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Polynucleotide-Hyaluronic Acid Gel With Xenograft for Alveolar Ridge Preservation

NCT07771257 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2026-08-18

No results posted yet for this study

Summary

This randomized controlled clinical trial will evaluate the efficacy of polynucleotide-hyaluronic acid gel combined with xenograft and collagen membrane for alveolar ridge preservation following tooth extraction. Twenty participants will be randomly allocated into two parallel groups. The test group will receive xenograft mixed with polynucleotide-hyaluronic acid gel and covered with a collagen membrane, while the control group will receive xenograft with a collagen membrane alone. Clinical and CBCT assessments will be performed at baseline and during follow-up. After 6 months, ridge dimensional changes will be evaluated and core biopsies will be obtained at the time of implant placement for histological assessment.

Conditions

  • Alveolar Ridge Preservation

Interventions

OTHER

Polynucleotide-Hyaluronic Acid Gel With Xenograft

Xenograft mixed with polynucleotide-hyaluronic acid gel and covered with a collagen membrane for alveolar ridge preservation after tooth extraction.

OTHER

Xenograft With Collagen Membrane

Xenograft placed in the extraction socket and covered with a collagen membrane for alveolar ridge preservation after tooth extraction.

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Principal Investigators

  • Maryam Alabbas, BDS · Cairo University

  • Manal Hosni · Cairo University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-09-30
Primary Completion
2027-04-30
Completion
2027-04-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07771257 on ClinicalTrials.gov