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Electronic Health Record Augmented LDL-Cholesterol Optimization and Control Via Active Lipid Engagement (EHR-LOCALE): A Quality Improvement Implementation Study

NCT07685639 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 2000

Last updated 2026-07-06

No results posted yet for this study

Summary

The purpose of this study is to determine whether a proactive, EHR-guided approach helps more individuals reach safe cholesterol levels, improves medication use, and reduces future heart attacks and strokes, compared to usual care.

The main question it aims to answer is:

• Does the EHR-LOCALE pathway increases the proportion of patients who reach the LDL-cholesterol target of \<1.8 mmol/L at 6 months?

Participants in the interventional group receive:

* Pharmacist contact
* Repeat lipid requisitions
* Review of medications, adherence, and side effects
* Treatment escalation according to national dyslipidemia guidelines

Conditions

Interventions

OTHER

Pharmacist-led lipid optimization pathway

Referral to a centralized, pharmacist-led, telephone clinic for optimization of dyslipidemia management

Sponsors & Collaborators

Principal Investigators

  • Pishoy Gouda, MD · University of Alberta

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-08-31
Primary Completion
2027-09-30
Completion
2027-09-30

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Entities

Diseases
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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07685639 on ClinicalTrials.gov