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Clinical Outcomes and Host Immune Response in Vascular Graft and Endograft Infections

NCT07696884 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2026-07-10

No results posted yet for this study

Summary

ACHIEVE is a prospective observational cohort and biobank study of patients with suspected or diagnosed central vascular graft or endograft infection. The study also includes patients undergoing elective central vascular graft or endograft implantation and healthy blood donor controls. Participants undergo longitudinal clinical data collection and biospecimen sampling. The study aims to characterize clinical outcomes, host immune responses, inflammatory biomarkers, pathogen-related factors, and novel microbiological diagnostic methods, including microbial cell-free DNA sequencing, in vascular graft and endograft infections.

Conditions

  • Vascular Graft Infection
  • Vascular Endograft Infection
  • Aortic Graft Infection

Sponsors & Collaborators

  • Aalborg University

    collaborator OTHER

  • Central Denmark Region

    collaborator OTHER

  • Randers Regional Hospital

    collaborator OTHER

  • Gødstrup Hospital

    collaborator OTHER

  • Regionshospitalet Horsens

    collaborator OTHER

  • University of Aarhus

    collaborator OTHER

  • Viborg Regional Hospital

    collaborator OTHER

  • Aarhus University Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-05-17
Primary Completion
2033-09-01
Completion
2033-09-01

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07696884 on ClinicalTrials.gov