Peripheral Blood Lipidomic and Ceramide Profiles in Atrial Fibrillation
NCT07757282 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2026-08-11
Summary
This prospective multi-cohort observational study evaluates the association between peripheral blood lipidomic and ceramide profiles and atrial fibrillation. The study hypothesis is that peripheral blood lipidomic features and ceramide-related profiles are associated with the presence of atrial fibrillation. Participants with atrial fibrillation and control participants with other cardiovascular diseases will be prospectively enrolled. Peripheral blood samples will be analyzed using untargeted lipidomic profiling in one cohort and targeted ceramide assays in another cohort.
Conditions
- Atrial Fibrillation (AF)
Interventions
- OTHER
-
Peripheral blood untargeted lipidomic profiling
Peripheral blood samples from cohort 1 will be analyzed using untargeted lipidomic profiling. No treatment or therapeutic intervention will be assigned by the investigators.
- OTHER
-
Peripheral blood targeted ceramide assay
Peripheral blood samples from cohort 2 will be analyzed using targeted ceramide assays. No treatment or therapeutic intervention will be assigned by the investigators.
Sponsors & Collaborators
-
First Affiliated Hospital Xi'an Jiaotong University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-06-15
- Primary Completion
- 2027-01-31
- Completion
- 2027-02-28
Countries
- China
Study Locations
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