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Comparison Immune Response in Paravertebral and Erector Spinal Plane Block in Breast Cancer Patients

NCT07648810 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 56

Last updated 2026-06-15

No results posted yet for this study

Summary

The goal of this clinical trial is to find the difference in immune response between two types of regional anesthesia in female patients suffering from breast cancer.

The main question it aims to answer is there a difference in the immune response between paravertebral block and erector spinal plane block.

Hypothresis of the study is that paravertebral block with propofol induces less immune response in surgical treatment of breast cancer patients than erector spinal plane block.

Participants will be asked to sign the informant consent. They will be given either paravertebral block or erector spinae plane block with general anesthesia using propofol. Their venous blood will be taken 1 hour prior surgery and 24 and 48 hours after surgery.

Conditions

  • Breast Cancer - Female

Interventions

PROCEDURE

Regional Anesthetic Injection

Draw of venous blood and application of paravertebral and erector spinae plane block

PROCEDURE

Blood draw for the laboratory assessment

Draw of venous blood 24 hours after surgery

PROCEDURE

Blood draw for the laboratory assessment

Blood draw 48 hours after surgery

Sponsors & Collaborators

  • Clinical Hospital Center Rijeka

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-06-15
Primary Completion
2026-10-15
Completion
2027-04-15

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07648810 on ClinicalTrials.gov