Interplay of Central and Peripheral Vascular Effects of Insulin in Obesity

NCT07653464 · Status: NOT_YET_RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2026-07-28

No results posted yet for this study

Summary

Determine the impact of obesity with insulin resistance on the neurovascular response to brain insulin stimulation.

Conditions

Interventions

DRUG

human insulin

Participants will be administered human insulin (160 IU) using an intra-nasal device.

Sponsors & Collaborators

  • University of Missouri-Columbia

    lead OTHER

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-10-31
Primary Completion
2031-06-30
Completion
2032-06-30
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07653464 on ClinicalTrials.gov