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Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression

NCT05058287 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2026-04-28

No results posted yet for this study

Summary

This study seeks to evaluate the impact of intra-operative topical epidural steroid usage in patients undergoing 1-2 level lumbar laminectomy. The study will examine post-operative opioid usage, length of stay, return to work, and patient reported outcomes following these procedures.

Conditions

  • Opioid Use
  • Lumbar Spinal Stenosis
  • Pain, Postoperative
  • Pain, Back

Interventions

DRUG

Depo-Medrol 40Mg/Ml Suspension for Injection

40mg Depo-Medrol mixed with hemostatic matrix

DRUG

Placebo

1 mL of sterile normal saline mixed with hemostatic matrix

Sponsors & Collaborators

  • Hospital for Special Surgery, New York

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-11-05
Primary Completion
2026-12-31
Completion
2026-12-31
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05058287 on ClinicalTrials.gov