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Extracellular Vesicles for Rejection Monitoring in Cardiac Transplantation

NCT07673536 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2026-07-01

No results posted yet for this study

Summary

This study will analyze extracellular vesicle (EV)-derived protein profiles in heart transplantated patients during the first 15 months post-transplantation to investigate, if there are distinct EV-derived proteins or protein patterns that allow early and reliable diagnosis of acute cardiac allograft rejection. Additionally, it will explore temporal changes in the EV-derived protein profile during the early postoperative period irrespective of acute allograft rejection, and will investigate, if there are correlations between EV protein markers and imaging findings.

Conditions

  • Rejection Heart Transplant

Sponsors & Collaborators

  • Laurenz Kopp Fernandes

    lead OTHER

Principal Investigators

  • Felix Schoenrath, Prof · Charité Universitaetsmedizin Berlin

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-06-18
Primary Completion
2028-09-30
Completion
2028-11-30

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07673536 on ClinicalTrials.gov