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Constitution of a Biobank for Studies Related to Organ Transplantation (Lyon Centaure Biocollection)

NCT04687865 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 4000

Last updated 2025-03-07

No results posted yet for this study

Summary

This study aims to constitute a collection of biological materials from in transplant patients and to provide biological materials from transplanted patients in order :

i) validate new theory on the cause of allograft loss, ii) develop innovative biomarker for rejection and other transplantation-related conditions (such as BK virus nephropathy, Post-transplant lymphoproliferative disorder ( PTLD) ...)

Conditions

  • Organ Transplantation

Interventions

OTHER

Biobank

For each patient included in the study the following samples will be collected at the indicated time points after transplantation: * Serum samples and plasma sample: Day1, Month 1, Month 3, Month 6, Month 12, month 60, month 120 and at the time of each allograft biopsy. * Urines samples: Month 3 and Month 12 and at the time of each allograft biopsy. * Peripheral Blood Mononuclear Cell (PBMC): for each organ allograft biopsy. * Allograft biopsies: systematically at Month 3, and Month 12, and for cause in case of allograft dysfunction.

Sponsors & Collaborators

  • Hospices Civils de Lyon

    lead OTHER

Principal Investigators

  • Olivier Thaunat, MD · Edouard Herriot Hospital - Transplantation department

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-01-08
Primary Completion
2040-01-08
Completion
2040-01-08

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04687865 on ClinicalTrials.gov