Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver)
NCT07665372 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80
Last updated 2026-06-26
Summary
This research is being done to better understand opportunistic infections and cancer in transplant recipients with HIV who receive livers from a donor with HIV compared to livers from donors without HIV.
Conditions
Interventions
- OTHER
-
HIV D+/R+
Receipt of liver transplant from a deceased donor with HIV
- OTHER
-
HIV D-/R+
Receipt of liver transplant from a deceased donor without HIV
Sponsors & Collaborators
-
National Institute of Allergy and Infectious Diseases (NIAID)
collaborator NIH - lead OTHER
Principal Investigators
-
Christine Durand, MD · Johns Hopkins University
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-09-30
- Primary Completion
- 2030-08-31
- Completion
- 2031-08-31
Countries
- United States
Study Locations
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