MedTrace Logo

BIOANCIENT: Cohort of Centenarians in Navarra (1926-1927)

NCT07707297 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 333

Last updated 2026-07-16

No results posted yet for this study

Summary

Demographic aging is a growing global challenge, driven by increasing life expectancy and declining birth rates, with projections indicating that more than 30% of the European population will be over 65 years old by 2100. Centenarians represent a unique biological model of extreme longevity, often exhibiting delayed onset of age-related diseases and preserved functional capacity.

This study aims to establish an intergenerational cohort of centenarians in Navarra (Spain) to investigate the biological, clinical, environmental, and lifestyle factors associated with extreme longevity. By integrating multidimensional data-including clinical assessments, functional and cognitive measures, and biological markers-this study seeks to improve understanding of aging mechanisms and identify potential determinants of healthy aging.

Conditions

  • Aging
  • Cellular Senescence
  • Biomarkers / Blood
  • Age-Related Diseases
  • Frailty

Sponsors & Collaborators

  • Government of Navarra

    collaborator OTHER_GOV

  • Fundacion Miguel Servet

    lead OTHER

Principal Investigators

  • Nicolas Martínez Velilla, MD and PhD · Navarrabiomed, Hospital Universitario de Navarra, IdisNa, Universidad Pública de Navarra

  • Chenhui Chen, MD · Navarrabiomed, Hospital Universitario de Navarra, IdisNa, Universidad Pública de Navarra

  • Enrique Santamaría, PhD · Navarrabiomed, Hospital Universitario de Navarra, IdisNa, Universidad Pública de Navarra

Eligibility

Min Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-02-04
Primary Completion
2027-12-31
Completion
2027-12-31

Countries

  • Spain

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07707297 on ClinicalTrials.gov