EXERT-BC Cardio: Cardio or Conditioning Training With Breast Cancer
NCT07739563 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2026-08-17
Summary
In this study, the investigators hypothesize that observed intense resistance training with conditioning elicits similar changes in body composition, muscle mass, and blood pressure as that with cardiovascular training (or cardio) for women treated with breast cancer.
Conditions
Interventions
- BEHAVIORAL
-
Resistance Training with Cardio
Participants in this arm will engage in a supervised exercise regimen three times per week, for approximately 2 months (8 weeks). The regimen combines two days of hypertrophy-focused resistance training with a third day dedicated to steady-state cardiovascular exercise. The cardio day will utilize ergometer-based exercises (rowing ergometer, Assault Air Bike) and unweighted sled pushes, with each activity lasting 10 minutes continuously. The overall program aims to improve cardiorespiratory fitness and body composition in breast cancer survivors, under the guidance of Certified Strength and Conditioning Specialists (CSCS).
- BEHAVIORAL
-
Resistance Training with Conditioning
Participants in this arm will engage in a supervised exercise regimen three times per week, for approximately 2 months (8 weeks). The regimen combines two days of hypertrophy-focused resistance training with a third day dedicated to high-intensity conditioning. The conditioning day involves a circuit format of 6 total exercises, completed for 8 repetitions each across 8 sets, with limited rest periods (10 seconds or less) between exercises and sets. Exercise selection is total-body focused, alternating between upper and lower body movements. The program aims to improve muscular conditioning and body composition in breast cancer survivors, under the guidance of Certified Strength and Conditioning Specialists (CSCS).
Sponsors & Collaborators
-
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
lead OTHER
Principal Investigators
-
Colin Champ, MD, CSCS · AHN Radiation Oncology
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 20 Years
- Max Age
- 89 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-07-27
- Primary Completion
- 2027-04-30
- Completion
- 2027-07-31
Countries
- United States
Study Locations
More Related Trials
-
EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Breast CA
NCT05747209 ·Status: COMPLETED
-
Resistance Training and Post Workout Protein to Improve Body Composition During Neoadjuvant Chemotherapy for Breast Cancer
NCT06858449 ·Status: RECRUITING ·Phase: NA
-
Strength After Breast Cancer
NCT06052488 ·Status: RECRUITING ·Phase: NA
-
Breast Cancer Exercise Intervention Study
NCT05957068 ·Status: RECRUITING ·Phase: NA
-
Exercise Study for Breast Cancer Survivors
NCT04208074 ·Status: UNKNOWN ·Phase: NA
-
Trial Comparing the Effects of Linear Versus Nonlinear Aerobic Training in Women With Operable Breast Cancer
NCT01186367 ·Status: COMPLETED ·Phase: NA
-
Acute Exercise Intervention in Breast Cancer Survivors
NCT03779867 ·Status: TERMINATED ·Phase: NA
-
Effects of Physical Exercise on Cardio-vascular Efficiency and Quality of Life in Breast Cancer Survivors
NCT04337736 ·Status: COMPLETED ·Phase: NA
-
Inspiratory Muscle Training for Breast Cancer Patients on Chemotherapy
NCT07386444 ·Status: RECRUITING ·Phase: NA
-
Creatine Supplementation and Resistance Training in Patients With Breast Cancer
NCT05878106 ·Status: RECRUITING ·Phase: NA
-
Breast Cancer and Resistance Exercise Program
NCT04562233 ·Status: TERMINATED ·Phase: NA
-
Acute Exercise Cardioprotection From Doxorubicin
NCT02006979 ·Status: COMPLETED ·Phase: PHASE1
-
Nutrition, Exercise, and Breast Cancer Survivorship
NCT01151488 ·Status: COMPLETED ·Phase: NA
-
Different Resistance Training Intensity Prescription and Monitoring Methodologies: Effects on Strength, Body Composition, and Well-being in Survivors of Breast Cancer
NCT06940310 ·Status: COMPLETED ·Phase: NA
-
Effect of Diet and Exercise in Breast Cancer Survivors
NCT01498536 ·Status: COMPLETED ·Phase: NA
-
Diet Restriction and Exercise-induced Adaptations in Metastatic Breast Cancer
NCT03795493 ·Status: COMPLETED ·Phase: NA
-
Resistance and Aerobic Exercise for Prevention in Women With Dense Breasts (REP-D)
NCT06322888 ·Status: RECRUITING ·Phase: NA
-
Exercise Post-Diagnosis of Breast Cancer
NCT04013568 ·Status: COMPLETED ·Phase: NA
-
Effects of Physical Activity in Early Stage Hormone Receptor Positive Breast Cancer Patients
NCT07539038 ·Status: RECRUITING
-
All-extremity Exercise During Breast Cancer Chemotherapy
NCT04914663 ·Status: RECRUITING ·Phase: NA
-
Exercise Program in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy
NCT03280836 ·Status: COMPLETED ·Phase: NA
-
Respiratory Muscle Strength Training to Prevent Respiratory Muscle Weakness in Adults Newly Diagnosed With Breast Cancer
NCT07229378 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Exercise Therapy in Radiation Therapy
NCT03905356 ·Status: COMPLETED ·Phase: NA
-
Exercise and Cognitive (Brain) Function in Breast Cancer Patients Getting Chemotherapy After Breast Surgery
NCT04616300 ·Status: RECRUITING
-
Remotely Supervised Exercise During Chemotherapy in Women With Breast Cancer
NCT07716306 ·Status: NOT_YET_RECRUITING ·Phase: NA