Clinical Trials

NCT04736667 | RECRUITING

1000 participants

Mitral Valve Screening Survey

Study Type:

OBSERVATIONAL

Last Updated:

2025-08-29

Start Date:

2021-08-06

Completion:

2027-02-28

Conditions

• Mitral Valve Disease

No Results Yet

NCT04652973 | ACTIVE_NOT_RECRUITING

118 participants

Evaluation of Atherosclerotic Plaques in Abdominal CT Studies

Study Type:

OBSERVATIONAL

Last Updated:

2025-08-29

Start Date:

2020-11-19

Completion:

2030-08-30

Conditions

• Prostatic Neoplasms

No Results Yet

NCT04651777 | ACTIVE_NOT_RECRUITING | PHASE3

31 participants

Evaluation of Triple Therapy Using Magnetic Resonance Imaging in Asthma

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2022-08-08

Completion:

2023-08-25

Conditions

• Asthma

Interventions

• DRUG

Results Available

NCT04601233 | NOT_YET_RECRUITING | PHASE4

20 participants

Testosterone Treatment for Erectile Dysfunction and Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2026-06-30

Completion:

2026-12-31

Conditions

• Multiple Sclerosis
• Erectile Dysfunction
• Testosterone Deficiency

Interventions

• DRUG

No Results Yet

NCT04577313 | RECRUITING | NA

400 participants

HIV Treatment Adherence Dose Determination Trial

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2020-09-01

Completion:

2026-11-30

Conditions

• HIV Infections

Interventions

• BEHAVIORAL

No Results Yet

NCT04564027 | COMPLETED | PHASE2

54 participants

A Study Investigating DNA-damage Response Agents in Molecularly Altered Advanced Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2020-12-01

Completion:

2025-02-18

Conditions

• Advanced Solid Tumours

Interventions

• DRUG

Results Available

NCT04556175 | TERMINATED | NA

16 participants

Great Beginnings for Healthy Native Smiles: An Early Childhood Caries Prevention Project

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2021-03-29

Completion:

2022-03-01

Conditions

• Early Childhood Caries
• Dental Caries

Interventions

• BEHAVIORAL

Results Available

NCT04482621 | SUSPENDED | PHASE2

33 participants

Decitabine for Coronavirus (COVID-19) Pneumonia- Acute Respiratory Distress Syndrome (ARDS) Treatment: DART Trial

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2020-09-14

Completion:

2026-07-31

Conditions

• COVID-19

Interventions

• DRUG
• OTHER

No Results Yet

NCT04481997 | COMPLETED

1000 participants

Anti-thrombotic and Glucose Lowering Therapy in Diabetic Patients Undergoing PCI

Study Type:

OBSERVATIONAL

Last Updated:

2025-08-29

Start Date:

2021-01-11

Completion:

2023-11-04

Conditions

• Type2 Diabetes Mellitus
• Coronary Heart Disease

Interventions

• OTHER

No Results Yet

NCT04453722 | COMPLETED

49 participants

Prevention of Opioid-Induced Hypoxemia

Study Type:

OBSERVATIONAL

Last Updated:

2025-08-29

Start Date:

2020-06-26

Completion:

2022-04-30

Conditions

• Non-cardiac Surgery

Interventions

• DEVICE

Results Available

NCT04428580 | COMPLETED | NA

151 participants

Implementing FBT for Adolescent AN for Providers in Private Practice

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2020-11-20

Completion:

2024-08-02

Conditions

• Online Training for Therapists

Interventions

• OTHER

Results Available

NCT04423718 | COMPLETED | PHASE3

1011 participants

Study of the Effects of High Dose Aflibercept Injected Into the Eye of Patients With an Age-related Disorder That Causes Loss of Vision Due to Growth of Abnormal Blood Vessels at the Back of the Eye

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2020-08-11

Completion:

2022-07-27

Conditions

• Neovascular Age-Related Macular Degeneration

Interventions

• DRUG

Results Available

NCT04413344 | COMPLETED | PHASE1/PHASE2

8 participants

Repurposing Bromocriptine for Abeta Metabolism in Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2020-06-05

Completion:

2021-11-24

Conditions

• Familial Alzheimer Disease (FAD)
• PSEN1 Mutation

Interventions

• DRUG

No Results Yet

NCT04403802 | COMPLETED | NA

28 participants

Voxx Human Performance Technology Socks for Chemotherapy-Induced Peripheral Neuropathy

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2020-10-16

Completion:

2024-05-22

Conditions

• Neuropathy;Peripheral
• Chemotherapy-induced Peripheral Neuropathy
• Neuropathy

Interventions

• DEVICE

Results Available

NCT04350060 | COMPLETED | NA

10 participants

Improving the Quality of Dementia Care Through Innovative Redesign of the Memory Care Environment

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2020-02-02

Completion:

2024-01-29

Conditions

• Dementia

Interventions

• OTHER

No Results Yet

NCT04332848 | RECRUITING | PHASE4

360 participants

Susceptibility Testing Guided Versus Empirical Therapy for Refractory H. Pylori Infection

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2020-07-28

Completion:

2025-12-31

Conditions

• Helicobacter Pylori Infection

Interventions

• DRUG

No Results Yet

NCT04327609 | COMPLETED | NA

84 participants

SAVE Trial - Use of the Selution Sirolimus Eluting Balloon for Dysfunctional AV accEss Treatment Indications

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2020-04-10

Completion:

2024-02-01

Conditions

• AV Fistula

Interventions

• DEVICE

No Results Yet

NCT04228276 | TERMINATED | NA

30 participants

Treating Stimulant Addiction With Repetitive Transcranial Magnetic Stimulation

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2021-02-05

Completion:

2024-04-30

Conditions

• Stimulant Use Disorder
• Substance-related Disorders

Interventions

• DEVICE

Results Available

NCT04209634 | COMPLETED | PHASE2/PHASE3

10 participants

Open-Label Efficacy and Safety Study of Pozelimab in Patients With CD55-Deficient Protein-Losing Enteropathy (CHAPLE Disease)

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2020-01-27

Completion:

2021-11-09

Conditions

• CD55-deficient Protein-losing Enteropathy
• CHAPLE

Interventions

• DRUG

Results Available

NCT04168866 | RECRUITING | NA

180 participants

Operative Versus Non-Operative Management for Appendicitis With Abscess or Phlegmon

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2020-03-11

Completion:

2028-12-31

Conditions

• Appendicitis

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04134598 | ACTIVE_NOT_RECRUITING | PHASE3

926 participants

ExclUsive endocRine Therapy Or Radiation theraPy for Women Aged ≥70 Years Early Stage Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2021-02-08

Completion:

2030-03-31

Conditions

• Breast Cancer

Interventions

• RADIATION
• DRUG

No Results Yet

NCT04112992 | RECRUITING

600 participants

An International, Multicenter, Prospective Registry on Post-traumatic Long Bones Defects

Study Type:

OBSERVATIONAL

Last Updated:

2025-08-29

Start Date:

2024-07-03

Completion:

2028-05-31

Conditions

• Limb Fracture
• Bone Loss

Interventions

• PROCEDURE

No Results Yet

NCT04081558 | COMPLETED | NA

43 participants

Electronic Symptom Follow-up of Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2018-01-01

Completion:

2022-05-31

Conditions

• Cancer

Interventions

• DEVICE

No Results Yet

NCT04076579 | COMPLETED | PHASE2

29 participants

Trabectedin in Combination With Olaparib in Advanced Unresectable or Metastatic Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2020-03-17

Completion:

2023-01-30

Conditions

• Sarcoma
• Sarcoma Metastatic

Interventions

• DRUG

Results Available

NCT04053114 | WITHDRAWN

0 participants

MOLecular Characterization and Treatment of THYroid Carcinoma on Struma Ovarii

Study Type:

OBSERVATIONAL

Last Updated:

2025-08-29

Start Date:

2019-01-01

Completion:

2020-12-31

Conditions

• Ovarian Cancer

Interventions

• OTHER

No Results Yet

NCT03928938 | COMPLETED | NA

43 participants

Follow-up of Cancer Patients Receiving Immune Checkpoint Inhibitor Therapy by Electronic Patient Reported Outcomes-tool

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2017-06-01

Completion:

2022-12-31

Conditions

• Cancer

Interventions

• DEVICE

No Results Yet

NCT03900026 | COMPLETED | PHASE4

782 participants

Effect of Evolocumab on Saphenous Vein Graft Patency Following Coronary Artery Bypass Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2019-05-30

Completion:

2025-01-30

Conditions

• Coronary Artery Bypass Graft Surgery
• Atherosclerosis
• Vein Occlusion

Interventions

• DRUG
• OTHER

No Results Yet

NCT03893630 | COMPLETED | PHASE2

208 participants

Role of ASpirin in Placental and Maternal Endothelial Cell Regulation IN Pre-eclampsia

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2019-04-25

Completion:

2022-07-26

Conditions

• Pre-Eclampsia

Interventions

• DRUG
• OTHER

Results Available

NCT03851120 | COMPLETED | PHASE2

314 participants

Brain Probiotic and LC-PUFA Intervention for Optimum Early Life

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2019-10-31

Completion:

2022-08-31

Conditions

• Maternal Exposure
• Health Behavior
• Infant Development
• Child Development

Interventions

• DIETARY_SUPPLEMENT
• BEHAVIORAL

No Results Yet

NCT03765736 | TERMINATED

199 participants

Genetic Testing in Screening Patients With Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE Trial

Study Type:

OBSERVATIONAL

Last Updated:

2025-08-29

Start Date:

2020-04-20

Completion:

2023-12-01

Conditions

• Metastatic Colon Adenocarcinoma
• Metastatic Rectal Adenocarcinoma
• Stage III Colon Cancer AJCC v8
• Stage III Rectal Cancer AJCC v8
• Stage IIIA Colon Cancer AJCC v8
• Stage IIIA Rectal Cancer AJCC v8
• Stage IIIB Colon Cancer AJCC v8
• Stage IIIB Rectal Cancer AJCC v8
• Stage IIIC Colon Cancer AJCC v8
• Stage IIIC Rectal Cancer AJCC v8
• Stage IV Colon Cancer AJCC v8
• Stage IV Rectal Cancer AJCC v8
• Stage IVA Colon Cancer AJCC v8
• Stage IVA Rectal Cancer AJCC v8
• Stage IVB Colon Cancer AJCC v8
• Stage IVB Rectal Cancer AJCC v8
• Stage IVC Colon Cancer AJCC v8
• Stage IVC Rectal Cancer AJCC v8
• Unresectable Colon Adenocarcinoma
• Unresectable Rectal Adenocarcinoma

Interventions

• OTHER

Results Available

NCT03739892 | COMPLETED | NA

23 participants

Biomarkers to Predict Gain From Therapy in Motor Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2019-01-08

Completion:

2021-06-26

Conditions

• Stroke
• Motor Activity
• Biomarker

Interventions

• BEHAVIORAL

No Results Yet

NCT03724994 | COMPLETED

201 participants

Chemotherapy, Host Response and Molecular Dynamics in Periampullary Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2025-08-29

Start Date:

2018-10-30

Completion:

2024-12-31

Conditions

• Periampullary Adenocarcinoma
• Periampullary Cancer
• Pancreatic Cancer

Interventions

• DRUG

No Results Yet

NCT03715205 | COMPLETED | PHASE4

150 participants

Study to Evaluate the Safety of Pembrolizumab in Participants With Unresectable or Metastatic Melanoma or Non-small Cell Lung Cancer in India (MK-3475-593/KEYNOTE-593)

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2019-01-31

Completion:

2024-08-21

Conditions

• Carcinoma, Non-Small-Cell Lung
• Melanoma

Interventions

• DRUG

Results Available

NCT03695471 | COMPLETED | PHASE2

9 participants

Pembrolizumab in Treating Patients With Stage IB-IV Mycosis Fungoides

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2020-02-04

Completion:

2023-06-21

Conditions

• Mycosis Fungoides
• Sezary Syndrome
• Stage IB Mycosis Fungoides and Sezary Syndrome AJCC v8
• Stage II Mycosis Fungoides and Sezary Syndrome AJCC v8
• Stage IIA Mycosis Fungoides and Sezary Syndrome AJCC v8
• Stage IIB Mycosis Fungoides and Sezary Syndrome AJCC v8
• Stage III Mycosis Fungoides and Sezary Syndrome AJCC v8
• Stage IIIA Mycosis Fungoides and Sezary Syndrome AJCC v8
• Stage IIIB Mycosis Fungoides and Sezary Syndrome AJCC v8
• Stage IV Mycosis Fungoides and Sezary Syndrome AJCC v8
• Stage IVA1 Mycosis Fungoides and Sezary Syndrome AJCC v8
• Stage IVA2 Mycosis Fungoides and Sezary Syndrome AJCC v8
• Stage IVB Mycosis Fungoides and Sezary Syndrome AJCC v8

Interventions

• BIOLOGICAL

Results Available

NCT03596268 | COMPLETED

284 participants

Functional Imaging Reserve in NeuroHIV

Study Type:

OBSERVATIONAL

Last Updated:

2025-08-29

Start Date:

2018-11-20

Completion:

2025-04-30

Conditions

• HIV

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03567733 | COMPLETED

1000 participants

Prospective Registry of Patients Over 75 Years Old Treated With Xience Sierra Stents. Sierra 75 Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-08-29

Start Date:

2018-06-18

Completion:

2020-09-01

Conditions

• Ischemic Heart Disease
• Coronary Artery Disease

Interventions

• DEVICE

No Results Yet

NCT03501979 | TERMINATED | PHASE2

17 participants

Tucatinib, Trastuzumab, and Capecitabine for the Treatment of HER2+ LMD

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2019-02-20

Completion:

2021-06-22

Conditions

• Metastatic Breast Cancer
• Leptomeningeal Disease

Interventions

• DRUG

Results Available

NCT03300557 | COMPLETED | PHASE2

40 participants

Exemestane in Treating Patients With Complex Atypical Hyperplasia of the Endometrium/Endometrial Intraepithelial Neoplasia or Low Grade Endometrial Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2017-11-15

Completion:

2023-12-13

Conditions

• Atypical Hyperplasia
• Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia
• Endometrial Carcinoma
• FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma
• FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma

Interventions

• DRUG
• OTHER

Results Available

NCT03211546 | COMPLETED

322 participants

Pediatric Femur Fracture Registry

Study Type:

OBSERVATIONAL

Last Updated:

2025-08-29

Start Date:

2018-03-14

Completion:

2024-06-10

Conditions

• Femoral Shaft Fracture

Interventions

• PROCEDURE

No Results Yet

NCT03093350 | COMPLETED | PHASE2

12 participants

TACTIC - TAA Specific Cytotoxic T Lymphocytes in Patients With Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-08-29

Start Date:

2017-10-10

Completion:

2019-05-30

Conditions

• Breast Cancer

Interventions

• BIOLOGICAL

Results Available