Interplay of Central and Peripheral Vascular Effects of Insulin in Obesity
NCT07653464 · Status: NOT_YET_RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 64
Last updated 2026-07-28
Summary
Determine the impact of obesity with insulin resistance on the neurovascular response to brain insulin stimulation.
Conditions
- Obesity (BMI>30)
- Insulin Resistance
Interventions
- DRUG
-
human insulin
Participants will be administered human insulin (160 IU) using an intra-nasal device.
Sponsors & Collaborators
-
University of Missouri-Columbia
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-10-31
- Primary Completion
- 2031-06-30
- Completion
- 2032-06-30
- FDA Drug
- Yes
Countries
- United States
Study Locations
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