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Dentin Hypersensitivity Reduction Efficacy Clinical

NCT07738198 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 116

Last updated 2026-07-31

No results posted yet for this study

Summary

The objective of this study is to assess clinical efficacy of a toothpaste containing stannous fluoride (Colgate-Palmolive Company, New York, NY, USA) to provide dental hypersensitivity relief (tactile and air blast) in comparison to commercially available potassium-based desensitizing toothpaste (Senodyne Extra Whitening Toothpaste, GasoSmithKline Co., UK) and commercially available non-desensitizing toothpaste (Colgate Cavity Protection Toothpaste, Colgate-Palmolive Company, New York, NY, USA) over a seven day study period

Conditions

  • Dental Hypersensitivity

Interventions

DRUG

5% potassium nitrate

Brush twice daily (morning and evening) Duration of exposure: one (1) minute

DRUG

0.76% sodium monofluorophosphate

Brush twice daily (morning and evening) Duration of exposure: one (1) minute

DRUG

0.454% stannous fluoride toothpaste

brush twice daily (morning and evening) Duration of exposure: one (1) minute

Sponsors & Collaborators

  • Colgate Palmolive

    lead INDUSTRY

Principal Investigators

  • Farid Ayad · FAR ORAL SYSTEMIC HEALTH CONSULTING INC.

  • Maha Hetata · FAR ORAL SYSTEMIC HEALTH CONSULTING INC

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-11-26
Primary Completion
2018-12-08
Completion
2018-12-08
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07738198 on ClinicalTrials.gov