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The Effects of Chlorhexidine/Thymol Varnish on Partial Denture Patient

NCT02202304 · Status: WITHDRAWN · Phase: PHASE4 · Type: INTERVENTIONAL

Last updated 2017-05-15

No results posted yet for this study

Summary

Cervitec, a chlorhexidine based varnished has been proven to reduce caries risk in younger populations. This study wants to investigate if the use of this product would reduce the risk of losing abutment teeth on patients that are wearing partial dentures as the literature has proven that these teeth are more prone to caries and periodontal disease.

The primary objectives of this research project are to:

1. Assess if the topical application of CHX/thymol varnish every three months on partial denture abutment teeth results in a clinicallu significant decrease in any loss of attachment compared to no application, and
2. Assess if the topical application of CHX/thymol vanirhs every three months on partial denture abutment teeth results in a clinically significant decrease in carious lesion development or progression compared to no application.

The secondary objectives of this research project are to:

1\. Assess of the topical application of CHX/thymol varnish every three months on partial denture abutment teeth compared to no application results in a clinically significant difference in:

1. Bleeding on probing (BoP).
2. Plaque formation.
3. Periodontal pocket depths.
4. Microbial composition and GCF cytokine profile of the sub gingival environment.
5. The patients self perception of oral health.

Conditions

  • Periodontal Disease
  • Caries

Interventions

DRUG

Chlorhexidine/Thymol varnish

This will be applied on abutment teeth on partial denture wearers every 3 months during a period of 2 years.

Sponsors & Collaborators

  • Ivoclar Vivadent AG

    collaborator INDUSTRY

  • Rosa Moreno Lopez

    lead OTHER

Principal Investigators

  • Rosa Moreno Lopez, BDS · University of Aberdeen

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-09-10
Primary Completion
2019-09-10
Completion
2020-12-10

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02202304 on ClinicalTrials.gov