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Local Corticosteroid Injection Versus Open Surgical Release in De Quervain Tenosynovitis: A Single-Center Study

NCT07683429 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2026-07-06

No results posted yet for this study

Summary

This quasi-experimental study compared pain outcomes following local corticosteroid injection (CSI) versus open surgical release in 100 patients with clinically confirmed De Quervain tenosynovitis unresponsive to conservative management. Patients were allocated to treatment based on clinician judgment and patient preference. Pain was assessed using the Visual Analog Scale (VAS) at baseline, one month, and six months post-intervention. The study was conducted at a single tertiary care centre in Rawalpindi, Pakistan between March 2023 and April 2025.

Conditions

  • DeQuervain's Tenosynovitis

Interventions

DRUG

Triamcinolone acetonide with lidocaine

Triamcinolone acetonide 40mg/mL (1mL) + 1% lidocaine (1mL) - single injection

PROCEDURE

Open surgical release of first dorsal extensor compartment

Longitudinal decompression of the fibro-osseous sheath overlying APL and EPB tendons

Sponsors & Collaborators

  • Rawalpindi Teaching Hospital, District Headquarter Hospital, Rawalpindi

    lead OTHER_GOV

Principal Investigators

  • Saad Riaz, FCPS Orthopedic Surgery · Rawalpindi Teaching Hospital.

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-03-03
Primary Completion
2025-04-03
Completion
2025-04-20

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07683429 on ClinicalTrials.gov