Clinical Trials

NCT00001043 | COMPLETED | PHASE1

20 participants

A Phase I, Multicenter, Randomized Trial to Evaluate the Safety and Immunogenicity of Vaccinia-Derived MN HIV-1 Recombinant Envelope Glycoprotein (rgp160) of Human Immunodeficiency Virus at Two Different Vaccination Schedules

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections
• HIV Seronegativity

Interventions

• BIOLOGICAL

No Results Yet

NCT00001042 | COMPLETED | PHASE1

112 participants

A Phase I, Randomized, Double-Blind, Placebo-Controlled, Clinical Trial to Compare the Safety and Immunogenicity of Recombinant Envelope Protein rgp120/HIV-1SF2 (BIOCINE) Combined With Seven Adjuvants in Healthy HIV-1 Uninfected Individuals

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• BIOLOGICAL

No Results Yet

NCT00001037 | COMPLETED | PHASE1

22 participants

A Phase I, Multicenter, Clinical Trial to Evaluate the Safety and Immunogenicity of Vaccinia-Derived MN HIV-1 Recombinant Envelope Glycoprotein (rgp160) of Human Immunodeficiency Virus at Two Different Vaccination Schedules

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• BIOLOGICAL

No Results Yet

NCT00001034 | COMPLETED | PHASE2

850 participants

The Safety and Effectiveness of Ganciclovir in the Prevention of Cytomegalovirus (CMV) of the Eyes and Disease of the Stomach and Intestines in Patients With HIV

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• Cytomegalovirus Retinitis
• HIV Infections
• Gastrointestinal Diseases

Interventions

• DRUG

No Results Yet

NCT00001033 | COMPLETED | PHASE3

650 participants

The Treatment of Tuberculosis in HIV-Infected Patients

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections
• Tuberculosis

Interventions

• DRUG

No Results Yet

NCT00001032 | COMPLETED | PHASE2

180 participants

A Study of Dideoxycytidine Plus Zidovudine (AZT) in HIV-Infected Children Who Have Taken AZT

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00001031 | COMPLETED | PHASE2

296 participants

A Phase II Clinical Trial to Evaluate the Immunogenicity and Reactogenicity of the Recombinant HIV-1 Envelope Vaccines SF-2 rgp120 (CHO) [Chiron Vaccines] in MF59 Adjuvant and MN rgp120/HIV-1 [VaxGen] in Alum Adjuvant in Healthy Adults

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• BIOLOGICAL

No Results Yet

NCT00001029 | COMPLETED | PHASE2

654 participants

A Comparison of Three Treatments for Advanced HIV Disease in Patients Who Have Received Nucleoside Therapy in the Past

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00001026 | COMPLETED | PHASE1

56 participants

A Phase I, Multicenter, Randomized Trial to Evaluate the Safety and Immunogenicity of a Recombinant Vaccinia-HIV Envelope Vaccine (HIVAC-1e) in Combination With a Panel of Subunit Recombinant HIV Envelope Vaccines in Vaccinia-Naive Individuals

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• BIOLOGICAL

No Results Yet

NCT00001022 | COMPLETED | PHASE3

1200 participants

A Comparison of Zidovudine (AZT) Used Alone or in Combination With Didanosine (ddI) or Dideoxycytidine (ddC) in HIV-Infected Patients

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00001014 | COMPLETED | PHASE3

302 participants

Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• Pneumonia, Pneumocystis Carinii
• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00001013 | COMPLETED | PHASE3

364 participants

Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• Pneumonia, Pneumocystis Carinii
• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00001011 | COMPLETED | PHASE3

538 participants

The Safety and Effectiveness of Zidovudine in the Treatment of Patients With Early AIDS Related Complex

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00001010 | COMPLETED | PHASE1

72 participants

A Study of Zidovudine Plus Acyclovir in HIV-Infected Patients

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00001005 | COMPLETED | PHASE1

30 participants

A Study of Zidovudine Plus Interleukin-2 in HIV-Infected Patients Who Have No Symptoms of Infection But Who Have Tender Lymph Nodes

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00001004 | COMPLETED | PHASE2

30 participants

A Study of Tumor Necrosis Factor and Human Interferon-gamma in Patients With AIDS Related Complex

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00001003 | COMPLETED | NA

20 participants

A Study of Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• Pneumonia, Pneumocystis Carinii
• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00001002 | COMPLETED | PHASE1

12 participants

A Study of Foscarnet in the Treatment of HIV Infection in Patients Who Have Taken Zidovudine for a Long Time

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00001001 | COMPLETED | NA

39 participants

A Study of Zidovudine in HIV-Infected Patients With Liver Disease

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections
• Liver Diseases

Interventions

• DRUG

No Results Yet

NCT00000999 | COMPLETED | PHASE1

500 participants

The Safety and Effectiveness of Zidovudine (AZT) in the Treatment of HIV Infection in Patients With AIDS and Advanced ARC

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00000998 | COMPLETED | PHASE1

50 participants

A Study of Trimetrexate in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Not Previously Treated for PCP

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• Pneumonia, Pneumocystis Carinii
• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00000997 | COMPLETED | NA

12 participants

A Study of Dideoxycytidine in HIV-Infected Patients

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00000996 | COMPLETED | PHASE2

48 participants

A Study of Doxorubicin in the Treatment of AIDS-Related Kaposi's Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• Sarcoma, Kaposi
• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00000995 | COMPLETED | NA

60 participants

A Study of AZT Plus Ganciclovir in Patients With AIDS and Cytomegalovirus (CMV) Infection

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• Cytomegalovirus Infections
• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00000994 | COMPLETED | PHASE3

240 participants

A Study of AZT in HIV-Infected Patients With AIDS-Related Kaposi's Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00000991 | COMPLETED | PHASE3

600 participants

A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected Patients

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• Pneumonia, Pneumocystis Carinii
• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00000989 | COMPLETED | NA

50 participants

The Safety and Effectiveness of Ganciclovir Used Alone or in Combination With Granulocyte-Macrophage Colony Stimulating Factor in the Treatment of Cytomegalovirus (CMV) of the Eye in Patients With AIDS

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• Cytomegalovirus Retinitis
• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00000987 | COMPLETED | PHASE1

36 participants

A Study of Chemotherapy Plus Azidothymidine in the Treatment of Kaposi's Sarcoma in Patients With AIDS

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• Sarcoma, Kaposi
• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00000986 | COMPLETED | PHASE1

18 participants

The Safety and Effectiveness of Interleukin-2 Plus Zidovudine in Patients With AIDS or AIDS Related Complex

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00000985 | COMPLETED | PHASE3

26 participants

Comparison of Foscarnet Versus Vidarabine in the Treatment of Herpes Infection in Patients With AIDS Who Have Not Had Success With Acyclovir

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• Herpes Simplex
• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00000983 | COMPLETED | PHASE2

400 participants

The Safety of Different Dose Levels of Zidovudine in HIV-Infected Children

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00000977 | COMPLETED | PHASE1

52 participants

Active Immunization of Asymptomatic, HIV-Infected Individuals With Recombinant GP160 HIV-1 Antigen: A Phase I/II Study of Immunogenicity and Toxicity

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• BIOLOGICAL

No Results Yet

NCT00000975 | COMPLETED | PHASE2

30 participants

A Study of Itraconazole in the Treatment and Prevention of Histoplasmosis, a Fungal Infection, in Patients With AIDS

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections
• Histoplasmosis

Interventions

• DRUG

No Results Yet

NCT00000973 | COMPLETED | PHASE1

26 participants

A Study of Pyrimethamine in the Treatment of Infection by a Certain Parasite in HIV-Positive Patients

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• Toxoplasmosis, Cerebral
• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00000972 | COMPLETED | PHASE1

64 participants

A Phase I Clinical Trial to Evaluate: Part A. The Safety of MTP-PE/MF59 Adjuvant Emulsion. Part B. The Safety and Immunogenicity of Env 2-3, a Yeast Derived Recombinant Envelope Protein of Human Immunodeficiency Virus-1, in Combination With MTP-PE/MF59

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections
• HIV Seronegativity

Interventions

• BIOLOGICAL

No Results Yet

NCT00000970 | COMPLETED | PHASE1

30 participants

A Study of Foscarnet Plus Ganciclovir in the Treatment of Cytomegalovirus of the Eye in Patients With AIDS Who Have Already Been Treated With Ganciclovir

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• Cytomegalovirus Retinitis
• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00000969 | COMPLETED | NA

400 participants

A Prospective, Randomized, Open-Label, Comparative Trial of Dideoxyinosine (ddI) Versus Dideoxycytidine (ddC) in HIV-Infected Patients Who Are Intolerant of or Who Have Failed Zidovudine (AZT) Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00000968 | COMPLETED | PHASE1

60 participants

A Phase I Multicenter Clinical Trial to Evaluate the Safety and Immunogenicity of Vaccinia-Derived HIV-1 Recombinant Envelope Glycoprotein (gp160)

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections

Interventions

• BIOLOGICAL

No Results Yet

NCT00000961 | TERMINATED | PHASE2

112 participants

The Safety and Effectiveness of Hyperimmune Anti-HIV Intravenous Immunoglobulin (HVIG) Plus Zidovudine in HIV-Infected Infants

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Completion:

1991-05-31

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT00000959 | COMPLETED | NA

600 participants

Prophylaxis Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Suspected Latent Tuberculous Infection

Study Type:

INTERVENTIONAL

Last Updated:

2021-11-04

Conditions

• HIV Infections
• Tuberculosis

Interventions

• DRUG

No Results Yet