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Multimodal Analysis of Endomyocardial Biopsies

NCT07359690 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 216

Last updated 2026-01-22

No results posted yet for this study

Summary

The goal of this observational study is to pursue a multimodal approach to identify the molecular signatures and immune signalling molecules of various myocardial diseases and thereby contribute to improving diagnosis and therapy.

The main aim is:

-Identification of molecular profiles (e.g., proteome, lipidome, metabolome) and immune signalling profiles that are specifically associated with different myocardial diseases and the post-heart transplantation course.

Participants already receiving an endomyocardial biopsy as part of their regular medical care will be enrolled. An additional biopsy sample will be taken for the above mentioned research.

Conditions

  • Heart Transplantation
  • Dilated Cardiomyopathy (DCM)
  • Hypertrophic Cardiomyopathy (HCM)
  • Myocarditis, Pericarditis
  • Amyloidosis Cardiac
  • Cardiomyopathies
  • Sarcoidosis of the Heart

Sponsors & Collaborators

  • University Hospital, Essen

    lead OTHER

Principal Investigators

  • Lars Michel, PD Dr. med. · Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center Essen, University Hospital Essen, Germany

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-10-27
Primary Completion
2028-09-30
Completion
2028-09-30

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07359690 on ClinicalTrials.gov