Clinical Trials

NCT04823130 | COMPLETED | PHASE4

54 participants

Dupilumab Effect on Pruritus Neuro-mechanisms in Patients With Atopic Dermatitis

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2021-04-22

Completion:

2022-06-30

Conditions

• Dermatitis Atopic

Interventions

• DRUG

Results Available

NCT04802447 | NO_LONGER_AVAILABLE

SurVaxM Expanded Access Protocol

Study Type:

EXPANDED_ACCESS

Last Updated:

2025-09-16

Conditions

• Glioblastoma

Interventions

• DRUG

No Results Yet

NCT04801290 | RECRUITING

250 participants

TIPS in Patients With Decompensated Liver Cirrhosis

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2019-08-29

Completion:

2027-12-31

Conditions

• Decompensated Liver Cirrhosis

Interventions

• PROCEDURE

No Results Yet

NCT04795193 | ENROLLING_BY_INVITATION | NA

248 participants

MInithoraCotomy vs Sternotomy for Multivessel Coronary Artery Bypass Grafting: A Partially Randomized Patient Preference Trial Assessing Quality of Life and Patency Outcomes

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2021-04-15

Completion:

2025-12-31

Conditions

• Coronary Artery Bypass, Off-Pump
• Minimally Invasive Cardiac Surgery

Interventions

• PROCEDURE

No Results Yet

NCT04794322 | RECRUITING

250 participants

Developing a Test of Uterine Lavage for the Detection of Ovarian Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2020-04-13

Completion:

2027-08-31

Conditions

• Ovarian Neoplasms
• Ovarian Epithelial Carcinoma
• Fallopian Tube Neoplasms
• High Grade Ovarian Serous Adenocarcinoma
• Stage I Ovarian Cancer
• Stage II Ovarian Cancer
• Stage III Ovarian Cancer AJCC v8
• Stage IIIA Ovarian Cancer AJCC v8
• Stage IIIA1 Ovarian Cancer AJCC v8
• Stage IIIA2 Ovarian Cancer AJCC v8
• Stage IIIB Ovarian Cancer AJCC v8
• Stage IIIC Ovarian Cancer AJCC v8
• Stage IV Ovarian Cancer AJCC v8
• Stage IVA Ovarian Cancer AJCC v8
• Stage IVB Ovarian Cancer AJCC v8

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04765722 | COMPLETED | PHASE4

46 participants

Mepolizumab for the Treatment of Chronic Cough With Eosinophilic Airways Diseases

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2021-12-14

Completion:

2024-11-12

Conditions

• Chronic Cough
• Eosinophilic Bronchitis
• Asthma

Interventions

• DRUG

Results Available

NCT04759274 | RECRUITING | NA

30 participants

Diuretic Tuner Clinical Decision Support

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2023-11-20

Completion:

2026-08-31

Conditions

• Edema
• Hypervolemia
• Chronic Kidney Diseases
• Nephrotic Syndrome

Interventions

• DEVICE

No Results Yet

NCT04728516 | RECRUITING | PHASE4

2600 participants

The Effect of Dual Eradication Therapy vs PPI on Gastrointestinal Bleeding in ACS Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2023-04-12

Completion:

2026-06-30

Conditions

• Acute Coronary Syndrome
• Helicobacter Pylori Infection

Interventions

• DRUG

No Results Yet

NCT04726839 | COMPLETED

3880 participants

Biomarkers algOrithm for strOke diagnoSis and Treatment Resistance Prediction

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2021-03-12

Completion:

2025-07-10

Conditions

• Stroke, Ischemic
• Large Vessel Occlusion

Interventions

• OTHER

No Results Yet

NCT04697056 | TERMINATED | PHASE2

5 participants

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Participants With Ichthyosis

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2021-01-25

Completion:

2021-11-19

Conditions

• Ichthyosis

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT04655508 | TERMINATED | PHASE3

35 participants

Efficacy of Fluticasone Propionate Associated With Salmeterol Using Inhalation Chamber Versus Placebo to Improve the Respiratory Function in Children Over Six Years of Age Who Underwent Allogeneic Hematopoietic Stem Cell Transplantation With a Decline of FEV1 ≥10% From Pre Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2021-05-21

Completion:

2023-09-27

Conditions

• Stem Cell Transplant Complications
• Respiratory Disease
• Bronchiolitis Obliterans

Interventions

• DRUG

No Results Yet

NCT04609839 | WITHDRAWN

0 participants

FOLLOW-UP OF PATIENTS WITH COVID-19.

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2020-09-15

Completion:

2023-10-17

Conditions

• Patient Admitted to Intensive Care Unit for COVID-19

Interventions

• OTHER

No Results Yet

NCT04586972 | COMPLETED

977 participants

Safety and Efficacy of Apixaban in Very Old Geriatric Subjects (> 80 Years) With Atrial FIbrillation in a Prospective reAl World Study;

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2020-09-23

Completion:

2023-12-21

Conditions

• Nonvalvular Atrial Fibrillation

No Results Yet

NCT04555655 | COMPLETED | EARLY_PHASE1

276 participants

The Effects of Chicken Extract and a Peptide Supplement for the Prevention of Cognitive Decline in Non-demented Elderly Adults

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2020-12-11

Completion:

2024-11-15

Conditions

• Cognitive Decline
• Mild Cognitive Impairment
• Aging

Interventions

• DIETARY_SUPPLEMENT
• OTHER

No Results Yet

NCT04550832 | COMPLETED | PHASE2

76 participants

PanACEA DElpazolid Dose-finding and COmbination DEvelopment (DECODE)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2021-10-28

Completion:

2023-01-04

Conditions

• Infections and Infestations
• Pulmonary Tuberculosis

Interventions

• DRUG

Results Available

NCT04537416 | ACTIVE_NOT_RECRUITING

1000 participants

Fertility, Hypercoagulability, and Inflammation (FREYA) Registry

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2018-04-01

Completion:

2026-06-30

Conditions

• Thrombophilia

Interventions

• OTHER

No Results Yet

NCT04535128 | COMPLETED

11000 participants

COVID-19 Registry to Assess Frequency, Risk Factors, Management, and Outcomes of Arterial and Venous Thromboembolic Complications

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2020-03-24

Completion:

2023-12-30

Conditions

• Covid19
• Thrombosis Embolism
• DVT
• Pulmonary Embolism
• Myocardial Infarction
• Stroke

Interventions

• OTHER

No Results Yet

NCT04520516 | COMPLETED | NA

148 participants

Auricular Vagus Nerve Stimulation in Painful and Inflammatory Erosive Hand Osteoarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2021-04-08

Completion:

2022-06-30

Conditions

• Osteoarthritis
• Musculoskeletal Pain
• Erosive Osteoarthritis

Interventions

• DEVICE

No Results Yet

NCT04511988 | ACTIVE_NOT_RECRUITING | NA

20 participants

Using Liquid Biopsy in Newly Diagnosed Patients With High Grade Adenocarcinoma of Ovarian Origin, Fallopian Tubes or Primary Peritoneal

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2021-07-17

Completion:

2026-07-31

Conditions

• Ovarian Cancer

Interventions

• OTHER

No Results Yet

NCT04478773 | TERMINATED | NA

18 participants

Adverse Events of MRI With Abandoned Leads

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2020-12-02

Completion:

2023-06-30

Conditions

• Pacemaker Electrode Lead Fracture
• ICD

Interventions

• PROCEDURE

No Results Yet

NCT04431895 | COMPLETED | EARLY_PHASE1

19 participants

Safety And Efficacy Of Tofacitinib In Patients With Refractory Myasthenia Gravis: A Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2020-06-11

Completion:

2024-03-21

Conditions

• Myasthenia Gravis, Generalized

Interventions

• DRUG

No Results Yet

NCT04356677 | WITHDRAWN | PHASE1

0 participants

Study to Evaluate the Safety and Efficacy of VIRAZOLE® in Hospitalized Adult Participants With Respiratory Distress Due to COVID-19_#2

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2021-05-31

Completion:

2021-08-31

Conditions

• COVID19

Interventions

• DRUG

No Results Yet

NCT04314375 | RECRUITING | PHASE4

70 participants

Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets in Pediatric Subjects Aged 5 to 17 Years With Active, Mild to Moderate Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2023-09-29

Completion:

2026-12-31

Conditions

• Ulcerative Colitis

Interventions

• DRUG

No Results Yet

NCT04313725 | TERMINATED | NA

28 participants

Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2020-02-24

Completion:

2023-06-21

Conditions

• Stevens-Johnson Syndrome
• Graft Versus Host Disease in Eye
• Sjogren's Syndrome
• Dry Eye

Interventions

• DEVICE
• OTHER

No Results Yet

NCT04261959 | COMPLETED

41 participants

myoActivation® for Chronic Pain in a Marginalized Population

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2020-02-18

Completion:

2022-08-02

Conditions

• Pain, Chronic
• Widespread Chronic Pain

Interventions

• OTHER

No Results Yet

NCT04250298 | COMPLETED | NA

50 participants

Sucrosom5al Iron Supplementation in Blood Donors

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2019-11-13

Completion:

2020-09-28

Conditions

• Iron-deficiency

Interventions

• DIETARY_SUPPLEMENT

Results Available

NCT04249622 | TERMINATED | PHASE2

20 participants

Rifaximin for the Treatment of Gastrointestinal Toxicities Related to Pertuzumab-Based Therapy in Patients With Stage I-III HER2 Positive Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2020-09-18

Completion:

2022-12-27

Conditions

• Anatomic Stage I Breast Cancer AJCC v8
• Anatomic Stage IA Breast Cancer AJCC v8
• Anatomic Stage IB Breast Cancer AJCC v8
• Anatomic Stage II Breast Cancer AJCC v8
• Anatomic Stage IIA Breast Cancer AJCC v8
• Anatomic Stage IIB Breast Cancer AJCC v8
• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IIIA Breast Cancer AJCC v8
• Anatomic Stage IIIB Breast Cancer AJCC v8
• Anatomic Stage IIIC Breast Cancer AJCC v8
• HER2 Positive Breast Carcinoma
• Prognostic Stage I Breast Cancer AJCC v8
• Prognostic Stage IA Breast Cancer AJCC v8
• Prognostic Stage IB Breast Cancer AJCC v8
• Prognostic Stage II Breast Cancer AJCC v8
• Prognostic Stage IIA Breast Cancer AJCC v8
• Prognostic Stage IIB Breast Cancer AJCC v8
• Prognostic Stage III Breast Cancer AJCC v8
• Prognostic Stage IIIA Breast Cancer AJCC v8
• Prognostic Stage IIIB Breast Cancer AJCC v8
• Prognostic Stage IIIC Breast Cancer AJCC v8

Interventions

• OTHER
• DRUG

Results Available

NCT04247880 | COMPLETED | NA

96 participants

The Use of Mentoring to Promote Well-being for Female SMART Members

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2021-03-01

Completion:

2024-07-01

Conditions

• Harassment, Non-Sexual
• Harassment, Sexual
• Bullying, Workplace
• Mental Stress
• Work-Related Condition
• Work-related Injury
• Work Related Stress

Interventions

• BEHAVIORAL

Results Available

NCT04242147 | TERMINATED | PHASE1

45 participants

A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KD033 (SAR445710) in Subjects With Metastatic or Locally Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2023-03-06

Completion:

2023-12-01

Conditions

• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT04240886 | TERMINATED | PHASE2

21 participants

Open-label Study of APX001 for Treatment of Patients With Invasive Mold Infections Caused by Aspergillus or Rare Molds

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2020-01-04

Completion:

2022-03-29

Conditions

• Invasive Fungal Infections

Interventions

• DRUG

Results Available

NCT04216784 | TERMINATED | PHASE4

21 participants

Compare the Diuretic Effect With Furosemide vs Furosemide and Albumin Combined in Cirrhotic Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2019-12-19

Completion:

2023-12-30

Conditions

• Cirrhosis, Liver
• Volume Overload
• Fluid Overload

Interventions

• DRUG

Results Available

NCT04210349 | COMPLETED | PHASE3

7106 participants

Study of Shenzhen Quadrivalent Inactivated Influenza Vaccine Versus the Shenzhen Trivalent Inactivated Influenza Vaccine in Chinese Subjects From 6 Months of Age

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2020-01-09

Completion:

2020-12-01

Conditions

• Influenza

Interventions

• BIOLOGICAL

No Results Yet

NCT04173377 | COMPLETED

310 participants

Elbow Outcomes Clinical Study (WELBOW)

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2020-06-08

Completion:

2024-09-17

Conditions

• Orthopedic Disorder

No Results Yet

NCT04162353 | RECRUITING | PHASE1

12 participants

BCMA-CD19 cCAR in Multiple Myeloma and Plasmacytoid Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2019-07-01

Completion:

2026-07-31

Conditions

• Multiple Myeloma in Relapse
• Refractory Multiple Myeloma
• Plasmacytoid; Lymphoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04159727 | COMPLETED | NA

15 participants

Gut Microbiota Dysbiosis and Translocation During IBD and Parkinson

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2019-03-28

Completion:

2020-02-13

Conditions

• Inflammatory Bowel Diseases
• Parkinson Disease

Interventions

• OTHER

No Results Yet

NCT04149574 | TERMINATED | PHASE3

13 participants

A Study Comparing the Efficacy and Safety of Nivolumab in Combination With Bacillus Calmette-Guerin (BCG) Versus BCG Alone in Participants With High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2020-01-15

Completion:

2023-10-31

Conditions

• Urinary Bladder Neoplasms

Interventions

• DRUG
• OTHER
• BIOLOGICAL

Results Available

NCT04148287 | COMPLETED | PHASE2

9 participants

An Open-label Study of APX001 for Treatment of Patients With Candidemia/Invasive Candidiasis Caused by Candida Auris

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2019-12-13

Completion:

2020-11-30

Conditions

• Candidemia
• Invasive Candidiases
• Candida Infection

Interventions

• DRUG

Results Available

NCT04137237 | RECRUITING

417 participants

Hand & Wrist Pyrocarbon Implants Outcomes Clinical Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2019-11-14

Completion:

2029-01-31

Conditions

• Orthopedics

No Results Yet

NCT04107038 | COMPLETED | NA

170 participants

Monitored Anesthesia Care vs. General Anesthesia for Transcatheter Aortic Valve Replacement

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2019-11-22

Completion:

2025-07-15

Conditions

• Transcatheter Aortic Valve Replacement

Interventions

• PROCEDURE

No Results Yet

NCT04088721 | COMPLETED | PHASE1/PHASE2

48 participants

Tolerability and Potential Efficacy of AD17002 in Subjects With Allergic Rhinitis

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2019-03-26

Completion:

2020-07-30

Conditions

• Allergic Rhinitis

Interventions

• BIOLOGICAL
• OTHER

No Results Yet