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Effort of Breathing and Dyssynchrony Burden During Assisted Ventilation in Paediatric Patients

NCT07796321 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25

Last updated 2026-09-01

No results posted yet for this study

Summary

The goal of this trial is to learn if one mode of mechanical ventilation (i.e. machine to help with breathing) is better than another in children who need help from a machine to breathe. The main questions it aims to answer are:

* How hard do children need to work to breathe when they are using different types of modes of mechanical ventilation?
* Evaluate which mode of mechanical ventilation performs better when the patient is clinically awake enough to start breaths

Conditions

  • Mechanical Ventilation
  • Paediatric Intensive Care
  • Paediatric Dysfunctional Breathing

Interventions

DEVICE

Pressure Control Mode

In pressure control mode every breath is controlled by the ventilator, including when the breaths are delivered. This mode is typically used when patients are sedated and unable to breathe on their own.

DEVICE

Pressure Support Mode

In pressure support mode every breath is initiated and controlled by the patient. This mode is used when patients are awake enough to take all breaths on their own.

Sponsors & Collaborators

  • The Hospital for Sick Children

    lead OTHER

Principal Investigators

  • Luciana Rodriguez Guerineau, M.D. · The Hospital for Sick Children

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
CROSSOVER

Eligibility

Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-09-21
Primary Completion
2028-03-31
Completion
2028-03-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07796321 on ClinicalTrials.gov