Clinical Trials Updated in 2025

NCT07152366 | RECRUITING | PHASE4

96 participants

Efficacy and Safety of Sequential Hormone Therapy and Tetuzumab Therapy in Patients With Moderate to Severe TAO in the Active Stage After Glucocorticoid Treatment.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-04-15
Completion:: 2027-05-31

Conditions

Thyroid Associated Ophthalmopathies

Interventions

DRUG

No Results Yet

NCT07152340 | RECRUITING | PHASE4

64 participants

The Safety and Efficacy of Sequential Hormone Therapy and IBI311 Therapy in Patients With Active Moderate to Severe TAO in the Initial Treatment.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-04-10
Completion:: 2027-04-30

Conditions

Thyroid Associated Ophthalmopathies

Interventions

DRUG

No Results Yet

NCT07152288 | RECRUITING | PHASE1

24 participants

Investigation of Pharmacokinetics,Safety,and Pharmacodynamics of HSK39297 in Subjects With Hepatic Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-05-29
Completion:: 2025-09-30

Conditions

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Interventions

DRUG

No Results Yet

NCT07152145 | NOT_YET_RECRUITING | NA

60 participants

Pilot Study of tSCS for Improving Upper Limb Function in People With Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-10-31
Completion:: 2026-12-31

Conditions

Multiple Sclerosis

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT07152106 | RECRUITING

275 participants

Amniotic Fluid & the Preterm Gut

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-03
Start Date:: 2024-10-14
Completion:: 2026-10-14

Conditions

Chorioamnionitis
Chorioamnionitis Affecting Fetus or Newborn
Necrotizing Enterocolitis of Newborn
Neonatal Sepsis, Early-Onset
Neonatal Sepsis, Late-Onset
Fetal Growth Restriction (FGR)
Preterm Birth Complication
Prematurity Complications

No Results Yet

NCT07152067 | NOT_YET_RECRUITING | PHASE2

146 participants

Stereotactic Focal Radiotherapy as an Alternative Treatment to Active Surveillance for Low and Intermediate Risk Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-09-30
Completion:: 2030-09-01

Conditions

Macroscopic Tumor Visualized at MRI
Tumor Size Allowing Partial Prostate Treatment Volume
CAPRA SCORE ≤5

Interventions

RADIATION

No Results Yet

NCT07152054 | NOT_YET_RECRUITING | NA

70 participants

The Effect of Virtual Forest Bathing on Bariatric Surgery Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-08-25
Completion:: 2025-12-25

Conditions

Bariatric Surgery
Virtual Reality
Anxiety

Interventions

DEVICE

No Results Yet

NCT07152041 | RECRUITING | PHASE3

150 participants

Newly-diagnosed Pediatric Ph-positive B-ALL Protocol

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-03-28
Completion:: 2029-12-31

Conditions

Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+)
Childhood Leukemia, Acute Lymphoblastic

Interventions

DRUG

No Results Yet

NCT07151989 | ENROLLING_BY_INVITATION

3500 participants

Influence of Original Native Mitral Valve Lesion (Stenosis or Steno-insufficiency vs. Insufficiency) on Post-implant Structural Bioprosthetic Degeneration After Mitral Valve Replacement

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-03
Start Date:: 2024-01-01
Completion:: 2025-11-01

Conditions

Degeneration Mitral Bioprosthesis

Interventions

PROCEDURE

No Results Yet

NCT07151950 | ACTIVE_NOT_RECRUITING

50 participants

Obi Medical Robot: Evaluating Effectiveness Related to Usability

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-05-10
Completion:: 2025-08-12

Conditions

Upper Extremity Impairments
Cerebral Palsy (CP)
ALS - Amyotrophic Lateral Sclerosis
Rett Syndrome

Interventions

DEVICE

No Results Yet

NCT07151911 | RECRUITING

100 participants

Real wOrld studY in the Adjuvant Setting for High Risk earLy Breast Cancer Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-03
Start Date:: 2024-08-26
Completion:: 2026-09-30

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT07151898 | RECRUITING

50 participants

PET/CT for Trop2 ADC Response Evaluation NSCLC

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-05-01
Completion:: 2027-05-01

Conditions

NSCLC
Trop2
PET/CT

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07151872 | NOT_YET_RECRUITING | PHASE2

120 participants

Combination of QLS31905 and Chemotherapy ± QL2107 in Patients With CLDN18.2-positive Advanced Biliary Tract Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-09-30
Completion:: 2026-10-31

Conditions

CLDN18.2-positive Advanced Biliary Tract Cancer

Interventions

DRUG

No Results Yet

NCT07151846 | ENROLLING_BY_INVITATION

540 participants

Digital Phenotypes for Predicting Depression

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-02-27
Completion:: 2026-08-31

Conditions

Depression - Major Depressive Disorder
Depression Bipolar
Bipolar Disorder (BD)
Mood Disorders

No Results Yet

NCT07151833 | NOT_YET_RECRUITING | NA

126 participants

GlucoBites Cookies (Gynura Procumbens) for Glycemic Control and Prevention of Diabetic Foot Ulcer Risk in Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-09-20
Completion:: 2025-12-20

Conditions

Type 2 Diabetes Mellitus
Diabetic Neuropathy

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07151820 | COMPLETED

2546 participants

A Real-world Study About the Impact of Adverse Events (AEs) on Treatment Adjustments, Healthcare Resource Use, and Costs Among Chronic Myeloid Leukemia Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-03
Start Date:: 2024-04-08
Completion:: 2024-10-22

Conditions

Leukemia, Chronic Myeloid

No Results Yet

NCT07151807 | ACTIVE_NOT_RECRUITING

100 participants

Serum IGF-1 and IGF-1Ec in Malignancy Assessment

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-04-01
Completion:: 2025-12-31

Conditions

Cancer
Solid Tumor Malignancies
IGF1R
Solid Cancers

No Results Yet

NCT07151794 | ACTIVE_NOT_RECRUITING

150 participants

G8, CARG, Frailty, and Nutritional Markers in Predicting Chemotoxicity

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-01-02
Completion:: 2025-12-31

Conditions

Geriatric Oncology
Oncology
Nutrition
Nutrition Assessment

No Results Yet

NCT07151781 | NOT_YET_RECRUITING | NA

120 participants

Technology Supported Mindfulness for Prenatal Depression and Mental Health-related Quality of Life in a Resource-Limited Environment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-11-01
Completion:: 2025-12-30

Conditions

Prenatal Depression
Mental Health Related Quality of Life
Maternal Postpartum Depression
Paternal Postpartum Depression

Interventions

OTHER

No Results Yet

NCT07151768 | RECRUITING

100 participants

Prospective Validation of the Novel PVD-B65 Risk Score in Patients With Chronic Lung Disease and Pulmonary Hypertension

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-09-01
Completion:: 2028-08-31

Conditions

Chronic Lung Disease
Pulmonary Hypertension

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07151755 | RECRUITING | NA

24 participants

Microneedle Intra-Arterial Injection for Retinal Artery Occlusion

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-09-01
Completion:: 2027-07-31

Conditions

Central Retinal Artery Occlusion

Interventions

PROCEDURE

No Results Yet

NCT07151742 | ENROLLING_BY_INVITATION | NA

40 participants

Effects of Intradialytic Exercise on Muscle Oxygenation and Dialysis Adequacy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-05-25
Completion:: 2025-11-25

Conditions

Chronic Kidney Disease, Stage 5
Sarcopenia

Interventions

OTHER

No Results Yet

NCT07151729 | RECRUITING | NA

50 participants

Use of Anodal tDCS to Enhance Upper Limb Recovery in Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-09-01
Completion:: 2026-09-15

Conditions

Stroke

Interventions

DEVICE

No Results Yet

NCT07151703 | NOT_YET_RECRUITING | PHASE3

60 participants

Topical Versus Injection PRP for Olfactory Dysfunction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-10-01
Completion:: 2027-12-31

Conditions

Olfactory Dysfunction
Anosmia
Hyposmia

Interventions

PROCEDURE
COMBINATION_PRODUCT
DEVICE

No Results Yet

NCT07151677 | RECRUITING | NA

60 participants

Brain Stimulation Effects on Post-Stroke Fatigue and Aphasia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-08-04
Completion:: 2029-09-30

Conditions

Aphasia Following Cerebral Infarction
Stroke Ischemic
Fatigue Symptom

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT07151664 | NOT_YET_RECRUITING

60 participants

Retrospective Analysis of Quality of Life Changes in Patients Undergoing Parathyroidectomy for End-Stage Renal Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-09-05
Completion:: 2025-12-05

Conditions

Secondary Hyperparathyroidism Due to Renal Causes
End Stage Renal Failure

Interventions

OTHER

No Results Yet

NCT07151651 | NOT_YET_RECRUITING | NA

60 participants

A Comparison Between Biportal and Uniportal Endoscopic Lumbar Discectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-09-01
Completion:: 2026-09-01

Conditions

Lumbar Disc Herniation

Interventions

PROCEDURE

No Results Yet

NCT07151625 | NOT_YET_RECRUITING | NA

40 participants

Protein Complementation of Plant-based Diets.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-10-01
Completion:: 2029-09-30

Conditions

Each Participant Will be Studied Over 5 Dietary Periods, Each Over 9d

Interventions

OTHER

No Results Yet

NCT07151560 | NOT_YET_RECRUITING | PHASE2

60 participants

Efficacy and Safety of Two Bladder-preserving Treatment Durations With Disitamab Vedotin Plus Toripalimab Combination in Her2-expressing Muscle-invasive Bladder Cancer: A Phase II, Open-Label, Randomized Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-08-30
Completion:: 2027-08-30

Conditions

Urology

Interventions

DRUG

No Results Yet

NCT07151495 | NOT_YET_RECRUITING

300 participants

Additive Prognostic Value of PALS Compared to Bernard's Staging in Patients Undergoing MV Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-09-15
Completion:: 2025-12-15

Conditions

Mitral Regurgitation

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07151482 | NOT_YET_RECRUITING

43 participants

Impact of Oral Supplementation With Bioactive Collagen Peptides and Other Functional Ingredients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-09-01
Completion:: 2027-09-01

Conditions

Genitourinary Syndrome of Menopause

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07151456 | NOT_YET_RECRUITING | PHASE4

224 participants

Short-term gluCOCOrticoid in Adult STEROID-sensitive Nephrotic Syndrome: The COCO-ASTEROID Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2026-01-31
Completion:: 2029-12-31

Conditions

Idiopathic Nephrotic Syndrome

Interventions

DRUG

No Results Yet

NCT07151430 | NOT_YET_RECRUITING | NA

358 participants

Development and Validation of a Comprehensive Management Service Package for Older Adults With Multimorbidity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-12-01
Completion:: 2026-06-01

Conditions

Multimorbidity
Hypertension
Diabetes Mellitus
Coronary Artery Disease
Dyslipidemia
Stroke
Arthritis
Cognitive Impairment
Depression - Major Depressive Disorder
Chronic Kidney Disease
Chronic Liver Diseases

Interventions

DEVICE

No Results Yet

NCT07151404 | NOT_YET_RECRUITING | NA

130 participants

Efficacy of Acupuncture at Lieque (LU7) for Neck Pain in Cervical Spondylosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-09-01
Completion:: 2026-03-01

Conditions

Cervical Spondylosis
Neck Pain

Interventions

PROCEDURE

No Results Yet

NCT07151352 | ACTIVE_NOT_RECRUITING | NA

37 participants

Footwear and Brain Activity in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-08-01
Completion:: 2025-08-10

Conditions

Foot
Footwear
Children

Interventions

OTHER

No Results Yet

NCT07151339 | RECRUITING

100 participants

Pilot Project Renal and Cardiovascular Tertiary Prevention in Preeclampsia

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-03
Start Date:: 2024-11-01
Completion:: 2029-11-30

Conditions

Preeclampsia
HELLP Syndrome
Eclampsia
Kidney Disease

No Results Yet

NCT07151326 | NOT_YET_RECRUITING | PHASE2

60 participants

Cabozantinib for Progressive HCC Post-first-line Immuno-oncologic Combination Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-09-30
Completion:: 2028-06-30

Conditions

Hepatocellular Carcinoma (HCC)

Interventions

DRUG

No Results Yet

NCT07151287 | NOT_YET_RECRUITING

64 participants

Diagnosis of Intracranial Hypertension Using TCCD, ONSD and ODH by Bedside Ultrasound

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-09-15
Completion:: 2027-07-01

Conditions

Traumatic Brain Injury

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07151222 | RECRUITING

500 participants

Role of Red Blood Cells in Cardiovascular Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-03
Start Date:: 2017-01-01
Completion:: 2030-12-30

Conditions

Diabetes Mellitus

No Results Yet

NCT07151209 | NOT_YET_RECRUITING | PHASE2

20 participants

Immunotherapy Combined With Anti-angiogenic Therapy and Chemotherapy for Potentially Resectable MSI-H, dMMR Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-03
Start Date:: 2025-09-30
Completion:: 2028-12-31

Conditions

Gastric or Gastroesophageal Junction Adenocarcinoma

Interventions

DRUG

No Results Yet