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Molecular Profiling of Stage II and III Breast Cancer in Latin American Women Receiving Standard-of-Care Treatment

NCT02326857 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1334

Last updated 2020-09-25

No results posted yet for this study

Summary

Background:

\- Researchers want to learn more about breast cancer in Latin American women. They also want to learn how and why women respond differently to standard treatment. Tissue and blood samples from women with breast cancer are needed to study this disease in order to find new ways to prevent, diagnose, and treat it.

Objective:

\- To learn more about the biology and genetics of breast cancer in Latin American women.

Eligibility:

\- Latin American women age 18 and older of all ethnic backgrounds who have clinical stage II or III breast cancer. They must still be active and able to self-care.

Design:

* Participants are only agreeing to have extra tissue or blood samples collected. They are also letting tissue left over from surgery be used for research. No procedures outside of standard care will be done.
* Participants may have a medical history, physical exam, and blood tests. They may have a pregnancy test. They may have an ultrasound, mammogram, and other scans. They may have an intravenous needle placed in an arm vein.
* Participants may have a core biopsy. For this, a needle is inserted into the breast. A piece of tissue is extracted.
* Participants who have chemotherapy may have blood taken after treatment/before surgery. Tissue may also be collected.
* Participants will complete a questionnaire. It will ask about their social and economic background. It will ask about their family history of cancer. It will also ask about access to diagnosis and treatment of breast cancer.
* Participants may be followed for up to 5 years.

Conditions

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    lead NIH

Principal Investigators

  • Thomas G Gross, M.D. · National Cancer Institute (NCI)

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-12-23
Primary Completion
2014-12-23
Completion
2020-09-23

Countries

  • Argentina
  • Brazil
  • Chile
  • Mexico
  • Uruguay

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02326857 on ClinicalTrials.gov