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Prospective Multiomic Analysis in Small-Cell Lung Cancer

NCT07795411 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2026-08-31

No results posted yet for this study

Summary

This is an observational study to collects blood samples and tumor tissue from adults with relapsed small-cell lung cancer (SCLC) receicing standard of care commercial DLL3 T cell engager. The goal of the study is to understand the changes in tumor markers over time and examine whether these changes are associated with clinical outcomes. Participants will provide blood samples and, when clinically feasible, tumor tissue during routine care visits, treatment, and imaging assessments. The study does not assign cancer treatment.

Conditions

  • Small Cell Cancer Of The Lung
  • Small Cell Lung Cancer ( SCLC )
  • Lung Cancer
  • Small-Cell Lung Cancer (SCLC)

Interventions

PROCEDURE

Biospecimen collection

Undergo blood and tissue sample collection

Sponsors & Collaborators

  • Genentech, Inc.

    collaborator INDUSTRY

  • Ohio State University Comprehensive Cancer Center

    lead OTHER

Principal Investigators

  • Asrar Alahmadi, MBBS, MAS-CR · Ohio State University Comprehensive Cancer Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-11-25
Primary Completion
2028-12-31
Completion
2028-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07795411 on ClinicalTrials.gov