Development and Validation of a Machine Learning Model for Differentiating Diabetic Kidney Disease and Non-Diabetic Kidney Disease in Type 2 Diabetes
NCT07672639 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 2201
Last updated 2026-06-29
Summary
This multicenter retrospective observational study aims to develop and validate an interpretable machine learning model for differentiating diabetic kidney disease (DKD) from non-diabetic kidney disease (NDKD) in patients with type 2 diabetes mellitus. Clinical, laboratory, and pathological data from biopsy-confirmed patients were collected from 14 medical centers in China. Multiple machine learning algorithms were evaluated and externally validated. The final model was implemented as a web-based clinical decision support tool.
Conditions
- Diabetic Kidney Disease
- Type 2 Diabetes
- Chronic Kidney Disease
Sponsors & Collaborators
-
Beijing Tongren Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-01-01
- Primary Completion
- 2022-12-01
- Completion
- 2024-12-01
Countries
- China
Study Locations
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