Breast Cancer Exercise Intervention Study
NCT05957068 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 2156
Last updated 2025-09-05
Summary
This is a 24-week exercise programme consisting of aerobic exercise and muscle strength training, 3 sessions per week. The first 9 sessions are supervised by physiotherapists in person, followed by 63 sessions monitored remotely (video) or supervised by trainers at ActiveSG (Sport Singapore) gyms.
Conditions
- Early-stage Breast Cancer
- Locally Advanced Breast Cancer
Interventions
- BEHAVIORAL
-
Exercise Programme
Aerobic exercise consists of 20-minute brisk walks or jogs (5-6 km/h) on the treadmill each session, reaching a heart rate corresponding to 50%-70% of the patient's VO2max (VO2max is determined before embarking on the exercise programme). Study participants are expected to aim for 50% VO2max at the start of the exercise programme, and gradually increasing to 70% VO2max in subsequent exercise sessions. Strength training comprises a series of circuit resistance exercises targeting the major muscle groups. Patients will perform 2-4 sets of these exercises each session, 8-10 repetitions per set. Both aerobic exercise and strength training are done in the same session. With warm-up and cool-down, each session is estimated to take up 1 hour.
- BEHAVIORAL
-
Control
Usual care group.
Sponsors & Collaborators
-
Singapore Cancer Society
collaborator OTHER -
Genome Institute of Singapore
collaborator OTHER -
National University of Singapore
collaborator OTHER -
Singapore General Hospital
collaborator OTHER -
National Cancer Centre, Singapore
lead OTHER
Principal Investigators
-
Dr Elaine LIM, MD, PhD · National Cancer Centre, Singapore
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 21 Years
- Max Age
- 99 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-07-01
- Primary Completion
- 2028-05-31
- Completion
- 2033-05-31
Countries
- Singapore
Study Locations
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