Comparison of The Effects Of General Anesthesia and PECS Block Methods on Blood Counts in Patients With Breast Cancer
NCT06151639 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 50
Last updated 2025-09-04
Summary
Regional anesthesia and local anesthetics have proven anti-inflammatory and antitumor effects as well as their analgesic properties.
On this trial, the investigators are searching anesthetic techniques affect on the leukocyte, platelet-lymphocyte count and ratios, total amount of opioids used, and discharge times in patients who will undergo wire localized lumpectomy operation.
Conditions
Interventions
- PROCEDURE
-
general anesthesia
General anesthesia was performed by muscle relaxant(rocuronium 0,6 mg/kg), opioids(phentanyl 1-2 mcg/kg) and propofol 2mg/kg. Inhation anesthetics and remiphentanyl infusion were used for maintance general anesthesia.
- PROCEDURE
-
peripheral nerve blocks
With the help of ultrasonography, at the 2nd rib level, between the fasciae of the pectoralis major and minor muscles at the mid-clavicle level (PECS I block, interpectoral fascial plane block) and at the 4th rib level, at the mid-axillary level, between the fasciae of the pectoralis minor and serratus muscles (PECS II block, pectoroseratal fascial plane block) local anesthesia was applied. In patients who underwent PECS block, a high-frequency linear ultrasonography (Esaote, My LabFive-Genova, Italy) probe and a 50 mm tip insulated needle (echoplex+, Vygon Ecouen-France) were used. 0.200% bupivacaine 15 ml was applied for the PECS I block, and 0.200% bupivacaine 20 ml was applied for the PECS II block, and fascial separation was observed. Sensory control was performed in the breast and axilla area and the patients were taken into surgery.
Sponsors & Collaborators
-
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
lead OTHER
Principal Investigators
-
Guldeniz ARGUN · Dr. Abdurrahman Yurtaslan Oncology Train and Research Hospita
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-08-01
- Primary Completion
- 2025-01-10
- Completion
- 2025-03-03
Countries
- Turkey (Türkiye)
Study Locations
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