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Stannous Fluoride Toothpaste for Reduction and Treatment of Gingivitis

NCT07640399 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 133

Last updated 2026-06-10

No results posted yet for this study

Summary

This study evaluated the efficacy of a stannous fluoride toothpaste compared to a sodium fluoride control toothpaste in reducing gingivitis, bleeding, and plaque over a 12-week period.

A total of 132 subjects were randomized to one of two treatment groups and assessed at baseline and at Weeks 2, 4, 8, and 12 using standardized clinical indices, including the Modified Gingival Index (MGI), Bleeding Index (BI), and Plaque Index (PI).

Conditions

Interventions

DRUG

Sodium Fluoride Dentifrice

Comparator toothpaste

DRUG

Stannous Fluoride Toothpaste (SnF)

Test toothpaste (0.454% SnF)

Sponsors & Collaborators

  • Church & Dwight Company, Inc.

    lead INDUSTRY

Principal Investigators

  • Annahita Ghassemi · Church & Dwight, Inc.

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-03-17
Primary Completion
2025-06-13
Completion
2025-06-13

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07640399 on ClinicalTrials.gov