MedTrace Logo

Functional Imaging Reserve in NeuroHIV

NCT03596268 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 284

Last updated 2025-08-29

No results posted yet for this study

Summary

The purpose of this research study is to look at the brain's efficiency and ability to make up for deficits in the front of the brain to see if people living with HIV (PLWH) are still able to perform well on various cognitive tasks even though there are other underlying processes at work, like inflammation, that affect the brain in a negative way. Results of this study may provide insight into the pathophysiology of disease and may reveal arenas for future possible interventions in PLWH who have impaired neuropsychological performance.

Conditions

Interventions

DIAGNOSTIC_TEST

Imaging

3T Prisma MRI

DIAGNOSTIC_TEST

Serum Laboratory Tests

Blood (plasma and cellular) will be collected.

DIAGNOSTIC_TEST

Lumbar Puncture

CSF will be collected

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • University of Missouri, St. Louis

    collaborator OTHER

  • Temple University

    collaborator OTHER

  • University of California, San Diego

    collaborator OTHER

  • Washington University School of Medicine

    lead OTHER

Principal Investigators

  • Beau M Ances, MD, PhD · Washington University School of Medicine

Eligibility

Min Age
20 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-11-20
Primary Completion
2025-04-30
Completion
2025-04-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03596268 on ClinicalTrials.gov