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Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel Dentifrice

NCT07215767 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 850

Last updated 2026-02-05

No results posted yet for this study

Summary

The aim of this clinical study is to demonstrate the superior antihypersensitivity efficacy of a novel stannous fluoride (SnF2) and potassium nitrate (KNO3) dentifrice (Investigational Product), compared to SnF2 only, KNO3 only and Vehicle dentifrices, after 8 weeks twice daily use.

Conditions

  • Dentin Hypersensitivity

Interventions

DRUG

Stannous fluoride and Potassium nitrate Dentifrice

Fluoride dentifrice

DRUG

Stannous fluoride Dentifrice

Fluoride dentifrice

DRUG

Potassium nitrate Dentifrice

Non-fluoride dentifrice

DRUG

Vehicle Dentifrice

Placebo dentifrice

Sponsors & Collaborators

  • HALEON

    lead INDUSTRY

Principal Investigators

  • Pejmon Amini · Silverstone Research

  • Jeffery L Milleman · Salus Research, Inc

  • John T Gallob · All Sum Research

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
12 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-09-16
Primary Completion
2026-08-31
Completion
2026-08-31
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07215767 on ClinicalTrials.gov