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Effect of Certain Denture Disinfectants on Surface Topography, Microhardness and Dimensional Stability of CAD/CAM Milled Polymethyl Methacrylate and Polyether Ether Ketone Denture Base Materials

NCT07672847 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 88

Last updated 2026-06-29

No results posted yet for this study

Summary

This study aims to evaluate and compare the influence of different denture cleansing methods using 1% sodium hypochlorite solution, 0.2% chlorhexidine solution and effervescent alkaline peroxide tablet solution -according to manufacturer's instructions- on surface roughness , microhardness and dimensional stability (%) of CAD-CAM Milled both Polymethyl methacrylate and Polyether Ether Ketone denture base materials.

Conditions

  • Denture
  • CAD/CAM
  • Stability
  • PEEK
  • PMMA

Interventions

OTHER

M0 group

Immersed in distilled water at 37 c for 6 months

OTHER

M1 group : PMMA+ Sodium hypochlorite

Immersed in 1% sodium hypochlorite solution for 6 months

OTHER

M2 group: PMMA+ Chlorhexidine

Immersed in 0.2% chlorhexidine solution for 6 months

OTHER

M3 group : PMMA + Effervescent Alkaline Peroxide Tablet

Immersed in Effervescent tablet denture cleanser solution for 6 months

OTHER

E0 group : PEEK control group

Immersed in distilled water at 37 c for 6 months

OTHER

E1 group : PEEK + Sodium hypochlorite

Immersed in 1% sodium hypochlorite solution for 6 months

OTHER

E2 group : PEEK +Chlorhexidine group

Immersed in 0.2% chlorhexidine solution for 6 months

OTHER

E3 group: PEEK + Effervescent Alkaline Peroxide Tablet

Immersed in Effervescent tablet denture cleanser solution for 6 months

Sponsors & Collaborators

  • Menoufia University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-31
Primary Completion
2026-09-30
Completion
2026-10-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07672847 on ClinicalTrials.gov