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Assessment of Peridontal Inflamatuar Markers in MIH

NCT07701642 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 76

Last updated 2026-07-14

No results posted yet for this study

Summary

The goal of this observational study is to investigate periodontal inflammatory mediators in systemically healthy children aged 8-13 years with and without molar-incisor hypomineralization (MIH) who require initial periodontal treatment due to gingivitis.

The main questions it aims to answer are:

Are the levels of periodontal inflammatory mediators in gingival crevicular fluid different between children with MIH and those without MIH? Is the presence and severity of MIH associated with clinical periodontal parameters and dentin hypersensitivity?

Researchers will compare children with MIH to children without MIH to determine whether MIH is associated with changes in periodontal inflammatory mediator levels and periodontal clinical findings.

Conditions

  • Molar-Incisor Hypomineralization (MIH)

Interventions

PROCEDURE

Initial periodontal treatment

DOS samples will be taken before and after treatment

Sponsors & Collaborators

  • Marmara University

    lead OTHER

Eligibility

Min Age
8 Years
Max Age
13 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-07-16
Primary Completion
2027-08-25
Completion
2027-11-01

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07701642 on ClinicalTrials.gov