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Micro-nanoplastic Exposure and Coronary Microcirculatory Dysfunction as Well as Cardiovascular Outcomes

NCT07748767 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 184

Last updated 2026-08-06

No results posted yet for this study

Summary

With strict quality control procedures applied throughout microplastic testing, this study will assess the association between baseline circulating micro-nanoplastic exposure and coronary microvascular dysfunction, as well as subsequent long-term cardiovascular outcomes.

Conditions

  • Coronary Microvascular Dysfunction (CMD)
  • Microplastic Exposure
  • Nanoplastics
  • MACE

Interventions

OTHER

micro-nanoplastic examination

In this prospective cohort study, the investigators plan to perform a low-contamination protocol for the detection of circulating micro-nanoplastic particles in eligible subjects prior to the administration of invasive coronary angiography and concomitant coronary microvascular function assessment, so as to clarify the impact of micro-nanoplastic exposure status on coronary microvascular function and long-term prognosis.

PROCEDURE

Microvascular Function Examination

Using a catheter to perform invasive coronary microcirculation functional assessment, including coronary flow reserve (CFR) and index of microcirculation resistance (IMR)

Sponsors & Collaborators

  • Beijing Anzhen Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2027-01-01
Primary Completion
2029-12-31
Completion
2029-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07748767 on ClinicalTrials.gov