LRRK2 (Leucine-Rich Repeat Kinase 2) Parkinson's Disease Fingerprint
NCT07681219 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2026-07-10
Summary
The goal of this interventional monocentric study is to identify molecular and clinical markers of LRRK2-related Parkinson's disease through blood markers analysis and deep clinical phenotyping. Patients who meet the inclusion criteria, after signing the informed consent form will be clinically evaluated by a neurologist expert in movement disorders. Eventually, patients will undergo a blood sample collection, a brain MRI, and a high density EEG. All data will be collected using an ad hoc electronic Case Report Form (CRF) developed for the study
Conditions
- Parkinsons Disease (PD)
- LRRK2
Interventions
- DIAGNOSTIC_TEST
-
The interventions of the study are the study of blood biomarkers and neuroimaging and neurophysiological data
* Blood sample collection and markers analysis * Brain 1.5 T MRI * High density EEG
Sponsors & Collaborators
-
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- SCREENING
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 30 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-09-01
- Primary Completion
- 2029-09-01
- Completion
- 2029-09-01
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