Clinical Trials Updated in 2025

NCT06527690 | WITHDRAWN | PHASE2

0 participants

Race Impact on Efficacy of Niraparib Plus Abiraterone Acetate and Prednisone in Patients With Homologous Repair Deficient Castration-resistant Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-04-30
Completion:: 2027-09-30

Conditions

Prostate Cancer
Castrate Resistant Prostate Cancer
Homologous Recombination Deficiency

Interventions

DRUG

No Results Yet

NCT06520202 | TERMINATED | PHASE1/PHASE2

8 participants

RHPRG4 FOR THE TREATMENT OF SJÖGREN'S RELATED DRY EYE DISEASE

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-11-05
Completion:: 2024-11-11

Conditions

Sjogren's Syndrome With Dry Eye

Interventions

DRUG

No Results Yet

NCT06511544 | RECRUITING | NA

20 participants

rTMS to Target Neural Connectivity and Rumination in Treatment-Resistant Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-01-02
Completion:: 2026-06-30

Conditions

Depression, Treatment Resistant

Interventions

DEVICE

No Results Yet

NCT06481982 | WITHDRAWN

0 participants

Value of Advanced MRI Techniques in the Assessment of Endometriosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2026-03-01
Completion:: 2029-08-01

Conditions

Endometriosis

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06481774 | RECRUITING | NA

375 participants

Promoting Access, Resources and Treatment Through Novel and Equitable Solutions for Cancer Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-07-30
Completion:: 2027-06-30

Conditions

Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06467799 | RECRUITING | PHASE2

39 participants

Neoadjuvant HAIC and PD-1 Plus Adjuvant PD-1 for High-risk Recurrent HCC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-09-01
Completion:: 2027-09-01

Conditions

Hepatocellular Carcinoma
Beyond Milan Criteria

Interventions

DRUG

No Results Yet

NCT06465888 | COMPLETED | NA

106 participants

Influence of Eggs on Cognitive Performance

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2017-08-22
Completion:: 2020-03-19

Conditions

Cognitive Function

Interventions

OTHER

No Results Yet

NCT06462092 | RECRUITING | PHASE1/PHASE2

34 participants

Sacituzumab Govitecan and Intrathecal Chemotherapy for Treating Leptomeningeal Metastases From Her2-negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2026-01-01
Completion:: 2027-01-15

Conditions

Leptomeningeal Metastases

Interventions

DRUG

No Results Yet

NCT06447415 | COMPLETED | PHASE1

64 participants

Safety, Tolerability, and Preliminary Efficacy of HRS-7450 Injection in the Treatment of Acute Ischemic Stroke: a Multi-center, Randomized, Double-blind, Double-dummy, Placebo-controlled Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-08-06
Completion:: 2025-03-18

Conditions

Acute Ischemic Stroke

Interventions

DRUG

No Results Yet

NCT06441786 | RECRUITING | NA

36 participants

A Metacognitive Group Therapy of Depression and Anxiety in Youth With Autism

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-08-12
Completion:: 2026-08-29

Conditions

Anxiety Depression

Interventions

BEHAVIORAL

No Results Yet

NCT06426953 | RECRUITING

180 participants

Predictive Effect of TGF-β and INS-PI3K-AKT Related Proteins for POD in Diabetes Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-05-20
Completion:: 2025-12-30

Conditions

Diabetes
Postoperative Delirium

Interventions

OTHER

No Results Yet

NCT06393439 | RECRUITING | NA

48 participants

Virtual Reality in Functional Movement Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-05-01
Completion:: 2025-12-31

Conditions

Functional Movement Disorder

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06389357 | COMPLETED | NA

20 participants

Retun-to-school Adaptation Program for Children With Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2023-05-30
Completion:: 2024-12-06

Conditions

Childhood Cancer
ALL, Childhood
AML, Childhood
Lymphoma
Solid Tumor, Childhood

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06387082 | RECRUITING | PHASE1

132 participants

A Clinical Study of HMPL-506 in Patients With Hematological Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-05-27
Completion:: 2027-10-08

Conditions

Hematological Malignancies

Interventions

DRUG

No Results Yet

NCT06351579 | COMPLETED

30 participants

Data Collection Post Radical Prostatectomy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2023-03-30
Completion:: 2025-07-30

Conditions

Stress Urinary Incontinence
Radical Prostatectomy
BPH

Interventions

OTHER

No Results Yet

NCT06350903 | COMPLETED | NA

16 participants

Suppression With Empagliflozin as an Alternative To High-Fat Low-Carbohydrate Diet for Myocardial F-fluorodeoxyglucose Positron Emission Tomography (FDG-PET) Imaging

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-06-01
Completion:: 2024-11-01

Conditions

Myocardial Suppression

Interventions

OTHER
COMBINATION_PRODUCT

No Results Yet

NCT06349538 | ENROLLING_BY_INVITATION

100 participants

Identifying Markers of Disease Subtypes and Disease Progression in the Syndrome of Essential Tremor

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-04-04
Completion:: 2026-04-30

Conditions

Essential Tremor

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06349317 | RECRUITING | PHASE2

33 participants

Neoadjuvant IMRT Combined With Camrelizumab and Apatinib for Resectable HCC With PVTT

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-04-22
Completion:: 2026-05-31

Conditions

Hepatocellular Carcinoma

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06338917 | ACTIVE_NOT_RECRUITING | NA

100 participants

Moderate-to-Vigorous Intensity Physical Activity and Severe Mental Illness

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-06-01
Completion:: 2025-01-31

Conditions

Mental Health Issue

Interventions

BEHAVIORAL

No Results Yet

NCT06336382 | RECRUITING

16 participants

Tau Biomarkers in Late-onset Psychosis (LOP)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-02-16
Completion:: 2026-12-31

Conditions

Late Onset Schizophrenia
Delusional Disorder (Late Onset)

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06319872 | RECRUITING | PHASE1

15 participants

The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-05-19
Completion:: 2029-05-19

Conditions

Alcohol Use Disorder
Retinal Dystrophies
Age-Related Macular Degeneration
Retinitis Pigmentosa
Stargardt Disease

Interventions

DRUG

No Results Yet

NCT06305611 | RECRUITING

103 participants

European and North Indian Cohort of KaWasaki dIsease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2021-07-13
Completion:: 2026-07-15

Conditions

Kawasaki Disease

No Results Yet

NCT06304441 | RECRUITING | NA

100 participants

Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-04-18
Completion:: 2026-06-20

Conditions

Leptomeningeal Metastasis

Interventions

DRUG

No Results Yet

NCT06300086 | COMPLETED | NA

28388 participants

Nationwide Utilization of Danish Government Electronic Letter System for Increasing Guideline-directed Medical Therapy in Chronic Kidney Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-08-19
Completion:: 2025-02-19

Conditions

Chronic Kidney Diseases
Behavior and Behavior Mechanisms

Interventions

BEHAVIORAL

No Results Yet

NCT06270953 | COMPLETED

54 participants

Non-invasive Monitoring: Impact on Patient Management and Outcomes

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-01-19
Completion:: 2024-04-30

Conditions

No Specific Medical Conditions or Disease States

Interventions

DEVICE

No Results Yet

NCT06259851 | ACTIVE_NOT_RECRUITING | NA

60 participants

rTMS-enhanced Psychotherapy for Borderline Personality Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2023-08-20
Completion:: 2026-12-31

Conditions

Borderline Personality Disorder

Interventions

BEHAVIORAL
DEVICE

No Results Yet

NCT06239064 | ACTIVE_NOT_RECRUITING

1000 participants

Early Genetic Identification of Obesity

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-01-24
Completion:: 2026-03-01

Conditions

Obesity, Childhood
Hyperphagia
Retinopathy
Syndactyly
Polydactyly
Cognitive Impairment
Bardet-Biedl Syndrome
POMC Deficiency

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06230328 | COMPLETED

300 participants

Brazilian Reality of Hepatocellular Carcinoma

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-04-15
Completion:: 2024-11-14

Conditions

Hepatocellular Carcinoma
Hepatocellular Carcinoma by BCLC Stage
Hepatocellular Carcinoma Stage I
Hepatocellular Carcinoma Stage II
Hepatocellular Carcinoma Stage III

No Results Yet

NCT06227494 | ACTIVE_NOT_RECRUITING | NA

63 participants

Dietary Fiber: Is it the Missing Link in Achieving Long Term Behavior Change?

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2023-07-10
Completion:: 2026-01-31

Conditions

Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT06197724 | RECRUITING

14090 participants

MCG for Identification of Myocardial Ischemia in Suspected NSTE-ACS Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-01-02
Completion:: 2025-12-31

Conditions

Non ST Segment Elevation Acute Coronary Syndrome

Interventions

DEVICE

No Results Yet

NCT06188910 | COMPLETED | NA

40 participants

Neurofeedback and Nomophobia in Young Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-04-01
Completion:: 2024-12-31

Conditions

Anxiety
Biofeedback

Interventions

OTHER

No Results Yet

NCT06136156 | COMPLETED

237 participants

Video Vitals and Biomarkers

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2023-10-31
Completion:: 2025-09-04

Conditions

Cardiometabolic Diseases

No Results Yet

NCT06121492 | ENROLLING_BY_INVITATION | PHASE3

86 participants

Oral Branched-chain Amino Acid Supplementation for Cirrhotic Patients With Sarcopenia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2023-11-15
Completion:: 2026-06-30

Conditions

Sarcopenia
Cirrhosis of the Liver

Interventions

DRUG

No Results Yet

NCT06121479 | ENROLLING_BY_INVITATION | PHASE3

30 participants

Oral Branched-chain Amino Acid Supplementation for Decompensated Cirrhotic Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2023-11-13
Completion:: 2025-09-23

Conditions

Decompensated Cirrhosis and Ascites

Interventions

DRUG

No Results Yet

NCT06098651 | COMPLETED | PHASE1

26 participants

A Study of DCR-STAT3 in Adults With Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2023-08-14
Completion:: 2025-09-17

Conditions

Solid Tumor, Adult
Refractory Tumor

Interventions

DRUG

No Results Yet

NCT06097143 | COMPLETED | NA

42 participants

Clinical Performance of Flowable Giomer Versus Nanofilled Composite in Conservative Occlusal Cavities

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2023-12-15
Completion:: 2025-06-19

Conditions

Occlusal Caries

Interventions

OTHER

No Results Yet

NCT06088472 | RECRUITING | PHASE1

12 participants

TIL Injection for the Treatment of Metastatic or Recurrent Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2021-04-21
Completion:: 2027-12-31

Conditions

Solid Tumors, Adult

Interventions

BIOLOGICAL

No Results Yet

NCT06072170 | COMPLETED | PHASE1

40 participants

Single Ascending Doses of Kratom in Healthy Nondependent Adults With Opioid Experience

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2023-08-16
Completion:: 2024-01-23

Conditions

Safety
Pharmacokinetics
Pharmacodynamics

Interventions

DRUG

Results Available

NCT06056427 | NO_LONGER_AVAILABLE

Intermediate Size Expanded Access Protocol Using Autologous HB-adMSCs for the Treatment of Parkinson's Disease

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-09-29

Conditions

Parkinson Disease

Interventions

BIOLOGICAL

No Results Yet

NCT06056310 | TERMINATED | PHASE1

18 participants

Phase 1b Safety Study of Xevinapant, Weekly Cisplatin, and RT in Participants With Unresected LA SCCHN (HyperlynX)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-01-18
Completion:: 2024-08-20

Conditions

Head and Neck Cancer

Interventions

DRUG
RADIATION

Results Available