Discontinuation One Week Recommendations for GLP-1 Receptor Agonists Prior to Esophagogastroduodenoscopy.
NCT07736911 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 140
Last updated 2026-07-30
Summary
This study aims to evaluate the impact of a one-week discontinuation of long-acting glucagon-like peptide-1 receptor agonists (GLP-1 RAs) prior to Esophagogastroduodenoscopy on gastric preparation quality and the need for repeat esophagogastroduodenoscopy (EGD), in order to determine whether a one-week drug interruption constitutes an appropriate pre-procedural recommendation.
Conditions
- GLP-1
Interventions
- DRUG
-
Stop for 1 week
Stop for 1 week
- DRUG
-
GLP-1 non stop
GLP-1 non stop
Sponsors & Collaborators
-
Fu Jen Catholic University Hospital
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-06-01
- Primary Completion
- 2029-06-01
- Completion
- 2030-06-30
Countries
- Taiwan
More Related Trials
-
GLP_1 RA Ultrasound Study
NCT06581120 ·Status: ENROLLING_BY_INVITATION
-
GLP-1 Inhibits Prandial Antro-duodeno-jejunal Motility in Humans
NCT02731664 ·Status: COMPLETED ·Phase: PHASE1
-
The Impact of GLP Medication on Colonoscopy Bowel Preparation Quality
NCT07127354 ·Status: RECRUITING ·Phase: PHASE4
-
Residual Gastric Content After Holding of Glucagon-like Peptide-1 Receptor Agonists Before Elective Surgery
NCT06500143 ·Status: COMPLETED
-
Gastric Emptying Recovery After GLP-1 RA Cessation
NCT07360262 ·Status: COMPLETED
-
Effect of Prolonged Fasting Time on Gastric Residual Volume in Patients Taking GLP1 Receptor Agonists
NCT07006142 ·Status: RECRUITING ·Phase: NA
-
Investigation of the Evolution of Gastric Emptying by Gastric Ultra Sonography in Patients Treated With GLP-1 Receptor Agonists on a 7 Days Pausing Period.
NCT06388213 ·Status: NOT_YET_RECRUITING
-
Investigation of Gastric Emptying by Gastric Ultrasonography in Diabetic Patients Treated With GLP-1 Receptors
NCT07506356 ·Status: RECRUITING
-
Gastric Ultrasound Assessment for Patients Taking GLP1 Agonists
NCT06003985 ·Status: COMPLETED
-
Effects of Beginning a GLP1-Agonist Therapy on Residual Gastric Content and Gastric Emptying
NCT06659159 ·Status: NOT_YET_RECRUITING
-
GLP-1 Receptor Agonist Use and Incidence of Retained Gastric Food on Endoscopy
NCT05875636 ·Status: COMPLETED
-
Protective Benefits of a Clear Liquid Diet on Residual Gastric Content in Patients Taking Glucagon Like Peptide-1 Receptor (GLP-1 RA) Agonist Prior to Anesthesia
NCT06654219 ·Status: RECRUITING ·Phase: NA
-
Impact of a One-Week Discontinuation of Semaglutide on Gastric Retention and Endoscopic Mucosal Visibility Scores
NCT07152756 ·Status: NOT_YET_RECRUITING
-
Antrum Size, Glucagon-like Peptide 1 Levels and Glycemic Control After Sleeve Gastrectomy in Morbid Obese Diabetic Adolescents
NCT04388059 ·Status: COMPLETED
-
The Construction and Validation of a Risk Prediction Model for Perioperative Hypoglycemia in Digestive Endoscopy
NCT07132476 ·Status: COMPLETED
-
Semaglutide and Preoperative Residual Gastric Volumes
NCT06263595 ·Status: COMPLETED
-
Gastric Ultrasound Assessment for Preoperative Prandial State of Patients Taking Glucagon-Like Peptide-1 Receptor Agonists
NCT05889637 ·Status: COMPLETED
-
Influence of Gut Hormones on Food Intake After Roux-en-Y Gastric Bypass Surgery
NCT02336659 ·Status: COMPLETED ·Phase: NA
-
Effect of Teduglutide on Gastric Emptying in Healthy Subjects
NCT01209351 ·Status: COMPLETED ·Phase: PHASE1
-
Intestinal Glucagon-like Peptide-1 (GLP-1) and the Physiological Role in Eating in Humans
NCT01900340 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of a Test Meal on Satiation Hormones in Obese and Normal Weight Adolescents
NCT02020395 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluate the Detection of Retained Gastric Contents and Assess Safety Using the Flower Capsule Endoscopy in Healthy Individuals and GLP-1 Receptor Agonist Users
NCT06927401 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Evaluation of Apraglutide on Gastric Emptying
NCT05995704 ·Status: COMPLETED ·Phase: PHASE1
-
Oral Administration of Peptides; Absorption From Gastrointestinal Tract
NCT00468884 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy of Domperidone (a Prokinetic Agent) on Time in Range in Digestively Asymptomatic Type I Diabetic Patients With Delayed Gastric Emptying (Gastro-TIR)
NCT06695962 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3