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A Study to Investigate the Efficacy of an Experimental Dentifrice Containing Stannous Fluoride in Improving Gingival Health

NCT07704905 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 110

Last updated 2026-08-12

No results posted yet for this study

Summary

The aim of this study will be to evaluate the ability of using an experimental dentifrice containing 0.454 percent (%) weight for weight (w/w) Stannous Fluoride (SnF2) to reduce gingivitis and plaque accumulation, compared with a regular fluoride toothpaste (negative control) in participants with mild to moderate gingivitis.

Conditions

  • Dental Plaque
  • Gingivitis

Interventions

DRUG

Test Dentifrice

Experimental dentifrice containing 0.454% w/w SnF2.

DRUG

Reference Dentifrice (Colgate Cavity Protection Dentifrice)

A marketed regular fluoride dentifrice.

Sponsors & Collaborators

  • HALEON

    lead INDUSTRY

Principal Investigators

  • Jeffery L Milleman, DDS · Salus Research Inc

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-07-13
Primary Completion
2026-10-31
Completion
2026-10-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07704905 on ClinicalTrials.gov