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Individualized Supramaximal Stimulation Current During Continuous Neuromonitoring in Thyroid Surgery

NCT07710365 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 623

Last updated 2026-07-17

No results posted yet for this study

Summary

Continuous intraoperative neuromonitoring (C-IONM) is increasingly used during thyroid surgery to detect early changes in recurrent laryngeal nerve function and reduce the risk of nerve injury. Current clinical practice recommends the use of fixed supramaximal stimulation currents; however, these recommendations are based on limited experimental evidence and may not account for individual variability between patients.

This retrospective observational cohort study aims to determine patient-specific supramaximal stimulation currents (SSC) during C-IONM and to evaluate whether individualized stimulation provides monitoring quality comparable to conventional fixed-current stimulation while potentially reducing unnecessary stimulation intensity. The study also investigates factors influencing electromyographic response amplitudes during surgery and assesses the safety of individualized stimulation parameters.

Conditions

  • Thyroid Disease

Interventions

PROCEDURE

Continuous intraoperative neuromonitoring with fixed stimulation current

Continuous vagus nerve stimulation during thyroid surgery using a fixed supramaximal stimulation current of 1.5 mA.

PROCEDURE

Continuous intraoperative neuromonitoring with individualized stimulation current

Continuous vagus nerve stimulation during thyroid surgery using an individually determined supramaximal stimulation current established at the beginning of the procedure.

Sponsors & Collaborators

  • Medical University of Gdansk

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-06-18
Primary Completion
2024-07-25
Completion
2025-02-11

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07710365 on ClinicalTrials.gov