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IL-6 and Cortisol Responses to Cycling Exercise

NCT07681362 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 27

Last updated 2026-07-06

No results posted yet for this study

Summary

This study aimed to investigate salivary interleukin-6 (IL-6) and cortisol responses following short-term and long-term cycling exercise in team athletes with different cardiorespiratory fitness levels. Participants completed a Wingate anaerobic cycling test and a YMCA submaximal cycling test in a randomized crossover design separated by a seven-day washout period. Saliva samples were collected before exercise, immediately after exercise, and 30 minutes after exercise to determine IL-6 and cortisol concentrations. The study also examined whether cardiorespiratory fitness level influenced the magnitude of these physiological responses.

Conditions

  • Exercise Physiology
  • Cardiorespiratory Fitness
  • Interleukin-6
  • Cortisol

Interventions

BEHAVIORAL

Wingate Anaerobic Cycling Test

Participants performed a 30-second all-out Wingate anaerobic cycling test to evaluate acute physiological responses. Saliva samples were collected before exercise, immediately after exercise, and 30 minutes after exercise for cortisol and interleukin-6 analysis.

BEHAVIORAL

YMCA Submaximal Cycling Test

Participants performed a YMCA submaximal cycling test to assess cardiorespiratory fitness and exercise-induced physiological responses. Saliva samples were collected before exercise, immediately after exercise, and 30 minutes after exercise for cortisol and interleukin-6 analysis.

Sponsors & Collaborators

  • Ondokuz Mayıs University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-05-05
Primary Completion
2025-06-05
Completion
2025-06-05

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07681362 on ClinicalTrials.gov