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Success Rates and Safety of Steroid Injections in Managing Spinal and Sacro-Iliac Pain (CORTisone Injection Spine Study)

NCT07762170 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 500

Last updated 2026-08-13

No results posted yet for this study

Summary

This study aims to analyze the efficacy and safety of different kinds of steroid injections for back pain, comparing different steroids, dosages, locations (epidural, facet joints, nerve blocks), and also the difference between injections with steroids and local anesthetics, to optimize this treatment that is currently not standardized. The investigators will compare retrospectively and prospectively the efficacy of different injections in the same patients, using mainly a parameter called integral of pain relief, which combines the percentage of pain relief provided by a treatment and its duration over time, as well as improvements in functionality.

Conditions

  • Back Pain Lower Back
  • Neck Pain
  • Radiculopathy Multiple Sites
  • Spinal Stenosis Cervicothoracic Region
  • Spinal Stenosis Lumbar
  • Failed Back Surgery Syndrome (FBSS)
  • Sciatica
  • Intervertebral Disc Disorders With Radiculopathy, Lumbar Region
  • Spine Osteoarthritis

Interventions

DRUG

triamcinolone acetonide (Kenalog)

Comparison of efficacy and safety of various protocols of injections for back pain

DRUG

Celestone Soluspan 6Mg/Ml Suspension for Injection

Comparison of efficacy and safety of various protocols of injections for back pain

DRUG

Depo-Medrol 40Mg/Ml Suspension for Injection

Comparison of efficacy and safety of various protocols of injections for back pain

DRUG

Dexamethasone

Comparison of efficacy and safety of various protocols of injections for back pain

Sponsors & Collaborators

  • Igor Wilderman. MD

    lead OTHER

Principal Investigators

  • Igor Wilderman, MD · Canadian Centre for Clinical Trials

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-07-30
Primary Completion
2029-12-31
Completion
2030-03-31
FDA Drug
Yes

Countries

  • Canada

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07762170 on ClinicalTrials.gov