Clinical Trials

NCT03189719 | COMPLETED | PHASE3

749 participants

First-line Esophageal Carcinoma Study With Pembrolizumab Plus Chemo vs. Chemo (MK-3475-590/KEYNOTE-590)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2017-07-25

Completion:

2020-07-02

Conditions

• Esophageal Neoplasms

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT03164993 | COMPLETED | PHASE2

68 participants

Atezolizumab Combined with Immunogenic Chemotherapy in Patients with Metastatic Triple-negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2017-06-01

Completion:

2023-04-25

Conditions

• Cancer, Breast
• Triple Negative Breast Cancer

Interventions

• DRUG
• OTHER

No Results Yet

NCT03151174 | COMPLETED | EARLY_PHASE1

68 participants

Effects of Vitamin D Supplementation on Strength, Bone Density, and Injury Risk in Collegiate Athletes

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2017-04-29

Completion:

2018-05-15

Conditions

• Vitamin D Deficiency

Interventions

• DRUG

No Results Yet

NCT03140969 | COMPLETED | PHASE1/PHASE2

11 participants

Study to Evaluate QR-110 in Leber's Congenital Amaurosis (LCA) Due to the c.2991+1655A>G Mutation (p.Cys998X) in the CEP290 Gene

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2017-10-16

Completion:

2019-10-02

Conditions

• Leber's Congenital Amaurosis

Interventions

• DRUG

Results Available

NCT03100461 | COMPLETED | NA

500 participants

Adaptive Intervention to Maximize Colorectal Screening in Safety Net Populations

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2018-01-22

Completion:

2022-08-31

Conditions

• Colorectal Cancer

Interventions

• OTHER

No Results Yet

NCT03092011 | ACTIVE_NOT_RECRUITING | PHASE4

69 participants

Treatment of Neonatal Abstinence Syndrome With Clonidine Versus Morphine as Primary Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2018-02-21

Completion:

2024-10-01

Conditions

• Neonatal Abstinence Syndrome

Interventions

• DRUG

No Results Yet

NCT03077061 | ACTIVE_NOT_RECRUITING | NA

140 participants

Peri-implantitis - Reconstructive Surgical Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2017-04-01

Completion:

2022-03-14

Conditions

• Peri-Implantitis

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT03048825 | COMPLETED | PHASE3

7264 participants

Colchicine and Spironolactone in Patients with MI / SYNERGY Stent Registry

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2018-02-01

Completion:

2024-08-09

Conditions

• ST Elevation Myocardial Infarction
• Non ST Elevation Myocardial Infarction

Interventions

• DRUG
• DEVICE

No Results Yet

NCT03037749 | COMPLETED | EARLY_PHASE1

42 participants

Over-arousal as a Mechanism Between Alcohol and Intimate Partner Violence

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2015-09-27

Completion:

2018-08-31

Conditions

• Domestic Violence
• Alcohol Consumption

Interventions

• DRUG

No Results Yet

NCT03004183 | COMPLETED | PHASE2

57 participants

SBRT and Oncolytic Virus Therapy Before Pembrolizumab for Metastatic TNBC and NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2017-07-01

Completion:

2022-07-22

Conditions

• Metastatic Non-small Cell Lung Cancer
• Metastatic Triple-negative Breast Cancer

Interventions

• BIOLOGICAL
• DRUG
• RADIATION

Results Available

NCT02987738 | COMPLETED | PHASE1

30 participants

Pilot Study to Explore the Efficacy of DAPAglifozin as add-on to Closed-loop Control in Patients With Type 1 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2017-02-09

Completion:

2017-12-19

Conditions

• Type1diabetes

Interventions

• DRUG

No Results Yet

NCT02941055 | COMPLETED | NA

56 participants

ADIRA (Anti-inflammatory Diet In Rheumatoid Arthritis)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2017-02-01

Completion:

2018-05-09

Conditions

• Rheumatoid Arthritis

Interventions

• OTHER

No Results Yet

NCT02918942 | COMPLETED

25 participants

Tympanoseal (Tympanic Membrane Device) Clinical Study

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2016-10-04

Completion:

2021-09-30

Conditions

• Tympanic Membrane Perforation

Interventions

• DEVICE

Results Available

NCT02914886 | COMPLETED | PHASE4

14 participants

Beneficial Effect of Insulin Glulisine by Lipoatrophy and Type 1 Diabetes (LAS)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2016-09-30

Completion:

2019-04-30

Conditions

• Type 1 Diabetes
• Lipoatrophy

Interventions

• DRUG

No Results Yet

NCT02873052 | COMPLETED

200 participants

MyoVista Measurements in Patients With Atherosclerosis and CAD

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-15

Start Date:

2015-09-01

Completion:

2019-09-22

Conditions

• Coronary Artery Disease (CAD)
• Atherosclerosis

Interventions

• DEVICE

No Results Yet

NCT02836249 | COMPLETED | PHASE3

181 participants

Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Positive Hepatitis B (China)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2015-06-19

Completion:

2017-03-21

Conditions

• HBV
• Chronic HBV Infection

Interventions

• DRUG

Results Available

NCT02810405 | COMPLETED

191 participants

Collection of Tissue Blocks or Slides From Patients With Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-15

Start Date:

2011-10-03

Completion:

2024-08-26

Conditions

• Tumor
• Carcinogens
• Neoplasm, Benign
• Benign Neoplasms
• Cancer

No Results Yet

NCT02776735 | COMPLETED | PHASE2

102 participants

An Open-label, Ascending, Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Polyarticular-course Juvenile Idiopathic Arthritis (pcJIA)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2016-09-06

Completion:

2022-04-08

Conditions

• Juvenile Idiopathic Arthritis

Interventions

• DRUG

Results Available

NCT02748798 | TERMINATED | EARLY_PHASE1

10 participants

Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2020-11-10

Completion:

2021-10-16

Conditions

• Lung Transplant
• Lung Resection
• Lung Cancer
• Asthma
• Cystic Fibrosis
• Chronic Obstructive Pulmonary Disease
• Emphysema
• Mesothelioma
• Asbestosis
• Pulmonary Embolism
• Interstitial Lung Disease
• Pulmonary Fibrosis
• Bronchiectasis
• Seasonal Allergies
• Cold Virus
• Lung Infection
• Pulmonary Hypertension
• Pulmonary Dysplasia
• Obstructive Sleep Apnea

Interventions

• DRUG
• DEVICE

No Results Yet

NCT02695277 | COMPLETED | NA

146 participants

Combined Endoscopic Epicardial and Percutaneous Endocardial Ablation Versus Repeated Catheter Ablation in Persistent and Longstanding Persistent Atrial Fibrillation

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2015-11-30

Completion:

2022-11-30

Conditions

• Atrial Fibrillation
• Persistent and Longstanding Persistent Atrial Fibrillation

Interventions

• DEVICE

No Results Yet

NCT02638519 | TERMINATED | EARLY_PHASE1

51 participants

HP Xenon-129 fMRI of Healthy Volunteers and Participants With Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2016-06-27

Completion:

2022-04-19

Conditions

• Alzheimer Disease

Interventions

• OTHER
• DRUG
• DEVICE

No Results Yet

NCT02614248 | COMPLETED | NA

149 participants

The Use of Coconut Oil for the Prevention and Treatment of Diaper Dermatitis in the NICU Population

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2016-01-31

Completion:

2019-06-30

Conditions

• Dermatitis, Contact

Interventions

• OTHER

Results Available

NCT02607722 | COMPLETED

10117 participants

All-Case Surveillance of Ofev in Patients With IPF in Japan

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-15

Start Date:

2015-08-31

Completion:

2023-05-02

Conditions

• Idiopathic Pulmonary Fibrosis

Interventions

• DRUG

Results Available

NCT02598973 | COMPLETED | NA

9 participants

Effect of Exercise in Parkinsonism

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2016-02-01

Completion:

2022-01-31

Conditions

• Parkinson's Disease
• Drug-induced Parkinsonism

Interventions

• BEHAVIORAL

Results Available

NCT02592863 | TERMINATED | NA

26 participants

Trental for the Treatment of Vertigo/Dizziness/Imbalance

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2015-01-31

Completion:

2020-12-31

Conditions

• Dizziness
• Vertigo

Interventions

• DRUG

Results Available

NCT02516813 | COMPLETED | PHASE1

52 participants

Phase 1 Trial of MSC2490484A, an Inhibitor of a DNA-dependent Protein Kinase, in Combination With Radiotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2015-09-15

Completion:

2021-03-26

Conditions

• Advanced Solid Tumors

Interventions

• DRUG
• RADIATION

Results Available

NCT02507934 | COMPLETED | NA

40 participants

Tolerability, Safety and Efficacy of Lubricin Versus Sodium Hyaluronate Eye Drops in Patients With Moderate Dry Eye

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2015-06-26

Completion:

2015-10-05

Conditions

• Dry Eye Syndrome

Interventions

• DEVICE

Results Available

NCT02376010 | COMPLETED | PHASE4

110 participants

Rivaroxaban Versus Warfarin in the Evaluation of Progression of Coronary Calcium

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2015-04-02

Completion:

2018-04-01

Conditions

• Atherosclerosis

Interventions

• DRUG

Results Available

NCT02310269 | COMPLETED

152 participants

Long Term Safety and Efficacy of Pasireotide s.c. in Patients With Cushing's Disease

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-15

Start Date:

2013-03-28

Completion:

2023-07-10

Conditions

• Cushings Disease

Interventions

• DRUG

Results Available

NCT02236910 | ACTIVE_NOT_RECRUITING | PHASE2

66 participants

An Open Label Registry Study of Lutetium-177 (DOTA0, TYR3) Octreotate (Lu-DOTA-TATE) Treatment in Patients with Somatostatin Receptor Positive Tumours

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2014-07-31

Completion:

2025-12-31

Conditions

• Neuroendocrine Carcinoma

Interventions

• OTHER

No Results Yet

NCT02170519 | TERMINATED | PHASE4

27 participants

Inhaled Aerosolized Prostacyclin for Pulmonary Hypertension Requiring Inhaled Nitric Oxide

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2006-09-30

Completion:

2009-01-31

Conditions

• Pulmonary Hypertension

Interventions

• DRUG

Results Available

NCT02096354 | COMPLETED | PHASE2

62 participants

A Phase 2 Randomized, Open-Label Study of RRx-001 vs Regorafenib in Subjects With Metastatic Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2014-05-31

Completion:

2018-04-13

Conditions

• Colorectal Neoplasms

Interventions

• DRUG

Results Available

NCT02033941 | TERMINATED | PHASE2

10 participants

Phase 2 Study to Examine Grape Seed Extract as an Anti-Oligomerization Agent in Alzheimer's Disease (AD)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2018-07-03

Completion:

2019-10-04

Conditions

• Alzheimer's Disease

Interventions

• DRUG

No Results Yet

NCT02014103 | COMPLETED | PHASE4

71 participants

Conversion From Brand to Generic Tacrolimus in High Risk Transplant Recipients

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2015-03-31

Completion:

2015-08-31

Conditions

• Complication of Transplant

Interventions

• DRUG

Results Available

NCT01969058 | COMPLETED | PHASE2

76 participants

Effect of Isotretinoin on Immune Activation Among HIV-1 Infected Subjects With Incomplete CD4+ T Cell Recovery

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2014-07-02

Completion:

2016-08-31

Conditions

• HIV-1 Infection

Interventions

• DRUG

Results Available

NCT01854762 | TERMINATED | PHASE2/PHASE3

33 participants

Antiretroviral Regimens Containing Raltegravir for Prophylaxis of Mother-to-child-transmission of HIV Infection

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2015-06-01

Completion:

2017-08-02

Conditions

• HIV
• Pregnancy

Interventions

• DRUG

Results Available

NCT01838733 | COMPLETED

146 participants

Cerebral Oximetry and Perioperative Outcome in Non-Cardiac Surgery

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-15

Start Date:

2014-04-30

Completion:

2018-10-31

Conditions

• High Risk Non-cardiac Surgery
• Death
• Delirium
• Kidney Injury
• Myocardial Infarction
• Respiratory Failure
• Postoperative Infection

Interventions

• OTHER

No Results Yet

NCT01661387 | TERMINATED

3258 participants

A European Post-Authorisation Observational Study (Registry) of Patients With Chronic Adrenal Insufficiency (AI)

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-15

Start Date:

2012-08-07

Completion:

2020-10-31

Conditions

• Chronic Adrenal Insufficiency

No Results Yet

NCT01587196 | COMPLETED | PHASE2

72 participants

CURE Addiction Center of Excellence: Brain Mechanisms of Relapse and Recovery

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2012-01-31

Completion:

2021-01-01

Conditions

• Prescription Opiate/Medication Dependence

Interventions

• DRUG

Results Available

NCT01556334 | WITHDRAWN | PHASE3

0 participants

Erythromycin Versus Azithromycin in Preterm Premature Rupture of Membranes

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-15

Start Date:

2010-04-30

Completion:

2012-10-31

Conditions

• Preterm Premature Ruptured Membranes

Interventions

• DRUG

No Results Yet