ADVANCED CERVICAL CANCERS

Interventions

OTHER

No Results Yet

NCT07213414 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

72 participants

Metagenomic & Metabolomic Study: Bifidobacterium Probiotic Effects on Gut Microbiota & SCFA in Preterm NICU Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2024-09-02
Completion:: 2025-06-30

Conditions

Prematurity
Low Birth Weight Neonates

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07213401 | NOT_YET_RECRUITING | NA

5000 participants

Non-invasive Monitoring of Newborns in the First Hours of Life for the Prevention of SUPC (Sudden Unexpected Postnatal Collapse): Interventional Study With Medical Device

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2025-11-01
Completion:: 2027-06-30

Conditions

Sudden Unexpected Postnatal Collapse -SUPC

Interventions

DEVICE

No Results Yet

NCT07213362 | NOT_YET_RECRUITING | NA

234 participants

Study on the Effect of Online Cognitive Training Doses on Cognitive Function in Individuals With Mild Cognitive Decline

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2025-10-08
Completion:: 2026-06-30

Conditions

Mild Cognitive Disorder

Interventions

DEVICE

No Results Yet

NCT07213336 | COMPLETED | NA

44 participants

A New Treatment for Primary Dysmenorrhea

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2022-12-01
Completion:: 2023-02-01

Conditions

Primary Dysmenorrhea (PD)

Interventions

OTHER

No Results Yet

NCT07213206 | NOT_YET_RECRUITING | PHASE3

1500 participants

CDK4/6 Inhibitor Intensification and Chemotherapy De-Escalation for Early-stage Luminal-HER2 Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2025-10-07
Completion:: 2032-09-01

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT07213193 | RECRUITING | NA

395 participants

No-Stoma Policy in Advanced Ovarian Cancer Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2025-05-01
Completion:: 2028-06-01

Conditions

Ovary Cancer

Interventions

PROCEDURE

No Results Yet

NCT07213180 | COMPLETED

140 participants

Study of the Return to Driving in People Who Have Suffered a Cerebrovascular Accident (CVA)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-08
Start Date:: 2022-11-25
Completion:: 2023-03-25

Conditions

Post-stroke

No Results Yet

NCT07213141 | ACTIVE_NOT_RECRUITING

161 participants

Incidence of Graves' Disease After COVID-19 Vaccination

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-08
Start Date:: 2022-11-08
Completion:: 2025-12-31

Conditions

Graves Disease

Interventions

OTHER

No Results Yet

NCT07213115 | COMPLETED

8582 participants

Epidemiology and Treatment of Gastric Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-08
Start Date:: 2000-01-01
Completion:: 2020-12-31

Conditions

Gastric (Stomach) Cancer
Sex Difference

Interventions

PROCEDURE

No Results Yet

NCT07213102 | NOT_YET_RECRUITING | NA

700 participants

Transform + Family Academy Randomized Controlled Trial in the Philippines

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2025-11-01
Completion:: 2027-05-30

Conditions

Child Development
Child Nutrition, Child Neurobehavioral Development
Household and Family
Financial Wellbeing
Academic Attainment

Interventions

OTHER

No Results Yet

NCT07213089 | COMPLETED | PHASE2/PHASE3

290 participants

Immunogenicity of a Combined Diphtheria-Tetanus-recombinant Acellular Pertussis (DTaP) Vaccine in Healthy Toddlers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2020-07-13
Completion:: 2022-04-04

Conditions

Pertussis Whooping Cough

Interventions

BIOLOGICAL

No Results Yet