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Tissue Adhesive vs Silk Sutures After Mandibular Third Molar Extraction

NCT07735598 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 47

Last updated 2026-07-30

No results posted yet for this study

Summary

Summary: This study compares two methods used to close the gum after the surgical removal of impacted lower wisdom teeth: a medical tissue adhesive and traditional silk sutures. Both closure techniques are evaluated for postoperative pain, bleeding, healing, and the local inflammatory response.

Conditions

  • Mandibular Third Molar/Surgery

Interventions

PROCEDURE

mandibular third molar extraction - surgical glue

The experimental intervention consists of primary flap closure using n-hexyl-cyanoacrylate tissue adhesive (Ifabond® Glue) following surgical extraction of impacted mandibular third molars. The adhesive is applied directly along the wound margins under dry conditions, without the use of sutures, allowing polymerization to achieve wound approximation.

PROCEDURE

mandibular third molar extraction - silk suture

The control intervention consists of primary flap closure using three interrupted 3/0 silk sutures following surgical extraction of impacted mandibular third molars. After repositioning the mucoperiosteal flap, interrupted sutures are placed to achieve primary wound closure according to standard surgical practice.

Sponsors & Collaborators

  • University of Turin, Italy

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-10
Primary Completion
2026-06-10
Completion
2026-07-10

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07735598 on ClinicalTrials.gov