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Efficacy of Lasers, Propolis-Based Agent, and Sham for Dentine Hypersensitivity

NCT07647861 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 140

Last updated 2026-06-15

No results posted yet for this study

Summary

Dentine hypersensitivity is a common clinical problem. Although Nd:YAG lasers, diode lasers, and topical desensitizing agents are widely utilized, long-term comparative evidence regarding their clinical efficacy remains limited. This prospective, randomized, parallel-arm, evaluator-blind, sham-controlled clinical trial evaluated and compared the 12-month clinical performance of an Nd:YAG laser, a diode laser, a herbal propolis-based dentin barrier agent, and a sham application.

Conditions

  • Dentine Hypersensitivity

Interventions

DEVICE

Nd:YAG Laser Application

Nd:YAG laser application performed for the treatment of dentine hypersensitivity.

DEVICE

Diode Laser Application

Diode laser application performed for the treatment of dentine hypersensitivity.

OTHER

Herbal Propolis-Based Dentin Barrier Agent

Topical application of a herbal propolis-based dentin barrier agent.

OTHER

Sham Application

Placebo/sham procedure to simulate treatment without delivering active laser or therapeutic agent benefits

Sponsors & Collaborators

  • Ondokuz Mayıs University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-12-15
Primary Completion
2026-06-10
Completion
2026-06-10

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07647861 on ClinicalTrials.gov